Marcellus Simadibrata K
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Irritable Bowel Syndrome: Diagnosis and Treatment Muhammad Syafiq; Marcellus Simadibrata K; Murdani Abdullah; E. Mujaddid
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 4, NUMBER 1, April 2003
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/41200314-21

Abstract

Irritable bowel syndrome (IBS) is the most common functional disorder of the gastrointestinal tract. As a result of the lack of specific diagnostic testing and absence of circumscribed biology markers of the disease, its diagnosis is based on a myriad of symptoms. The term irritable bowel syndrome was probably first coined in 1944 by Peters and Bargen. In 1849, Cumming described the clinical manifestations of Irritable Bowel Syndrome. Irritable bowel syndrome is defined on the basis of the recently modified Rome criteria as the presence of at least 12 weeks (not necessarily consecutive) of abdominal discomfort or pain in the preceding 12 months that cannot be explained by structural or biochemical abnormalities, and that has at least two of the following three features: pain relieved with defecation, an onset associated with a change in the frequency of bowel movements (diarrhea or constipation), or an onset associated with a change in form of stool (loose, watery, or pellet-like). The syndrome can be divided into three subcategories according to the Modified Rome criteria II; those with a predominant symptom of diarrhea, constipation, or constipation alternating with diarrhea. There are several criteria for irritable bowel syndrome, one of which is the Manning criteria, applied in many epidemiological and clinical studies to identify irritable bowel syndrome. However, many investigators disagree with this criteria due to a seemingly poor validity in men. In an attempt to bring order to the specialty, consensus-based approach is adopted by a group of international experts, which led to the development of the Rome criteria for irritable bowel syndrome (Table 1). Extra-intestinal symptoms, including headache, backache, urinary and gynecologic symptoms, and fatigue, are more common in the constipation-predominant subgroup.
Management of Esophageal Foreign Body Haryanto Rahardjo; Ari Fahrial Syam; Marcellus Simadibrata K
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 8, ISSUE 1, April 2007
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/81200724-27

Abstract

Foreign body ingestion is a common clinical problem. Objects such as coin, safety pin, meat bolus, bone, denture, etc. are often ingested. They lodge in certain part of esophagus, which may be asymptomatic or develop some symptoms of esophagus or respiratory tract. Plain radiography is indicated for every patient with a known or suspected foreign body. It may appear as radiopaque or radiolucent images. A number of methods can be used to remove esophageal foreign bodies, including: observation, endoscopy, rigid esophagoscopy, Foley catheter extraction, bougienage and sometimes administration of LES relaxant or surgery. Application of those strategies is selected based on the type and location of foreign bodies. Five cases had been managed by different strategies, i.e. two cases were successfully managed by endoscopy; a case was managed through careful observation; another case was managed by pushing object into stomach using endoscopic approach; and the other case was fail when it was managed by Foley catheter but then it was successfully managed by rigid esophagoscopy at ENT Department. All of cases had been managed without any complication. Keywords: esophageal foreign body, foreign body ingestion, procedure removal
The Association of Anxiety and Depression with the Quality of Life of Inflammatory Bowel Disease Patients Simanjuntak, Tiroy Sari Bumi; K, Marcellus Simadibrata; Shatri, Hamzah; Abdullah, Murdani
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 1 (2025): VOLUME 26, NUMBER 1, April, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/261202519-27

Abstract

Background: Inflammatory Bowel Disease (IBD), which is chronic and often recurrent, causes psychological changes in patients. This puts IBD patients at a higher risk of developing various mental disorders, especially anxiety and depression. IBD patients who had symptoms of anxiety or depression tended to show a lower quality of life than patients without those symptoms.Methods: This research uses a cross-sectional design. Data collection was carried out using primary data obtained through interviews with IBD patients who were undergoing outpatient treatment from October to December 2023. Anxiety and depression were measured using the Hospital Anxiety Depression Scale (HADS) and quality of life for IBD patients was measured using the Inflammatory Bowel Disease Questionnaire 9 (IBDQ-9). These questionnaires have been translated into Indonesian and validated. The research sample is an accessible population that has passed the inclusion and exclusion criteria using unpaired numerical analytical sample calculations. The sample used in this research was 172 subjects.Results: In the multivariate analysis, after controlling for confounding variables, the fully adjusted prevalence ratio (PR) for anxiety symptoms was 1.182 (CI: 1.061–1.317, p = 0.002). Similarly, the fully adjusted PR for depression symptoms was 1.221 (CI: 1.075–1.386, p = 0.002).Conclusion: Anxiety and depression are more strongly associated with a decline in the quality of life of IBD patients based on the IBDQ-9 after controlling for confounding variables.Keywords: Anxiety, depression, IBD, quality of life