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All Journal Nexus Biomedika Indonesian Journal of Tropical and Infectious Disease Plexus Medical Journal
Dhani Redhono Harioputro
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Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health

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Profile Comparison of Patient with Staphylococcus epidermidis and Staphylococcus aureus on Blood Specimen at Dr. Moewardi Hospital Gani Dwi Cahya; Marwoto .; Dhani Redhono Harioputro
Nexus Biomedika Vol 5, No 2 (2016): Nexus Biomedika
Publisher : Nexus Biomedika

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Abstract

Introduction: Staphylococcus epidermidis and Staphylococcus aureus are some of bacteria that are often found in blood specimen. Unlike Staphylococcus aureus, which is true pathogen, Staphylococcus epidermidis is known as opportunistic bacteria which actually are normal flora of human skin. Therefore, it is necessary to have comparative data that can determine whether Staphylococcus epidermidis are cause of infection or just colonization. The purpose of this research was to compare clinical profile of patients with Staphylococcus aureus and Staphylococcus epidermidis found in blood specimen. Methods: This study was a descriptive research using clinical epidemiology approach. The objects of the research were patients medical records which had been identified by blood culture with positive result of Staphylococcus epidermidis and Staphylococcus aureus on 2014-July 2015. Sampling was held during November and December 2015 at Dr. Moewardi Hospital, Surakarta. Sampling was done and 65 people taken from the population. The data were analyzed with frequency odds ratio. Results: During January 2014 - July 2015, it was found that 36 subjects of patients with positive Staphylococcus epidermidis (21 men, 15 women) and 29 subjects of patients with positive Staphylococcus aureus (11 men, 18 women). Staphylococcus epidermidis was mostly found in newborns dan infants, while Staphylococcus aureus was mostly found in adults and elders. The result of white blood count and neutrophil percentage showed that patients with positive Staphylococcus aureus on their blood specimen have higher value than Staphylococcus epidermidis. Vital sign showed higher mean value of body temperature on patients with positive Staphylococcus aureus on their blood specimen than Staphylococcus epidermidis. Conclusion: There were differences in the increase of body temperature, number of leukocytes, and percentage of neutrophils in patients profile who were exposed to Staphylococcus aureus and Staphylococcus epidermidis on blood specimens at Dr. Moewardi Hospital. Keywords: Blood Specimen, Blood Culture, Staphylococcus aureus, Staphylococcus epidermidis
The Effect of C-Reactive Protein Levels, Neutrophil, and Lymphocyte Count to Mortality of COVID-19 Patients with Sepsis in Referral Hospital Malikhah, Avina Norma; Dhani Redhono Harioputro; Agung Susanto; Evi Nurhayatun
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 1 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i1.48634

Abstract

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by infection of Severe Acute RespiratoryDistress Syndrom Coronavirus-2 (SARS CoV-2). COVID-19 patients may develop sepsis, the disregulation ofthe immune system that causes organ dysfunction and life-threatening situations. High mortality of COVID-19and sepsis make it important to study. The purpose of this study is to analyze the effect of CRP levels, neutrophil,and lymphocyte count to mortality of COVID-19 patients with sepsis. This study is an analytic observational studywith a cross-sectional approach. Samples were randomly retrieved of COVID-19 patients with sepsis admittedin referral hospital. Univariate, bivariate, and multivariate analysis used SPSS 26th version of Windows. Theresults of this study indicate a significant effect of CRP levels and neutrophil count on mortality of COVID-19patients with sepsis. Meanwhile, lymphocyte count had no significant effects. The multivariate analysis showedits significance value. Partially, the effect of neutrophils on the patient's mortality has a significant value. Theconclusion of this study is CRP levels and neutrophil count simultaneously have an effect on higher mortality ofCOVID-19 patients with sepsis.
Hubungan HbA1c dan Asam Urat dengan Derajat Keparahan Disfungsi Ereksi pada Pasien Diabetes Melitus Tipe 2 di RSUD Dr. Moewardi Surakarta Gladera Wedpavica Zealtito Zulfan; Eva Niamuzisilawati; Arifin; Dhani Redhono Harioputro
Plexus Medical Journal Vol. 4 No. 3 (2025): Juni
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v4i3.1960

Abstract

Pendahuluan: Disfungsi ereksi merupakan salah satu komplikasi tersering pada pasien diabetes melitus tipe 2 yang sering dihubungkan dengan penyakit kardiovaskular. Mendeteksi dini potensi adanya disfungsi ereksi sebagai prediktor penyakit kardiovaskular penting dilakukan. Penelitian ini bertujuan mengetahui hubungan Hemoglobin A1c dan asam urat sebagai indikator dalam memberikan gambaran keparahan disfungsi ereksi. Metode: Penelitian cross-sectional terhadap pasien laki-laki dengan diabetes melitus tpe 2 di poliklinik endokrin Rumah Sakit Umum Daerah Dr. Moewardi. 32 sampel yang memenuhi kriteria inklusi mengisi kuesioner International Index of Erectile Function (IIEF-5) sebagai klasifikasi derajat disfungsi ereksi. Data diolah menggunakan uji Rank Spearman. Hasil: Tidak terdapat hubungan yang signifikan antara keparahan disfungsi ereksi dengan Hemoglobin A1c (p>0.05 dan r=0.347) dan asam urat (p>0.05 dan r=0.140) meskipun keduanya memiliki korelasi positif. Kesimpulan: Tidak terdapat hubungan yang signifikan antara Hemoglobin A1c dan asam urat dengan derajat keparahan disfungsi ereksi.
Co-Authors Agung Susanto Arifin Eva Niamuzisilawati Evi Nurhayatun Gani Dwi Cahya Gladera Wedpavica Zealtito Zulfan Malikhah, Avina Norma Marwoto .