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Ultrasound-Diagnosed Non-Alcoholic Fatty Liver Disease among Medical Check Up Patients Suharjo B Cahyono; Putut Bayupurnama; Neneng Ratnasari; Sutanto Maduseno; Siti Nurdjanah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 14, NUMBER 3, December 2013
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (135.952 KB) | DOI: 10.24871/1432013145-149

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is recognised as one of the most important causes of chronic liver disease and has become an important health issue in many countries. The aim of the study wasto evaluate the prevalence and risk factors of NAFLD patients based on ultrasound diagnosed in medical check up setting.Method: In this study, of 2,105 patients undergoing medical check up in Charitas Hospital, Palembang between January 2011 to August 2013, 115 NAFLD patients and 113 non-NAFLD patients as controls were included. Diagnosis of NAFLD was based on ultrasound appearance, patients did not consume alcohol, with negative HBsAg and hepatitis C virus antibodies.Results: The prevalence of NAFLD in medical check up patients was 7.9% whereas 39% patients had normal body mass index (BMI) ( 25 kg/m2). Patients with NAFLD compared with non-NAFLD patients had higher values of BMI (p 0.001), triglycerides (p = 0.001), aspartate aminostransferase (AST) (p 0.001), alanine aminotransferase (ALT) (p 0.001), fasting glucose (p = 0.002), and lower HDL cholesterol (p = 0.001). Obesity was the strongest associated factor for NAFLD (95% CI = 1.87-7.85; OR = 3.83; p 0.001), followed by high glucose levels (95% CI = 1.38 - 8.31; OR = 3.83; p = 0.008) and hypertriglyceridemia (95% CI = 1.38 - 4.11;OR = 2.38; p = 0.002).Conclusion: About 7.9% patients suffered from NAFLD. Approximately 39% medical check up patients had NAFLD with normal BMI. Obesity, hypertriglyceridemia and high glucose levels were the risk factors for NAFLD.Keywords: non-alcoholic liver disease, body mass index, prevalence, metabolic syndrome
Colorectal Cancer in Young Patient: A Distinguished Disease Entity? Siti Nurdjanah; Suryo Taroeno; Putut Bayupurnama; Sutanto Maduseno; Neneng Ratnasari
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 6, ISSUE 2, August 2005
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/62200537-41

Abstract

Background: Some studies suggested that colorectal cancer at young age had a distinct biological characteristic: more advanced stage at time of diagnosis, poorer differentiated, and consisted of large proportion of mucin producing tumors. Aim of the study: To analyze clinical and histopathological differences between young aged colorectal cancer patients ( 40 years old) and the older patients Methods: A cross-sectional retrospective study was conducted among our colorectal cancer patients in a general hospital between 1999-2004, using C.18, C.19, C20 ICD X code in medical record searching. It was requested that the patients had surgical treatment in Dr. Sardjito General Hospital. An inconclusive clinical staging and/or histological data were among the exclusion criteria. Chi-square, Fisher’s exact test, T-test, and Mann Whitney U-test was performed to analyze the difference between patients 40 years old and ³ 40 years old, in respect to diagnostic staging, histological type, histological grade (differentiation), CEA level, hemoglobin, albumin, tumor location, and chief complain. With p 0.05 was considered as significant. Results: Sixteen young aged ( 40 years old) and 72 older patients had been identified. No differences in gender proportion and mean of symptoms to diagnosis period between two groups. No statistical differences between young aged and the older patients in diagnostic staging, histological grade and type, CEA level, and hemoglobin. Young aged patients had higher albumin value at presentation (p = 0.014), all had left sided tumors (p = 0.035), more complain of anal pain (p 0.001), and less change of bowel habits complain (p = 0.009) Conclusion: The study results had failed to confirm the difference in respect to diagnostic staging, histological type and grade, CEA level, and hemoglobin. Most of our young aged patients had left sided tumors with chief complain of anal pain, and less complain of change of bowel habits Keywords: Young aged colorectal cancer patients, cross sectional analysis, clinical and histological difference
Endoscopic Sclerotherapy and Band Ligation in Secondary Prophylaxis of Esophageal Variceal Treatment Catharina Triwikatmani; Putut Bayupurnama; Sutanto Maduseno; Neneng Ratnasari; Fahmi Indrarti; Siti Nurdjanah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 11, NUMBER 3, December 2010
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/1132010121-124

Abstract

Background: Variceal bleeding is the most severe outcome of portal hypertension. Endoscopic sclerotherapy and band ligation are endoscopic treatment modalities for both active variceal bleeding and secondary prophylaxis. Endoscopic sclerotherapy has been carried out in Sardjito hospital since 1998, while band ligation has only been carried out since 2007 year. The aim of this study was to evaluate the long-term Result of endoscopic sclerotherapy and endoscopic band ligation in secondary prophylaxis of esophageal variceal eradication. Method: This is not a prospective study and is not randomized. The Results of patients who underwent endoscopic sclerotherapy and endoscopic band ligation from July 2003 to June 2009 were compared. Patients were evaluated for re-bleeding and recurrence rates. Results: Two hundred and seventy seven patients underwent endoscopic sclerotherapy and endoscopic band ligation during the period. One hundred and nine patients with varices eradication data; 49 patients who underwent sclerotherapy and 60 patients who underwent band ligation were followed for 1-119 (15.54 ± 20.70) months. The numbers of sessions for eradication were 4.33 ± 1.16 and 2.23 ± 0.59 for endoscopic sclerotherapy and endoscopic band ligation respectively (p 0.001). Re-bleeding and recurrence rates were 38.64% and 84.21% for endoscopic sclerotherapy, and 25.93% and 70% for endoscopic band ligation (p 0.05). Conclusion: Endoscopic band ligation is more effective than sclerotherapy in the eradication of esophageal varices.   Keywords: esophageal varices, sclerotherapy, band ligation, secondary prophylaxis
The Role of Insulin Resistance in Diabetic Patients with Chronic Liver Disease Neneng Ratnasari; Siti Nurdjanah; Putut Bayupurnama; Sutanto Maduseno
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 9, ISSUE 1, April 2008
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/9120081-3

Abstract

Background: The association between diabetes and chronic liver disease has been well documented. However, the mechanism remains unknown. The aim of this study was to investigate the insulin resistance in chronic liver disease and normal liver in diabetic patient. Method: A total of 31 diabetic, non-alcoholic patients with multiple oral hypoglycemic drugs, either with or without lipid abnormalities were enrolled in this study. Subjects were recruited from outpatient clinic of Department of Endocrine at Dr. Sardjito Hospital, Jogjakarta, Indonesia from May-June 2004. This was a cross sectional study. Fasting insulin and glucose level, liver function test, body mass index, and the presence of fatty liver by ultrasound were examined. Insulin resistance was estimated by calculating fasting insulin and glucose plasma level as the homeostasis model assessment (HOMA) index ratio. Data was described with mean ± SD and analyzed by independent sample t-test. Results: Thirty one patients were enrolled to the study, i.e. 8 patients with normal liver and 23 patients with fatty liver. Only 14 patients agreed to continue the study including 10 patients with fatty liver and 4 patients with normal liver. Mean of age was 59.1 ± 8.7 and mean value of BMI was 24.62 ± 3.05. The liver function test revealed normal Results. Triglyceride, cholesterol, fasting glucose level, and HOMA index (2.77 ± 1.95 vs. 1.66 ± 1.02) in patients with fatty liver were higher than patients with normal liver. No correlation was found between fasting insulin level as well as HOMA index and mean value of BMI (obese and non-obese) as well as hypertension. There was significant correlation between triglyceride level and fasting insulin among fatty liver patients (p = 0.048; CI 95% -7.404; -0.032). Conclusion: The non-alcoholic fatty liver disease in diabetic patients with normal liver enzymes and multiple oral hypoglycemic drugs appear to be related with insulin resistance and hypertriglyceridemia. Keywords: fatty liver, diabetic, insulin resistance
The Quality of Life of Patients with Liver Cirrhosis Hospitalized at Dr. Sardjito Hospital, Yogyakarta Sutanto Maduseno; Siti Nurdjanah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy VOLUME 3, NUMBER 2, August 2002
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/32200242-45

Abstract

Liver cirrhosis is a chronic and irreversible disease. The patients quality of life (QOL) may be impaired because of long-standing burden of the disease. This research was a cross-sectional study conducted at Dr. Sardjito Hospital, Yogyakarta to determined the QOL of patients with liver cirrhosis who hospitalized in this institution. The parameter for the QOL was measured according to Spitzer index. Sixty-five patients with liver cirrhosis of various etiology were abled to be studied. The number of male and female patients were almost equal (30 and 35 respectively). There was a reduction in QOL in both male (21/30) and female (28/35) but no significant different between this variable. There was a significant positive correlation between Child criteria, and nutritional status with QOL (r=0.68, p0.05 and r=0.37, p0.05). It was concluded that Child criteria and nutritional status were positively correlated with QOL.   Key words: Liver cirrhosis, quality of life, nutritional status
Karakteristik Kimia dan Fisik Beras Terserang Kutu (Sitophylus oryzae. sp): Chemical and physical characteristics of Rice Infested with lice (Sitophyllus oryzae. sp) Rani Juniarti; Samsu Udayana Nurdin; Siti Nurdjanah; Subeki; Udin Hasanudin
JURNAL AGROINDUSTRI HALAL Vol. 8 No. 2 (2022): Jurnal Agroindustri Halal 8(2)
Publisher : Lembaga Riset dan Pengabdian Kepada Masyarakat Universitas Djuanda Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/jah.v8i2.6741

Abstract

Rice (Oryza sativa) is susceptible to damage during storage including quantity and quality. Rice during storage for a long time will experience a decrease in quality both chemically and physically. This study was aims to determine the chemical and physical properties of rice attacked by lice (Sitophyllus oryzae sp). The experiment was arranged in a Randomized Completely Block Design (RCBD) with treatments in the form of samples of commercial rice, rice free of lice, rice attacked by lice. and by product of lice-attacted rice. The study consisted of 4 treatments with 6 replications. The data will be statistically tested using the SPSS 25 application. All data are further processed with the Least Significant Difference Test (BNT/LSD) at the 5% level. The chemical properties of rice infested with lice cause an increase in moisture content, lower protein content and total starch content. The physical properties of rice attacked by lice caused a decrease in water absorption, oil absorption and whiteness. The results showed that rice that was attacked by pests with moisture content of 13.23%, crude protein content 4.90%, total starch content 73.82%, water absorption capacity of 2.09 g/g, oil absorption capacity of 1.93 g/g and whiteness of 80.23.
Modification of Casava Starch Properties by Spontanesous Fermentation Neti Yuliana; Ica Dwi Kusuma Wardani; Dewi Sartika; Siti Nurdjanah
Jurnal Inovasi Teknologi Vol 4 No 1 (2023): April
Publisher : Engineering Forum of Western Indonesian Government Universities Board (Forum Teknik, BKS-PTN Wilayah Barat) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/jit.v4i1.5013

Abstract

The impact of spontaneous fermentation on the physical and chemical characteristics of fluidized cassava starch treated in a sedimentation tank were examined. Tapioka, aci puter, and elot are three types of casava starch products that were made from starch slurry collected at various periods of spontaneous fermentation. By different spontaneous fermentation time, the appearance of granules was significantly changed. Besides, there was diffrent response color to iodine test indicating a different amylopectin chain-length distribution pattern. Among them, there were significant differences in moisture content, swelling power, water absorption ratio, gel formation ability and pH value. These studies showed that spontaneous fermentation might be used to modify casava starch products.
FORMULASI TEPUNG DAUN KELOR (Moringa oleifera L.) DAN TEPUNG TERIGU TERHADAP MUTU SENSORI, FISIK, DAN KIMIA CUPCAKE Tri Okta Viani; Samsul Rizal; Siti Nurdjanah; Otik Nawansih
Jurnal Agroindustri Berkelanjutan Vol 2, No 1 (2023): JURNAL AGROINDUSTRI BERKELANJUTAN
Publisher : Jurusan Teknologi Hasil Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jab.v2i1.7191

Abstract

Cupcake daun kelor pada penelitian ini adalah cupcake yang berbahan baku tepung terigu dengan penambahan tepung daun kelor.  Tujuan penelitian adalah untuk mengetahui pengaruh formulasi tepung daun kelor dan tepung terigu terhadap mutu sensori, fisik, dan kimia cupcake mendekati SNI 01-4309-1996 tentang standar mutu kue basah.  Metode yang digunakan adalah Rancangan Acak Kelompok Lengkap (RAKL) dengan 4 ulangan menggunakan faktor tunggal yang terdiri dari 6 taraf formulasi tepung daun kelor dan tepung terigu yaitu P0 (0%:100%), P1 (5%:90%), P2 (10%:90%), P3 (15%:75%), P4 (20%:80%), dan P5 (25% :75%).  Data yang diperoleh dianalisis secara statistik dengan menggunakan uji Barlett dan Tukey dilanjutkan dengan uji ANOVA dan uji BNT pada taraf 5%.  Hasil penelitian menunjukan bahwa formulasi tepung daun kelor dan tepung terigu terbaik ditemukan pada perlakuan P1 (5%:95%) yang menghasilkan cupcake dengan kadar air sebesar 23,50%, kadar lemak sebesar 16,93%, kadar protein sebesar 16,35%, kadar karbohidrat sebesar 27,37%, kadar abu sebesar 1,35%, kadar serat kasar sebesar 5,40%, warna agak hijau, tekstur lembut, aroma tidak langu khas kelor, aftertaste yang tidak pahit, dan penerimaan keseluruhan yang disukai oleh panelis
Sus Kering Evaluasi Perbandingan Tepung Daun Kelor (Moringa oleifera) dan Tepung Terigu terhadap Sifat Fisik dan Sensori Sus Kering Lingga Kaila Azahra; Siti Nurdjanah; Novita Herdiana; Susilawati
Jurnal Agroindustri Berkelanjutan Vol. 4 No. 2 (2025)
Publisher : Jurusan Teknologi Hasil Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jab.v4i2.11520

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh perbandingan tepung daun kelor dan tepung terigu terhadap sifat fisik dan sensoris adonan choux pastry kering, serta mengidentifikasi perbandingan tepung daun kelor dan tepung terigu yang optimal untuk menghasilkan adonan choux pastry kering dengan sifat fisik dan sensoris terbaik. Penelitian disusun dalam Rancangan Acak Kelompok Lengkap (RAKL) nonfaktorial dengan 4 kali ulangan. Perlakuan perbandingan tepung daun kelor dan tepung terigu terdiri dari 6 taraf dengan konsentrasi sebagai berikut: P0 (0:100)g, P1 (1:99)g, P2 (2:98)g, P3 (3:97)g, P4 (4:96)g, dan P5 (5:95)g. Hasil penelitian menunjukkan bahwa perbandingan tepung daun kelor dan tepung terigu berpengaruh nyata terhadap sifat fisik, khususnya daya kembang dan densitas massa adonan choux pastry kering, serta sifat sensoris, meliputi warna, tekstur, rasa, dan aroma adonan choux pastry kering yang dihasilkan. Perlakuan terbaik untuk adonan choux pastry kering, P1 (1g tepung daun kelor : 99g tepung terigu), memiliki daya kembang 189,28%, berat jenis 0,130g/ml, skor warna 2,37 (kuning kecoklatan), skor tekstur 4,62 (renyah), skor rasa 4,37 (gurih), skor aroma 4,37 (agak harum, khas adonan choux pastry kering), kadar air 2,88%, kadar abu 3,37%, kadar lemak 25,30%, kadar protein 5,07%, kadar karbohidrat 63,38%, dan kadar antioksidan 33,35%. Adonan choux pastry kering dari perlakuan P1 menunjukkan tekstur, rasa, aroma, dan penerimaan keseluruhan yang lebih unggul, yang lebih disukai oleh panelis dibandingkan dengan adonan choux pastry kering tanpa menggunakan tepung daun kelor.