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Leilani Lestarina
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Health Professions Medicine & Pharmacology

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Journal : Paediatrica Indonesiana

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Association between C-reactive protein levels and physical fitness in 7 to 9 year old children at poor elementary schools in Surakarta, Indonesia Lilisianawati Lilisianawati; Endang Dewi Lestari; Diana Mayasari Hadianto; Maria Galuh Kamenyangan Sari; Leilani Lestarina; Harsono Salimo
Paediatrica Indonesiana Vol 49 No 2 (2009): March 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (126.27 KB) | DOI: 10.14238/pi49.2.2009.75-81

Abstract

Background  Data  regarding inflammatory factors  in  children arenot  so  well developed  as  in adults. Higher levels  of  physical fitnessmay be helpful in modifying the low-grade inflammatory state  thatis  indexed  by  C-reactive protein (CRP) levels.Objective  To  evaluate the association  of  physical fitness with  CRPlevels in children  and  to identify the possible related factors.Methods  This  cross-sectional study was  conducted  at  poorelementary schools in Surakarta, Indonesia using a group  of  217underweight children aged from 7 to 9 years old. Physical fitnesswas assessed using a modified Harvard Step Test.  CRP  levels weremeasured using a high-sensitivity  assay.  The  association betweenphysical fitness and  CRP  level was assessed using linear regressionanalysis. Multivariate analyses were used to adjust covariates,and statistical analyses were performed using SPSS for Windowssoftware version 15.0.Results  Subjects were 48% female  and  52% male, and elevenchildren (5%) had a  CRP  level  >  5 mg/L. Mean fitness level  andCRP  level did not differ  by  age and gender. Fitness level was notinversely correlated with  CRP  (r=0.10,  P=0.14).  Physical fitnesswas significantly correlated with BMI  (r=0.14;  P=0.04),  physicalactivity  [0R=3.3  (95% CI  1.7  to 6.4)], and fat intake  [0R=0.5(95%  CI  0.2 to 0.9) ].Conclusion  These findings indicate  that  physical fitness  is  notinversely correlated to  CRP  levels in children. However, ourstudy reveased  an  association between high fat intake and lowphysical fitness as well  as  a significant association  betweenhigh physical activiry and physical fitness.
Effect of iron ... zinc fortified milk on iron status and functional outcomes in underweight children Endang Dewi Lestari; Saptawati Bardosono; Leilani Lestarina; Harsono Salimo
Paediatrica Indonesiana Vol 49 No 3 (2009): May 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (132.517 KB) | DOI: 10.14238/pi49.3.2009.139-148

Abstract

Background Iron and zinc are essential micronutrients duringschool-age period. Milk could be an alternative medium formineral fortification because it is consumed frequently bychildren.Objective To evaluate the effect of iron-zinc fortified milksupplementation on iron status and functional outcomes inunderweight children.Methods 44 2 underweight subjects aged 7-10 years attending 10primary schools in Jakarta and Solo were recruited in the study.Subjects who had chronic illnesses, severe anemia, thalassemiaor cow's milk allergy were excluded. Blood samples were analyzedto determine hemoglobin, serum ferritin and serum zinc. SerumCRP was measured in sub sampled subjects (n= 60). Subjectswere randomizedly allocated to receive iron-zinc fortified milk(n = 225) and standard milk (n = 217) for six months. The fortifiedmilk will provide additional6.3 mg iron and 1.5 mg zinc per day (2feeds). The main outcomes measured were iron status, cognitivefunction, growth, physical fitness and morbidity.Results Study groups were comparable at baseline. The fortifiedmilk group had better physical fitness score and exercise durationat baseline. Both milk supplementations reduced the prevalenceof anemia and iron deficiency. Fortified milk improved the speedprocessing score (P< 0.0001), height (P<0.0001) and sittingheight (P=O.Ol) significantly.Conclusion Supplementation of milk reduces the prevalence ofanemia and iron deficiency. Zinc-iron fortified milk gives positiveimpact on cognitive performance, growth, and physical fitness.
Co-Authors Andayani D. Eka Diana Mayasari Hadianto Endang Dewi Lestari Harsono Salimo Inge Permadhi Lestari E. Dewi Lilisianawati Lilisianawati Maria Galuh Kamenyangan Sari Samuel Oetoro Saptawati Bardosono Saptawati Bardosono Sri Sukmaniah