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All Journal Medicina E-Jurnal Medika Udayana Sari Pediatri Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Bali Journal of Anesthesiology ISM (Intisari Sains Medis) : Jurnal Kedokteran
Ida Bagus Gede Suparyatha
Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Udayana
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Other

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Journal : Paediatrica Indonesiana

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Multiple organ dysfunction syndrome associated with hyperglycemia in children requiring intensive care Hendy Halim; Ida Bagus Gede Suparyatha; I Made Arimbawa; I Nyoman Budi Hartawan
Paediatrica Indonesiana Vol 55 No 4 (2015): July 2015
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (263.507 KB) | DOI: 10.14238/pi55.4.2015.230-4

Abstract

Background Hyperglycemia can be caused by three or more organ dysfunctions and occurs in children requiring intensive care in the first 48 hours. Blood sugar level higher than 140 mg/dl is considered as hyperglycemia in children requiring intensive care.Objective To determine the association between multiple organ dysfunction syndrome (MODS) in children requiring intensive care and hyperglycemia with blood sugar level higher than 140 mg/dl.Methods This case control study without matching was conducted on children aged 1 month-12 years from pediatric ward at Sanglah hospital during June-August 2012. We used consecutive sampling to recruit subjects, which then were screened by Pediatric Risk of Hospital Admission (PRISA) 2 score. All subjects were enrolled for blood sugar test, then divided into 2 groups; hyperglycemia with blood sugar level > 140 mg/dl as case and normoglycemia as control. We used organ dysfunction criteria to determine multiple organ dysfunction. The association between MODS and hyperglycemia was assessed by Chi-square test with 95% confidence interval and a statistical significance value of P < 0.05.Results Fifty two subjects were enrolled in this study. We excluded two subjects, hence each group consisted of 25 subjects. We found 18 subjects under and 7 subjects above five years old in hyperglycemia group. The association between multiple organ dysfunction and hyperglycemia was significant with an odds ratio of 10 (95% CI 3 to 38), P < 0.0001.Conclusion Multiple organ dysfunction syndrome had a significant association with hyperglycemia. Multiple organ dysfunction syndrome with hyperglycemia occurs ten times greater than with normoglycemia.
Pediatric index of mortality 2 scores in pediatric intensive care unit patients Monica Sampurna; Ida Bagus Suparyatha; I Gede Raka Widiana
Paediatrica Indonesiana Vol 56 No 1 (2016): January 2016
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.598 KB) | DOI: 10.14238/pi56.1.2016.43-7

Abstract

Background Comprehensive care for critically ill children in the pediatric intensive care unit (PICU) is done with the aim of achieving good outcomes. Severe disease in children is characterized by disruption of homeostatic processes, and can be evaluated by mortality scoring methods. There are several mortality scoring methods which can be used to predict mortality in children, the pediatric risk of mortality (PRISM) and pediatric index of mortality (PIM) are the most preferably used among all. The pediatric index of mortality 2(PIM2) is a key mortality prediction model for children receiving treatment in intensive care units, but its use has not been well validated in Indonesia.Objective To evaluate the performance of PIM2 model in PICU patients.Methods This cross-sectional study was conducted on PICU patients at Sanglah Hospital from November 2012 to April 2013. Patients underwent PIM2 scoring during their admission. The predictive ability of PIM2 scoring for patient mortality was analyzed using ROC curve.Results A total of 54 patients were included in this study, of whom 8 (14.8%) died. Discrimination between survival and death was assessed by the area under the receiver operating characteristic curve and found to be 0.81 (95% CI 0.59 to 1.03). Sensitivity was 75 (95%CI 36 to 96)% and specificity was 98 (95%CI 87 to 99)%. The PIM2 cut off value was ≥ -0.99.Conclusion The PIM 2 model has a good discriminatory power and calibration for predicting the mortality of children admitted to PICU and therefore is recommended for routine use in clinical practice. [
Co-Authors Alice Indradjaja, Alice Ayu Widyanti Dewi Sutriani Mahalini Dyah Kanya Wati Estina, Vania Catleya Gusti Ayu Putu Sri Satya Mahayani Hendra Salim Hendy Halim I Gde Raka Widiana I Gusti Ayu Putu Eka Pratiwi I Gusti Lanang Sidiartha I Gusti Ngurah Made Suwarba I Gusti Ngurah Sanjaya Putra I Made Arimbawa I Made Bakta I Made Jawi I Made Karma Setiyawan I Nyoman Budi Hartawan I NYOMAN MANTIK ASTAWA I Wayan Gustawan Ida Bagus Subanada Khema Metta Wijaya Luh Putu Diah Virayanti Made Gede Dwi Lingga Utama Made Pande Lilik Lestari Made Wiryana Monica Sampurna Ni Luh Sri Apsari Ni Made Adi Tarini Putu Diah Pratiwi Romy Windiyanto Sekarningrum, Putu A. Siska Permanasari Sinardja Wati, Dyah K. Wayan Sulaksmana Sandhi Parwata