Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Indonesian Journal of Pharmaceutical Science and Technology

The Prediction of Curcumin Content in the Turmeric Rhizome with Raman Handheld Spectroscopy Wirasuta, I Made Agus Gelgel; Dewi, Cokorda Istri Tirta Rusmala; Laksmiani, Ni Putu Linda; Srinadi, I Gusti Ayu Made; Putra, Deddi Prima
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 3 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.832 KB) | DOI: 10.15416/ijpst.v5i3.16315

Abstract

The quality control of herbal medicine should be started from the determination of the active substance at harvest time. The Raman spectrometry has been used for this propose. The aim of this study is to determine the quantification of curcumin in turmeric rhizome (Curcuma longa Linn.) using Raman spectroscopy combined with multivariate analysis of PLS-R that are expected to provide reference method for quality control in turmeric rhizome, especially for raw materials of Herbal drugs. Parameters that can be used for analysis of curcumin levels on turmeric rhizome obtained using intensity of data Raman and the data obtained from the standard method will be processed with multivariate analysis methods PLS-R. The validation value of quantification result using Raman-PLSR is seen from R2 value of 0.957, RMSEC value of 0,199 and p-value of 0.00. The study showed the developed method could be implemented on to determine the prediction quantification of raw material herbal medicine.Keyword : Curcumin,  PLS-R, Turmeric, Raman Spectroscopy
The Prediction of Curcumin Content in the Turmeric Rhizome with Raman Handheld Spectroscopy I Made Agus Gelgel Wirasuta; Cokorda Istri Tirta Rusmala Dewi; Ni Putu Linda Laksmiani; I Gusti Ayu Made Srinadi; Deddi Prima Putra
Indonesian Journal of Pharmaceutical Science and Technology Vol 5, No 3 (2018)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (412.832 KB) | DOI: 10.24198/ijpst.v5i3.16315

Abstract

The quality control of herbal medicine should be started from the determination of the active substance at harvest time. The Raman spectrometry has been used for this propose. The aim of this study is to determine the quantification of curcumin in turmeric rhizome (Curcuma longa Linn.) using Raman spectroscopy combined with multivariate analysis of PLS-R that are expected to provide reference method for quality control in turmeric rhizome, especially for raw materials of Herbal drugs. Parameters that can be used for analysis of curcumin levels on turmeric rhizome obtained using intensity of data Raman and the data obtained from the standard method will be processed with multivariate analysis methods PLS-R. The validation value of quantification result using Raman-PLSR is seen from R2 value of 0.957, RMSEC value of 0,199 and p-value of 0.00. The study showed the developed method could be implemented on to determine the prediction quantification of raw material herbal medicine.Keyword : Curcumin,  PLS-R, Turmeric, Raman Spectroscopy
Co-Authors AA Sudharmawan, AA ADE KUSUMA DEWI Agnes Juliet Boking Agnes Juliet Bokings Agung Dwi Cahya Megamahaputra AGUST WIRAS ARDI KUSUMA ANAK AGUNG ISTRI AGUNG CANDRA ISWARI ANNA FITRIANI AYU SANDRA TIARA DEWI Ayuk Dwi Cahyani Chairun Nisa Cokorda Istri Tirta Rusmala Dewi Deddi Prima Putra DERY MAULANA Desak Putu Eka Nilakusmawati DEWA AYU DWI ASTUTI Dewi, Cokorda Istri Tirta Rusmala DOMINGGAS TEO Dyan Ayu Wijayanti EKA ARISTA ANJASARI Eriska May Wulandari EVARISTUS VERIYOGI YALSCHEN LEMBUNAI G. K. GANDHIADI G. K. GANDHIADI GILANG BIMASAKTI ANDHIKA GUSTI AYU PUTU YULIANDARI GUSTI AYU RATIH ASTARI HIRZI FIRDAUSI I GEDE AGUS JIWADIANA I Gede Purna Adi Putra I GUSTI AYU MADE VALENTINA DEWI I Kadek Yudha Pramana Adi I KOMANG GDE SUKARSA I Komang Gede Sukarsa I Made Agus Gelgel Wirasuta I MADE BUDIANTARA PUTRA I MADE PRABA ESHA SUKSEMAWAN I Nyoman Widana I Putu Eka Nila Kencana I Putu Eka Suarsa I PUTU YUDANTA EKA PUTRA I Wayan Sumarjaya I.K.G. Sukarsa IDA AYU MADE SUPARTINI Isabel Divya Georgiana Walewangko K. Jayanegara KADEK NOVIA DWIJAYANTHI KASTIN DWILEN PONG SUMAE Ketut Jayanegara KHOSYI RUKITO Komang Dharmawan LUH KOMANG MARDIANI Luh Putu Ratna Sundari LUH PUTU SAFITRI PRATIWI LUIS RICARDO PANDIANGAN Luky Adrianto M ARRIE KUNILASARI ELYNA Made Asih MADE AYU DWI OCTAVANNY MADE NARYMURTI WIDYASTUTI Made Novita Dewi Made Susilawati MILATUS SHOLIKHA Mirza Rizaldi Sudrajat MULIA YASMAN NADIYA YUVITA RIZKI NATASYA WIDIA PUTRI Ni Kade Hindu Pertiwi NI KADEK ARISKA DEWI Ni Kadek Dhirayani NI KADEK DWI ARISYA AFRILIANTI NI KADEK ENDAH YANITA UTARI NI LUH GEDE SINTA ARYATI NI LUH NIKASARI Ni Luh Putu Suciptawati NI LUH WIWIN YUNIARTI Ni Made Asih Ni Made Audi Kirei Saraswati Ni Made Putri Ja Yanti NI MADE SEKARMINI NI MADE SRI KUSUMAWARDHANI NI NYOMAN UTAMI DEWI NI PUTU DIAN ASTUTIK Ni Putu Linda Laksmiani Ni Putu Manik Maharani NI PUTU MEILING UTAMI NI PUTU MIRAH SRI WAHYUNI Ni Putu Monikha Alvionitha NI PUTU NIA IRFAGUTAMI NI PUTU PREMA DEWANTI NI PUTU RINA ANGGRENI NI WAYAN ARI SUNDARI NI WAYAN ARIS APRILIA A.P NI WAYAN ASRI PRADNYANI Ni Wayan Dewi Anastasya Pratiwi Ni Wayan Merry Nirmala Yani NI WAYAN YULIANI NI WAYAN YUNI CAHYANI NOVIAN ENDI GUNAWAN NUR FAIZA NURMA ALIYUWANINGSIH NYOMAN GDE PRAJNAWIWEKA RATMASA TARAM NYOMAN KRISHNA PRATIWI DANGIN Nyoman Wendri PALUPI PURNAMA SARI PANDE PUTU BUDI KUSUMA Putu Edi Dimas Saputra PUTU SUSAN PRADAWATI Putu Wulan Cahayaningrat Ratna Sari Widiastuti SORAYA SARAH AFIFAH TJOK GDE SAHITYAHUTTI RANANGGA TRI ALIT TRESNA PUTRA Ulfatun Farika Novitasari ULYATIL AENI Wayan Evi Handayani Wijayakusuma, I Gusti Ngurah Lanang WILDAN FATTURAHMAN MUJTABA Yani Arthayanti ZANUAR SEPTYADI