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All Journal Widyariset Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan Widyariset
Ekowati Chasanah
Balai Besar Penelitian dan Pengembangan Pengolahan Produk dan Bioteknologi Kelautan dan Perikanan
Aerospace Engineering Agriculture, Biological Sciences & Forestry Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Library & Information Science Materials Science & Nanotechnology Mechanical Engineering Neuroscience Physics

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Feasibility of metabolomic analysis in assessing coral reefs environments. Hedi Indra Januar; Boedi Hendrarto; Ekowati Chasanah
Squalen, Buletin Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 5, No 2 (2010): August 2010
Publisher : Research and Development Center for Marine and Fisheries Product Processing and Biotechnol

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/squalen.v5i2.45

Abstract

This study aimed to explain the feasibility of fingerprint and chemical marker metabolomicanalysis in assessment of coral reefs environments. Based on literature review, both analysismight be implemented on coral reef environment assessment, with their specific strength andweakness. Fingerprint metabolomic is a comprehensive approach in assessing the condition ofcoral reefs bioindicator that is having environmental stresses. It require high technology chemicalinstrumentation and complicated statistical approach in post data analysis. On the other hand,chemical marker metabolomic is more simplified in data analysis and instrumentation, but notcomprehensively assess the metabolite changes of bioindicator that is having environmentalstresses. To apply as high throughput screening in coral reefs assessment, subjectively the chemicalmarker method would be more feasible. One of the potential chemical marker that used iscembranoids, a bioactive compound from soft corals.
The potency of finding a new antimalarial drug from Indonesian sea Murtihapsari Murtihapsari; Ekowati Chasanah
Squalen, Buletin Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 5, No 3 (2010): December 2010
Publisher : Research and Development Center for Marine and Fisheries Product Processing and Biotechnol

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/squalen.v5i3.51

Abstract

Malaria is deadly disease killing 1.5-3 million peoples on the globe a year. In Indonesiaespecially Papua, malaria is a number one killer disease. Finding resources of new drug malariais seriously needed due to resistance to many Chloroquin by Plasmodium. About 65% of marinePorifera from 12 classes in the taxa have recently contributed to our knowledge of biomedicalmaterial. Sponges are abundantely inhabiting Indonesian waters. In recent discovery reportedthat marine sponge Xestospongiafrom Papua has possessed a great ability against Plasmodiumfalciparum.These evidence thus stated Indonesian water is home of the potential marine drug formalaria. For sustainable reason, production live specimen throughout sea culture should to behighlighted. This review presents a development of malaria disease and the potential of Indonesianmarine biota as biomedical material especially for malaria disease.
Development of enzymatically produced chitooligosaccharide from shrimp industrial waste: opportunity and challenge Ekowati Chasanah
Squalen, Buletin Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 5, No 2 (2010): August 2010
Publisher : Research and Development Center for Marine and Fisheries Product Processing and Biotechnol

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/squalen.v5i2.46

Abstract

Since identified having better properties such as solubility in water and bioactivities comparedto its polymer form, chitooligosaccharide has obtained great attention either from researcher andindustries. Wide application of chitooligosaccharides, from pharmaceutical, food and agriculture,is very depending on the deacetylation degree and the size of oligosaccharide. Enzymaticproduction is more dependable in producing specific, safe and environmentally friendlychitooligosaccharide. Chitosanase is one of chitin degrading enzymes group, having importantrole in production of chitooligosaccharide. Shrimp and crustacean waste which are abundant inIndones ia are important raw material for chitin and its deriv ativ e produc ts inc ludingchitooligosacharide and as a source of chitin degrading enzymes including chitosanase. RCMFPPBhas a c ollec tion of potential c hitin degrading mic robes for produc ing func tionalchitooligosaccharides for food, pharmaceutical and biocontrol applications. There is a bigopportunity for Indonesia as chitooligosaccharide producer as we have relatively big amount ofraw material from shrimp and crustacea’s waste, and local enzyme. One of the problem is thelegality of chitooligosaccharide for food and pharmaceutical products has not been available yet.Another non food application such as biocontrol can be developed first since this product does notneed strict regulation as for food.
Co-Authors Ariyanti Suhita Dewi Asri Pratitis Boedi Hendrarto Diini Fithriani Gintung Patantis Hedi Indra Januar M. Habbib Khirzin Miftahul Ilmi Muhammad Nursid Murtihapsari Murtihapsari Murwantoko . N.D. Yuliana Nuning Mahmudah Noor Nurrahmi Dewi Fajarningsih Rini Susilowati Subagus Wahyuono Subagus Wahyuono Sukarno Sukarno Thamrin Wikanta Wibowo Mangunwardoyo Yenny Risjani Yusro Nuri Fawzya