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All Journal Proceeding International Conference on Global Resource Conservation Medical and Health Science Journal APPLICATION: Applied science in Learning Research
Zumrotul Mufidah
Bagian Klinik Hewan, Fakultas Kedokteran Hewan, Universitas Udayana, Bali
Education Health Professions Mathematics Physics Social Sciences Other

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The Immune Responses of DDY Mice infected S. aureus After Treatment of M. citrifolia Fruit Crude Extract Mufidah, Zumrotul; Rifa’i, Muhaimin; Rahayu, Sri
Proceeding International Conference on Global Resource Conservation Vol 4, No 1: Proceeding of 4th ICGRC 2013
Publisher : Proceeding International Conference on Global Resource Conservation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (0.209 KB)

Abstract

Infection disease that caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. One of the plants that can be used as medical herbal is Morinda citrifolia. The aim of this study is to know the immune response of mice with S. aureus infection by change to quantitatives’ lymphocytes and neutrophils after administration of M. citrifolia fruit crude extract. Mice were divided into two groups there are Non-Infection and infection. Non Infection is without S. aureus and than infection has S. aureus. The each groups are including control, dose 1 (25 mg/kg BW), dose 2 (100 mg/kg BW), and dose 3 (300 mg/kg BW). Oral treatment carried out for 20 days and injection of S. aureus at day 21 after with a concentration is 109 cell/ml. Relative number of neutrophil cell (Gr-1) and T cell subsets was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed using two way ANOVA (p<0.05). The result showed that administration of M. citrifolia crude extract was significantly changes in the relative amounts Gr-1+, CD4+, and CD8+ T cells.  Keywords: immunomodulators, Morinda citrifolia, Staphylococcus aureus  
JUMLAH RELATIF SEL NEUTROFIL (GR-1+) PADA MENCIT (MUS MUSCULUS) TERINFEKSI STAPHYLOCOCCUS AUREUS SETELAH PEMBERIAN EKSTRAK BUAH MENGKUDU (MORINDA CITRIFOLIA L.) Mufidah, Zumrotul
Jurnal Ilmu Kesehatan dan Kesehatan Vol 1 No 1 (2017): FEBRUARY
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v1i1.615

Abstract

Objective: The aim of this study was to determine the relative number of neutrophil (GR-1+) on miceinfected Staphylococcus aureus after treatment noni (Morinda citrifolia L.) crude extract. Methods: Micewere devided into two group: non-infected and infected. Non infected group was without S.aureus infectionwhereas the infected group was infected with S.aureus. Group contain kontrol, dose 1 (25 mg/kg BW), dose 2(100 mg/kg BW), and dose 3 (300 mg/kg BW). Oral treatment carried out for 20 days in every morning andeach sample was injected with S.aureus at day 21 with 109 cell/mL. Relative number of neutrophil (GR-1+)was measured using the BD FACSCaliburTM Flowcytometer. Data were analyzed by using Analysis ofVarians (p<0,05) and SPSS 16 for windows. Result: The result showed that administration of noni crudeextract was significantly change the relative number of neutrophil (GR-1+). Conclusion: Treatment of noni(M. citrifolia) crude extract could increase relative amount of neutrophil (GR-1+) on infected S.aureus andwithout infected group. That might be caused by active compound on noni crude extract that can influenceactivity of increasing Granulocyte Colony Stimulating Factor (G-CSF) so can increase relative amount ofneutrophil (GR-1+).
Students' Concept Understanding Through Four Tier Diagnostic Test In Fiqih Subject Of Class XI Madrasah Aliyah Safitri, Melina; Chotimah, Chusnul; Mufidah, Zumrotul; Putra, Ino Angga
APPLICATION: Applied science in Learning Research Vol. 3 No. 3 (2024): February
Publisher : LPPM Universitas KH. A. Wahab Hasbullah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32764/application.v3i3.4610

Abstract

The purpose of this study was to determine the students' conceptual understanding through the Four Tier Diagnostic Test in the Fiqh Subject of class XI MA Fattah Hasyim. This study uses descriptive quantitative research. Descriptive research attempts to describe an existing phenomenon, namely the implementation of the four-tier diagnostic test instrument in seeing students' misconceptions. The population and sample of the study used the Purposive Sampling Technique in Class XI F Language MA Fattah Hasyim with a total of 30 students. The collection of research data used the four-tier diagnostic test. This instrument consists of 15 validated questions. The research data were analyzed through normality tests and homogeneity tests. The results of the study of students' conceptual understanding through the four-tier diagnostic in the fiqh subject obtained a conceptual understanding of 74.89%, quite understanding 20.67%, weak concepts 1.11%, and misconceptions 3.33%. Students tend to experience misconceptions in the sub-material of gifts at number 9 with an average of 33.33%, then experience misconceptions again in the sub-material of grants at number 11 with an average of 10.00%, and in the sub-material of nafaqah and sadaqah numbers 1 and 8 with an average of 3.33%.
Students' Concept Understanding Through Four Tier Diagnostic Test In Fiqih Subject Of Class XI Madrasah Aliyah Safitri, Melina; Chotimah, Chusnul; Mufidah, Zumrotul; Putra, Ino Angga
APPLICATION: Applied science in Learning Research Vol. 3 No. 3 (2024): February
Publisher : LPPM Universitas KH. A. Wahab Hasbullah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32764/application.v3i3.4610

Abstract

The purpose of this study was to determine the students' conceptual understanding through the Four Tier Diagnostic Test in the Fiqh Subject of class XI MA Fattah Hasyim. This study uses descriptive quantitative research. Descriptive research attempts to describe an existing phenomenon, namely the implementation of the four-tier diagnostic test instrument in seeing students' misconceptions. The population and sample of the study used the Purposive Sampling Technique in Class XI F Language MA Fattah Hasyim with a total of 30 students. The collection of research data used the four-tier diagnostic test. This instrument consists of 15 validated questions. The research data were analyzed through normality tests and homogeneity tests. The results of the study of students' conceptual understanding through the four-tier diagnostic in the fiqh subject obtained a conceptual understanding of 74.89%, quite understanding 20.67%, weak concepts 1.11%, and misconceptions 3.33%. Students tend to experience misconceptions in the sub-material of gifts at number 9 with an average of 33.33%, then experience misconceptions again in the sub-material of grants at number 11 with an average of 10.00%, and in the sub-material of nafaqah and sadaqah numbers 1 and 8 with an average of 3.33%.
Co-Authors Chusnul Chotimah Ino Angga Putra Muhaimin Rifa’i Safitri, Melina SRI RAHAYU Wiwik Handayani