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All Journal Jurnal Kedokteran Brawijaya Folia Medica Indonesiana Jurnal Klinik dan Riset Kesehatan
Sri Sunarti
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Nursing Public Health Other

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Effect of Long-Term Ketogenic Diet in Mice Serum Adiponectin Hamidah Kurniasari; Purwo Sri Rejeki; Hartono Kahar; Sri Sunarti
Folia Medica Indonesiana Vol. 58 No. 1 (2022): March
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (634.524 KB) | DOI: 10.20473/fmi.v58i1.30223

Abstract

Highlight:Adiponectin is an important protective factor for cardiovascular disease and increased insulin sensitivity.Ketogenic diet effect on adiponectin level in mice besides decrease weight gain was determined.The difference in serum adiponectin level and body weight is uncorrelated. Abstract:Ketogenic diet is a popular diet to reduce weight gain quickly. This diet has become a lifestyle . The ketogenic diet has been reported to affect adiponectin level, although it is still contraindicated. Adiponectin is a biomarker for metabolic disease that plays an important role as a protective factor for cardiovascular disease and increase insulin sensitivity. This study aimed to explore the effect of the ketogenic diet on adiponectin level in mice, besides decrease weight gain. This study was an experimental laboratory study with a randomized post-test-only control group design. Fourteen male mice (20-30 g) aged 2-3 months were divided randomly into K1 (n=7, standard diet) and K2 (n=7, ketogenic diet), were given diet for eight weeks, ad libitum. Body weight was measured at the pre and post-intervention, whereas adiponectin level were measured at the post-intervention using ELISA. The statistical analysis using SPSS version 16. The Shapiro Wilk test was used to determine normality, Independent T-Test was used to determine mean difference for normal distribution, Mann Whitney Test was used to determine mean difference for abnormal distribution, and Pearson Correlation was used to determine correlation. Difference (∆) of body weight on K1 (12.00±6.26) g, K2 (1.29±7.41) g with p=0.02. Serum adiponectin level of K1 (0.082±0.014) µg/ml and K2 (0.096±0.008) µg/ml with p=0.035. This study showed ketogenic diet-induced higher serum adiponectin level and slower weight gain. There is no correlation between the difference in body weight and serum adiponectin level (p=0.403).
Perceived Family Functionality among Elderly Patient with Covid-19 Infection: A Perspective from Developing Country Sri Sunarti; Didi Candradikusuma; Dewi Indiastari; Siti Fatma Prehatiningsih; Bogi Pratomo Wibowo; Affa Kiysa Waafi
Jurnal Kedokteran Brawijaya Vol. 32 No. 2 (2022)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2022.032.02.8

Abstract

Family is a basic social unit of senior citizen. Relationship among family members considered as source of emotional comfort. Meanwhile, economic, political, and social changes during pandemic has an impact on the family, the support provided can be manifested among vulnerable groups such as the elderly. Prolonged stress due to isolation care of Covid-19 infection increase psychological distress by reducing family support. This study aimed to explore perceived family function among elderly patients after Covid-19 infection. A cross sectional study was conducted among 33 elder patients with history of Covid-19 infection in Saiful Anwar General Hospital, Indonesia. Perceived family functionality was evaluated using APGAR family score. Data was analyzed using descriptive analyses, independent T test, correlation and regression. Mean total APGAR score was 9.610.70 with joint pain had significant association with APGAR score (p 0.021) indicating full family support in elder person with symptoms. Gender female was associated with 'Resolve' (p 0.038) which might correlate with bigger role of elder female in Indonesian family. Length of stay was significantly associated with 'Partnership' (p 0.012) and 'Growth' (0.043) with inverse correlation. It showed how prolonged hospital stay affected family relationship especially in terms of communication. Perceived family supports remained high in elderly during Covid-19 isolation in Indonesia. Specific symptoms such as joint pain, even strengthen the family support for elder member of family. Prolonged stay in the hospital during Covid-19 infection, might become a communication barrier between elder person and the family which affect decision sharing and emotional expression.
Perceptions and Experiences of Survivors of Mount Semeru Eruption in Getting Health Services during Covid-19 Pandemic Sri Sunarti; Aurick Yudha Nagara; Atma Gunawan; Marshanda Shella Pramesta; Fifi Afifatus Zakiya; Victoria Maya Kurniawati
Jurnal Kedokteran Brawijaya Vol. 32 No. 3 (2023)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2023.032.03.9

Abstract

Disaster events pose challenges for health workers in overcoming health problems in refugee camps. The eruption or hot clouds of Mount Semeru that occurred during the Covid-19 pandemic made sick survivors have to continue to receive health services, even though they were in refugee camps. Survivors' experiences in receiving health services and their illnesses varied widely. Perceptions of survivors in obtaining health services showed that most of them were well served and experienced a good referral system to higher-level hospitals. Home care was carried out by health workers to survivors after returning from refuges.
Insomnia pada Lansia: Tantangan dalam Mendiagnosis dan Pemberian Perawatan Siti Fatma; Sri Sunarti
Jurnal Klinik dan Riset Kesehatan Vol 2 No 2 (2023): Februari 2023
Publisher : RSUD Dr. Saiful Anwar Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.2.6

Abstract

Perubahan pola tidur pada usia lanjut sering terjadi, bisa sebagai proses fisiologis atau merupakan bagian dari penyakit kronis tertentu. Insomnia adalah salah satu gangguan yang paling banyak dikeluhkan oleh pasien usia lanjut, dan dipengaruhi oleh beberapa faktor seperti perubahan fisiologis, kebiasaan tidur, adanya penyakit – penyakit komorbid, juga bisa karena efek samping obat – obatan yang dikonsumsi. Untuk itu diperlukan skrining tersendiri agar bisa melakukan penilaian klinis komprehensif pada pasien usia lanjut seperti gangguan tidur primer, penyakit komorbid, gangguan mental seperti depresi dan cemas. Penatalaksanaan insomnia ini merupakan tantangan tersendiri dalam diagnosis dan terapi karena dibutuhkan perawatan komprehensif meliputi perubahan gaya hidup, kontrol penyakit komorbid, dan juga manajemen efek samping obat, sehingga nantinya bisa ditentukan terapi yang paling tepat dan efektifitas obat yang optimal.
Co-Authors Affa Kiysa Waafi Atma Gunawan Aurick Yudha Nagara Bogi Pratomo Wibowo Dewi Indiastari Didi Candradikusuma Fifi Afifatus Zakiya Hamidah Kurniasari Hartono Kahar, Hartono Marshanda Shella Pramesta Rejeki, Purwo Sri Siti Fatma Siti Fatma Prehatiningsih Victoria Maya Kurniawati