Eko Sulistijono
Department Of Pediactrics, Division Of Neonatology, Saiful Anwar General Hospital, Universitas Brawijaya, Jl. Veteran, Malang

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Journal : Pediatric Sciences Journal

Clinical features and neonatal outcomes of neonatus with mother suspected COVID-19 in Malang, Indonesia: a serial-cases, single-centre Brigitta Ida Resita Vebrianti Corebima; Eko Sulistijono; Setya Mithra Hartiastuti; Atiek Wulandari; Vanisia Hayu Firdayanti; Nisak Humairoh; Setya Trista Kusumawahyuni
Pediatric Sciences Journal Vol. 1 No. 1 (2020): (Supplementary)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (703.521 KB) | DOI: 10.51559/pedscij.v1i1.6

Abstract

Background: The COVID-19 pandemic has affected every facet of life, beginning with the first hours and days after birth, some have argued that the prudent course is to isolate infants from mothers with suspected or confirmed COVID-19. This serial-cases showed the neonate’s outcome with mother suspected COVID-19. Cases: Four neonates were born from mother with suspected or confirmed with COVID-19. The neonates were born with 7-9 APGAR score and within normal limit. All of the patients were discharged from the hospital after two days of isolation in the hospital with negative Nucleic Acid Test of SARS-CoV-2 results. Conclusion: The clinical characteristics of neonates and neonatal outcome appear very good, and these outcomes are achieved with intensive, active management, which might be the best practice in resuscitation, stabilization, bathing the baby before going to the isolation ward, and management the patient in the isolation ward
Good outcome of newborn septic arthritis with holistic treatment: a case report Muhammad Irvan Avandi; Brigitta Ida Resita Vebrianti Corebima; Eko Sulistijono; Talita Clarissa Sinatra
Pediatric Sciences Journal Vol. 2 No. 2 (2021): (Available online 1 December 2021)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (562.011 KB) | DOI: 10.51559/pedscij.v2i2.25

Abstract

Introduction: Septic arthritis (SA) is a serious joint infection associated with significant morbidity that can cause permanent damage with articular cartilage destruction, osteonecrosis, and lifelong deformities. Here we present a good outcome of newborn septic arthritis with prompt treatment. Case Presentation: A one-month-old boy was brought with swelling of both knee joints two weeks before admission. He has a history of preterm birth and was hospitalized in the Neonatal Intensive Care Unit (NICU) because of neonatal pneumonia and sepsis. Several days after treatment, he came with swollen on both knees, both knee joint synovial liquid and sputum culture showed Klebsiella pneumoniae. Magnetic Resonance Imaging (MRI) was found intra articular fluid and erosion of the epiphyseal cartilage suspect infection process. After establishing the diagnosis of SA, we initiated treatment with cloxacillin 60 mg/kgs body weight for 14 days. He underwent debridement and physiotherapist. One year after discharge, the physical examinations showed normal findings and had a normal gait. Conclusion: It can be concluded that prompt diagnosis and treatment of SA on the newborn will have a good outcome with no sequelae. An early diagnosis of SA can guide clinicians to initiate a standardized treatment and improve patient outcomes.
The correlation between levels of vitamin D (25(HD)D) and the occurrence of necrotizing enterocolitis (NEC) in preterm infants Eko Sulistijono; Brigitta Ida Resita Vebrianti Corebima; Yesi Adisti Pramitasari
Pediatric Sciences Journal Vol. 4 No. 1 (2023): (Available online: 1 June 2023)
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v4i1.48

Abstract

Introduction: One of the causes of gastrointestinal emergencies in newborns is necrotizing enterocolitis (NEC). A fetus is fully dependent on transfer from the mother as it lacks endogenous 25(OH)D production. Transplacental vitamin D transmission mainly occurs due to the elevated risk of vitamin D insufficiency in preterm newborns during the third trimester of pregnancy. This research is important to raise awareness about the importance of early initial screening of vitamin D levels in preterm infants in Indonesia. Methods: This study used an observational research design which is a cohort study, taking place during March–May 2020 in the neonatology inpatient ward of dr. Saiful Anwar General Hospital Malang. The enzyme-linked immunosorbent assay (ELISA) technique was used to measure the amount of vitamin D in the blood. The Kolmogorov-Smirnov test and the Levene test were used to determine whether the data were normal and homogeneous, respectively. Result: It was found that vitamin D levels in preterm infants with NEC were lower (10.18 ± 4.07 ng/mL) than in preterm infants without NEC (16.95 ± 4.45 ng/mL). The bivariate analysis result showed that vitamin D deficiency increased the risk of NEC by 10.7 times with p-value = 0.033 (95% CI 1.2-24.9). Furthermore, multivariate analysis found that vitamin D deficiency increased the occurrence of NEC by 19.4 times with a p-value = 0.043 (95%CI 0.7-21.7) and respiratory distress could increase the incidence of NEC by 9.4 times with a p-value =0.02 (95%CI 1.2-70). Conclusion: Vitamin D (25(OH)D) levels were lower in preterm infants with necrotizing enterocolitis compared to preterm infants without necrotizing enterocolitis. This study showed a significant correlation between vitamin D(25(OH)D) levels and the case of necrotizing enterocolitis in preterm infants.