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All Journal Mutiara Medika: Jurnal Kedokteran dan Kesehatan JURNAL ILMIAH KOHESI
Oche Axena Yulhan
Universitas MUhammadiyah Sumatera Utara
Agriculture, Biological Sciences & Forestry Humanities Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Effects of AntiMycobacterium Tuberculosis Nanoherbal Legundy Leaf Extract (Vitex trifolia) Atika Dwiyanti; Siti Mulyani; Oche Axena Yulhan; Humairah Medina Liza Lubis; Ance Roslina
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 21, No 1 (2021): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v21i1.6497

Abstract

Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks 2nd largest in the world after India. Resistance to anti-tuberculosis drugs is one of the difficulties in treating tuberculosis. This research aim to determine the effectiveness of legundi (Vitex trifolia) leaf extract nanoherbal in killing Mycobacterium tuberculosis. This study was conducted with an experimental design using M. tuberculosis colonies taken from 25 samples of aspirate of tuberculosis patients with lymph nodes and then given the ethanol extract of legundi leaves (70% and 90%) with the process of making nanoparticle extracts. The evaluation of the observations was in the form of measuring the inhibition zone for bacterial growth which were categorized as weak (5mm), moderate (6-10mm), strong (11-20 mm) and very strong ( 21mm). The results of the study from 6 repetitions found that the inhibition zone category was 0% weak, 39% moderate, strong 52.3%, and very strong 8.7%. Comparison of the concentration of legundi leaf extract to the diameter of the bacterial growth inhibitory zone was analyzed using the Kruskal Wallis test, which found a significant relationship with p value = 0.000 (0.05). Legundi's leaf extract can be used as an antibacterial agent for M. tuberculosis. 
KUALITAS HIDUP ANAK DENGAN DOWN SYNDROME DI YAYASAN POTADS (PERSATUAN ORANG TUA ANAK DENGAN DOWN SYNDROME) JAWA BARAT OCHE AXENA YULHAN; ISRA THRISTY
JURNAL ILMIAH KOHESI Vol 5 No 3 (2021): JURNAL ILMIAH KOHESI
Publisher : LP2MTBM MAKARIOZ

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Abstract

Down syndrome is a congenital disorder characterized by an excess number of chromosome 21. Down syndrome affectsone in 700 births or one in 800-1,000 births and it is estimated that there are currently eight million people with DownSyndrome worldwide. A child with Down Syndrome is special because the excess chromosome results in changes of thephysical characteristics and intellectual abilities, as well as disturbances in physiological functions, which will affect thechild's independence and quality of life. To determine the quality of life in children with Down Syndrome based on age, sex,adaptive function, type of disease experienced, behavioral problems based on parental support. His study uses aquantitative descriptive method with a cross sectional design. The population in this study were all children with DownSyndrome who have joined the West Java POTADS (Parents Association of Children with Down Syndrome) foundation, withtotal of 300 people. This study shows that children with Down Syndrome aged 6-15 years have the lowest average quality oflife score on the feeling aspect (1.75) and the highest on the cognitive aspect (2.90). Quality of life for children with DownSyndrome can be seen from age, gender, parental support, as well as from children’s social and healt problem.
Co-Authors Ance Roslina Atika Dwiyanti Humairah Medina Liza Lubis Isra Thristy Siti Mulyani