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PREVALENSI KASUS OTITIS EKSTERNA BERDASARKAN USIA, JENIS KELAMIN DAN DIABETES MELITUS DI POLIKLINIK THT RSUP SANGLAH DENPASAR TAHUN 2018 Putu Wahyu Dyatmika Tanaya; Agus Rudi Asthuta; Komang Andi Dwi Saputra; I Wayan Sucipta
E-Jurnal Medika Udayana Vol 9 No 3 (2020): Vol 9 No 03(2020): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2020.V09.i3.P16

Abstract

ABSTRAK Otitis eksterna merupakan permasalahan dan kelainan pada telinga, hidung dan tenggorok (THT), merupakan kasus yang tergolong umum dan sering ditemui oleh dokter dalam praktek di lapangan baik dalam usia anak-anak maupun dewasa, dimana dari tahun ke tahun kasus tersebut terus mengalami peningkatan. Studi deskriptif ini dilakukan untuk mengetahui prevalensi kasus otitis eksterna berdasarkan usia, jenis kelamin dan diabetes melitus di Poliklinik THT RSUP Sanglah Denpasar tahun 2018. Desain penelitian cross-sectional dengan metode pengambilan melalui teknik total sampling di Poliklinik THT RSUP Sanglah Denpasar pada tahun 2018. Total 70 sampel yang ada, hasil menunjukan kelompok usia tertinggi pasien otitis eksterna adalah pada masa Remaja Akhir (17-25 tahun) sebesar 24,3%. Pasien otitis eksterna berjenis kelamin laki-laki (60%) lebih banyak terdiagnosis otitis eksterna dan sebagian besar pasien tidak memiliki riwayat penyakit diabetes melitus (97,1%). Diagnosis otitis eksterna yang sering ditemukan adalah otitis eksterna akut terlokalisir (95,7%). Berdasarkan hasil penelitian tersebut, masih perlu dilakukan studi yang lebih lanjut dan mendalam untuk mengetahui hubungan dari otitis eksterna dan faktor-faktor yang mempengaruhinya. Kata Kunci: prevalensi, otitis eksterna, THT, RSUP Sanglah
Postoperative Craniopharyngioma in a 10-Year-Old Girl Presenting with Central Precocious Puberty, Central Diabetes Insipidus, and Growth Hormone Deficiency Putri Prashanti, Nyoman Ananda; Putu Wahyu Dyatmika Tanaya; I Wayan Bikin Suryawan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 3 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i3.936

Abstract

Background: Hypopituitarism is the most common endocrinology complication of postoperative craniopharyngioma. However, we found a 10-year-old girl with a history of postoperative craniopharyngioma presenting with central precocious puberty (CPP), central diabetes insipidus (CDI), and growth hormone deficiency (GHD). Case presentation: A 5-year-old girl experienced breast growth followed by menstruation six months later. The patient's weight was 19 kg (weight-for-age: P25-P50), height was 109 cm (height-for-age: P10-P25), and good nutritional status (Waterlow 90%). The stage of pubertal development was M2P2. There was a history of craniopharyngioma, and it was resected at the age of 2 years. After surgery, the patient developed CDI and has received desmopressin. No new tumour growth was found from evaluation with periodic MRIs every three years. After CPP was established, with increased serum levels of LH, FSH, and estradiol, GnRH agonist therapy was given at 100 mcg/kg BW every month. During five years of follow-up, the patient experienced clinical and laboratory improvement. However, the growth is only 3-4 cm/year (<P3) with short stature (height-for-age: <P3) and overweight. Low levels of IGF1 and GH were found in the stimulation test results, so the diagnosis of GHD was confirmed. The patient will receive growth hormone therapy and is expected to reach her potential genetic height (148.5 - 165.5 cm). Conclusion: Even though the craniopharyngioma tumour has been resected and no recurrence has occurred, it is crucial to evaluate the hormones produced by the pituitary thoroughly.
Postoperative Craniopharyngioma in a 10-Year-Old Girl Presenting with Central Precocious Puberty, Central Diabetes Insipidus, and Growth Hormone Deficiency Putri Prashanti, Nyoman Ananda; Putu Wahyu Dyatmika Tanaya; I Wayan Bikin Suryawan
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 3 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i3.936

Abstract

Background: Hypopituitarism is the most common endocrinology complication of postoperative craniopharyngioma. However, we found a 10-year-old girl with a history of postoperative craniopharyngioma presenting with central precocious puberty (CPP), central diabetes insipidus (CDI), and growth hormone deficiency (GHD). Case presentation: A 5-year-old girl experienced breast growth followed by menstruation six months later. The patient's weight was 19 kg (weight-for-age: P25-P50), height was 109 cm (height-for-age: P10-P25), and good nutritional status (Waterlow 90%). The stage of pubertal development was M2P2. There was a history of craniopharyngioma, and it was resected at the age of 2 years. After surgery, the patient developed CDI and has received desmopressin. No new tumour growth was found from evaluation with periodic MRIs every three years. After CPP was established, with increased serum levels of LH, FSH, and estradiol, GnRH agonist therapy was given at 100 mcg/kg BW every month. During five years of follow-up, the patient experienced clinical and laboratory improvement. However, the growth is only 3-4 cm/year (<P3) with short stature (height-for-age: <P3) and overweight. Low levels of IGF1 and GH were found in the stimulation test results, so the diagnosis of GHD was confirmed. The patient will receive growth hormone therapy and is expected to reach her potential genetic height (148.5 - 165.5 cm). Conclusion: Even though the craniopharyngioma tumour has been resected and no recurrence has occurred, it is crucial to evaluate the hormones produced by the pituitary thoroughly.