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Tinjauan Ketepatan Penggunaan Oains Pada Pasien Reumotoid Arthritis Di Puskesmas Aur Duri Kota Jambi Tahun 2018 Jelly Permatasari; Lili Andriani; Yuli Mudia Sari
JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Vol 6, No 1 (2020): APRIL 2020
Publisher : Universitas Ubudiyah Indonesia

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Abstract

Reumotoid arthritis (RA) adalah penyakit autoimun yang terkait dengan kecacatan progresif, komplikasi sistemik dan kematian dini. OAINS digunakan sebagai terapi awal untuk RA, Penelitian ini termasuk penelitian jenis non-eksperimental, pengambilan data secara retrospektif. Hasil penelitian menunjukkan terdapat 132 sampel yang memenuhi kriteria inklusi dan eksklusi. Paling banyak digunakan adalah ibuprofen dengan jumlah 32,57%, tepat indikasi 100%, tepat dosis obat dengan jumlah 100%, tepat frekuensi obat dengan jumlah 100%, potensi interaksi obat tingkat keparahan minor 5,30%, tingkat keparahan moderat 32,57% dan tidak ada interaksi 62,12%. Dari 132 data pasien reumotoid arthritis di Puskesmas Aur Duri Kota Jambi, penggunaan OAINS sudah rasional. 
PENYULUHAN DAN DEMONSTRASI PENGOLAHAN AIR BERSIH PADA SUKU ANAK DALAM (SAD) LUBUK KAYU ARO Lili Andriani; Susi Widiawati; Yuliawati Yuliawati
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 2, No 2 (2019): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (378.626 KB) | DOI: 10.31604/jpm.v2i2.67-70

Abstract

The availability of clean water is a major human requirement. Suku Anak Dalam community communities often struggle to access clean water sources. The river becomes one of the sources of clean water used to meet the needs of water, but the condition of the river does not meet the standard for use. The purpose of this community devotion is to do clean water counseling and demonstration about the manufacture of water filter media in Suku Anak Dalam in Lubuk Kayu Aro, Mestong District of Muaro Jambi, Jambi. This activity will be expected to improve the health quality of the Suku Anak Dalam in Lubuk Kayu Aro. The method used was counseling to the community of Suku Anak Dalam in Lubuk Kayu Aro and did a demonstration of a simple water filter media. Materials needed include sieve containers, bottled water, gravel, palm-fiber, sand, and foam. The result of this community devotion is increasing public knowledge about the importance of clean water in life. In addition, people can know how to create water filter media and apply it in daily life. Keywords: clean water, Suku Anak Dalam, water filter media
Acute Toxicity LD50 Fraction Ethyl Acetate Aquilaria malaccensis, Ficus benjamina, Mikania micrantha, and Fraction Water Cinnamomum burmanii in Mus Musculus Rizky Yulion; Santi Perawati; Barmi Hartesi; Lia Anggresani; Lili Andriani; Lesra Indriani; Lara Syahila; Suci Ramadani; Nadia Monika
Biology, Medicine, & Natural Product Chemistry Vol 12, No 1 (2023)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2023.121.55-60

Abstract

Research on the acute toxicity of LD50 had been carried out on the ethyl acetate fraction of Gaharu leaves (Aquilaria malaccensis), beringin leaves (Ficus benjamina), sembung rambat leaves (Mikania micrantha), and kayu manis cortex (Cinnamomum burmanii) water fraction the base of use as traditional treatment by the Suku Anak Dalam (SAD) empirically obtained from ancestors. This research methodwas experimental and it used male and female mice. The control group was given a 1% NaCMC doses of 625 mg/kg body weight, 1,250 mg/kg body weight, 2,500 mg/kg body weight, and 5,000 mg/kg body weight. The test preparation was administered orally once per day. The Thomson-Weil method was used for the measurement of LD50 values. The weight ratio of organs was applied for heart, liver, lungs, kidneys, and stomach. The results showed that the LD50 value for male mice was 2454mg/kg body weight; 2454mg/kg body weight; 1546 mg/kg body weight and 2065mg/kg body weight respectfully. The LD50 value for female mice was a pseudo LD50. The value of the organ weight ratio in each sample showed P<0.05 values that were obtained in gaharu leaves in the liver and kidney organs (male); heart in females. Beringin leaves value P<0.05 lung organs (male). Sembung rambat leaves P<0.05 values of the heart, liver, and stomach organs (male); heart and stomach (female). Cinnamomum cortex value P<0.05 liver and stomach organs (male). The conclusions showed that the LD50 value of the ethyl acetate fraction of gaharu leaf, sembung rambat leaf, beringin leaf, and kayu manis cortex in male mice was slightly toxic, while in female mice it could not be counted.
Aktivitas sitotoksik daun ceremai Lili Andriani
Riset Informasi Kesehatan Vol 6 No 1 (2017): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

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Abstract

Latar Belakang : Daun ceremai (Phyllanthus acidus) mengandung flavonoid, saponin, tanin, dan steroid. Kandungan senyawa tersebut diduga memiliki aktivitas sitotoksik pada pengobatan kanker. Tujuan penelitian ini untuk menguji aktivitas sitotoksik daun ceremai. Metode : Untuk skrinning awal antikanker dilakukan uji aktivitas sitotoksik dengan metode Brine Shrimp Lethality Test (BSLT). Penelitian ini dilakukan dengan menguji aktivitas sitotoksik dari ekstrak etanol dan fraksi daun ceremai dengan menentukan besarnya nilai LC50 selama 24 jam. Hasil : Nilai LC50 tertinggi pada ekstrak etanol adalah sebesar 6,83 ppm, dan fraksi etil asetat adalah sebesar 8,27 ppm. Kesimpulan : Ekstrak etanol dan fraksi etil asetat memiliki aktivitas sitotoksik yang tinggi dibandingkan fraksi lainnya sehingga sangat aktif berpotensi sebagai antikanker.