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All Journal Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease The Indonesian Biomedical Journal Sari Pediatri Jurnal Teknologi Laboratorium THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Care : Jurnal Ilmiah Ilmu Kesehatan Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indian Journal of Forensic Medicine & Toxicology Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Journal of Livestock and Animal Health (JLAH) Jurnal Medis Umum

Hartono Kahar, Hartono

Departemen Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Airlangga, Surabaya

Author-ID : 3212187

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Education Environmental Science Health Professions Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary Other

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PERBEDAAN KADAR TRIGLISERIDA PADA PENGKONSUMSI KOPI DAN BUKAN PENGKONSUMSI KOPI Kahar, Hartono
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Edisi 3: The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

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PERBEDAAN KADAR TRIGLISERIDA PADA PENGKONSUMSI KOPI DAN BUKAN PENGKONSUMSI KOPIÂ Dr. dr. Hartono Kahar, Sp.PK. MQIH. Prodi D3 Analis Kesehatan UM SurabayaÂ AbstractCoffee is a beverage that is loved by the people of Indonesia. Coffee can increase LDL and triglycerides (Royyak, 2010). Triglycerides are a type of lipid (fat) found in the blood. When we eat, our bodies change partially unused calories into triglycerides. Triglycerides are stored in the fat cells of the body, if stored too long will be cholesterol and accumulate in the blood vessels, causing constriction of blood vessels and increase the risk of heart attack. Formulation of the problem in this study is Are there differences in the levels of triglycerides in coffee drinkers and non-coffee drinkers ?. The purpose of this study to determine differences in triglyceride levels in coffee drinkers and non-coffee drinkers. Type of research is observational with a total sample of 30 samples. 15 samples for coffee drinkers and 15 samples for non-coffee drinkers. Samples are healthy people who are accustomed to consuming coffee and rarely consume coffee every day. Types of coffee are consumed coffee mashed. The results showed average levels of triglycerides in the coffee drinkers of 245 mg / dl and the average levels of triglycerides in non-coffee drinkers of 113.33 mg / dl. Statistical analysis using the t-test showed that the levels of triglycerides free at coffee drinkers was higher than non-coffee drinkers.Â Keyword : coffea, LDLÂ Â Â

HUBUNGAN JUMLAH EOSINOFIL DENGAN INFEKSI LARVA CACING TAMBANG PADA PENAMBANG PASIR DI DS. BRENGGOLO KECAMATAN KALITIDU BOJONEGORO. kahar, hartono
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Edisi 1: The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

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HUBUNGAN JUMLAH EOSINOFIL DENGAN INFEKSI LARVA CACING TAMBANGÂ PADA PENAMBANG PASIR DI DS. BRENGGOLO Â KECAMATAN KALITIDU BOJONEGORO.Â Dr.dr. Hartono Kahar, Sp.PK., MQIH.Â Prodi D3 Analis Kesehatan UM SurabayaÂ AbstractÂ Eosinophils are white blood cells that play a role of granulocytes in the category of the immune system to fight infections and some multicellular parasites on vertebrate creatures. Eosinophils also control the allergic mechanism in the bone marrow, eosinophils will enter the bloodstream and stay in the blood only a few hours, then go into the tissues throughout the body. If a foreign substance enters the body, it would be detected by lymphocytes and neutrophils, which will release the material to attract eosinophils into this area. Eosinophils that occurs in miners exposed to infectious worm larvae will release toxic substances that can kill parasites or worms mines and destroy abnormal cells.The purpose of this study is to determine the relationship of the number of eosinophils with hookworm larvae infection in sand miners in the village. Brenggolo District Kalitidu Bojonegoro. This research uses analytic correlational design using cross sectional (relationships and associations). The number of samples is 49 miners in Ds. Brenggolo Kalitidu Bojonegoro District. By using a random sampling technique ie by random sampling without regard to strata that exist in members of the population.The survey results revealed most of the sand miners eosinophils increased by (44.9%) miners and miners sand worm larvae as much positive (55.1%) miners. Chi Square test calculation results with SPSS statistical test obtained obtained hasi p = 0, the count X2 = 0.000 <a = 0.05, which means that H0 is rejected. Thus it can be said there is a relationship eosinophil count against worm larvae on the sand miners in the Village District Brenggolo Kalitidu Bojonegoro.Â Keyword : Eosinophils, hookworm larvae infection

PERBEDAAN KADAR KETON URIN PADA PEMERIKSAAN SEGERA DENGAN PEMERIKSAAN YANG DITUNDA Kahar, Hartono
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Edisi 4: The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

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PERBEDAAN KADAR KETON URIN PADA PEMERIKSAAN SEGERA DENGAN PEMERIKSAAN YANG DITUNDAÂ Dr. dr Hartono Kahar, Sp.PK. MQIHÂ Prodi D3 Analis Kesehatan UNMUH SurabayaÂ AbstractUrine examination is a common examination done by a health care analyst at the laboratory. From the results of this examination can know about kidney disorders, urinary tract and some metabolic functions of the body. The length of delay in the laboratory examination of urine greatly affect the results of the analysis, it is because some of the content in the urine may change in case of delay in the examination, such as ketones. The volatile nature of the ketone, the urine is used fresh urine. In clinics and hospitals in general, there is still a delay examination of the urine. Formulation of the problem in this study is whether there are differences in levels of ketones urine examination on examination with the examination immediately suspended, while the purpose of this study to investigate the influence of long delays on the results of urine ketone levels. The hypothesis of this research is that there are differences in levels of ketones in the urine examination with the examination immediately suspended. The research method used was experimental. The population of this research is all the urine that has been available in hospital laboratories Pamekasan district that has shown positive results ketones with accidental sampling technique. The variable in this study was the examination time and urine ketone levels with a sample of 16 urine samples. From the results of the study with a 30-minute time delay obtained 14 urine samples (87.5%) with high levels of ketones and 2 negative urine samples (12.5%) with very low levels of ketones. From the results of these data, wilxocon tested and the results obtained with a value of Z = -3.624 significant value 0.000 <0.05 or 5%, so it can be concluded that there are differences between the levels of ketones urine samples examined immediately by a delayed.Key word : Urine examination, ketones

PENINGKATAN MUTU PEMERIKSAAN DI LABORATORIUM KLINIK RUMAH SAKIT Kahar, Hartono
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol 12, No 1 (2005)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v12i1.839

Clinicians always needs the results of clinical laboratory with quality assurance. The performance of good quality laboratory depends on pre-analytic, analytic as well as post analytic processes. It is also influenced by reagents and methods types as well as personal laboratory work. The goal of laboratory examinations quality runs between QMS, or Five Q’s, which consist of: Quality planning, laboratory practice, control, and assurance and Quality improvement. The quality laboratory examinations depend on the accuracy and precision results.

Chymase Level in Dengue Virus Infection With or Without Positive Non-Structural 1(NS1) Kasiyati, Menik; Nugraha, Jusak; Kahar, Hartono
Jurnal Teknologi Laboratorium Vol 8 No 2 (2019): 2019 (2)
Publisher : POLTEKKES KEMENKES YOGYAKARTA

Thrombocytopenia, leukopenia, and monocytosis are laboratory parameters in the diagnosis of dengue virus infection. In addition to monocyte cells, mast cells also play a role in the innate immune response, where degranulation of mast cells will occur, which will secretion the active vaso mediator, Chymase. Chymase has a role in increasing vascular permeability resulting in plasma leakage in patients with dengue virus infection to determine the number of platelets, leukocytes, monocytes and chymase levels in patients with dengue infection in the acute phase. The platelet count mean in NS1 (+) was 132,140 cells / mm3 and the platelet count in the NS1 group was (-) 176,000 cells / mm3. The mean leukocytes NS1 (+) showed results of 4,350 cells / mm3 and NS1 (-) 5,250 cells / mm3. The mean monocyte NS1 (+) monocyte count was 8.26%, and NS1 (-) group was 8.76%. There were no significant differences in platelet counts, leukocytes and monocytes between NS1 (+) and NS1 (-) (P value> 0.05). The mean Chymase NS1 (+) 23.48, NS1 (-) 23.05 ng / mL and the control group 1.47ng / mL.

Inhibitors in Hemophilia A with Posterior Dextra Femoral Region Hematoma Malfira Iswary; Hartono Kahar
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16955

Pengaruh Hemolisis Terdapat Kadar Serum Glutamate Pyruvate Transaminase (SGPT) Sebagai Salah Satu Parameter Fungsi Hati hartono kahar
THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Vol 1, No 1 (2018): The Journal of Muhammadiyah Medical Laboratory Technologist
Publisher : Universitas Muhammadiyah Surabaya

AbstractSGPT examination is one of the important checks on the state of a particular patient, for example, in patients with liver disease, hepatitis, and so forth. The other purpose is to detect the presence of liver damage. So there was an effect in the event of an increase in maupaun drop in levels. And the serum circumstances that do not qualify, such as serum hemolysis, will greatly affect the actual levels of ALT. Based on the research background, the authors formulate the problem as follows: "Is there any effect of hemolysis on SGPT levels as one of the parameters of liver function?". The purpose of this study is to prove whether there is an influence of hemolysis on SGPT levels as one of the parameters of liver function. The sample was 20 samples and 20 samples of hemolysis hemolysis. Location and time of the research conducted at Muhammadiyah Hospital Clinical Laboratory Lamongan ie in January and July. Of the 20 samples analyzed, showing that levels higher than the hemolysis ALT SGPT levels no hemolysis. When the serum through lysis will experience a significant increase. To test the effect of hemolysis on SGPT levels paired t test was used because the data from this study with normally distributed. The results of a paired t test analysis between serum hemolysis and no hemolysis on levels of serum ALT levels showed a significant value 0.00 thus P <0.05 it can be concluded that there is no difference between the levels of ALT SGPT levels of hemolysis with hemolysis. That means there is the influence of hemolysis on SGPT levels as one of the parameters of liver function. Key word : hemolysis, glutamate pyruvate transminase

Thrombocyte Count in Male and Female Adult of Dengue Hemorrhagic Fever Patients Lelyana Sih Afgriyuspita; Heny Arwati; Hartono Kahar
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.3559

AbstractThe trend of dengue virus infection in Indonesia has changed from children to older groups. Some studies suggested that different gender might affect the different progression of dengue infection, but its mechanism was unclear. This study analyzed the difference by evaluating the daily thrombocyte count pattern. An analytic observational study with a retrospective design was conducted using the secondary data collected from medical records in Dr. Soetomo General Hospital Surabaya during 2017-2018. The samples were adult patients in the age range of 18-55 years old with DHF but without comorbidity or coinfection. The total number of samples was 40 patients. The average of thrombocyte count in both male and female patients decreased since the 3rd day of illness and reached the lowest level on the 6th day of illness then increased on the 7th day but did not reach the normal range. Although the majority of thrombocyte count in females was lower than males, there was no significant difference in thrombocyte count pattern between them. Keyword: Adult, DHF, Thrombocyte, GenderCorrespondence : heny-a@fk.unair.ac.id

Pola Jumlah Trombosit Pasien Infeksi Virus Dengue yang dirawat di SMF Ilmu Kesehatan Anak RSUD Dr. Soetomo Surabaya Rizkiya Candra Sari; Hartono Kahar; Dwiyanti Puspitasari
Sari Pediatri Vol 19, No 1 (2017)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Latar belakang. Dengue merupakan penyakit infeksi virus akut yang sering menimbulkan morbiditas dan mortalitas tinggi di Indonesia. Trombositopenia merupakan salah satu parameter laboratorium dalam penegakan diagnosis infeksi virus dengue yang dapat berubah dari hari ke hari.Tujuan. Mengetahui pola jumlah trombosit pada anak terinfeksi virus dengue untuk meningkatkan pemahaman dan kewaspadaan terhadap kondisi pasien.Metode. Penelitian retrospektif analitik pada pasien dengue fever (DF) dan dengue haemorrhage fever (DHF) yang dirawat di SMF Ilmu Kesehatan Anak RSUD Dr. Soetomo Surabaya periode Januari-Juni 2015. Data jumlah trombosit, hari sakit, diagnosis, dan karakteristik penderita diambil dari rekam medis dan dianalisis menggunakan independent sample t-test.Hasil. Rerata trombosit pasien DF mulai turun pada hari sakit ke-4. Terendah pada hari sakit ke-5 dan kembali naik pada hari sakit ke-6. Rerata trombosit pasien DHF menurun mulai hari sakit ke-3. Terendah pada hari sakit ke-5 dan meningkat pada hari sakit ke-6. Rerata trombosit pasien DHF dengan syok hari sakit ke-3 adalah 52.382 sel/mm3 dan rerata terendah pada hari sakit ke-6 (40.815 sel/mm3) dan mulai meningkat pada hari sakit ke-7. Terdapat perbedaan bermakna rerata trombosit DF dan DHF pada hari sakit ke-3,4,5,6 (p<0,001) dan ke-8 (p=0,012). Perbedaan rerata trombosit pasien DHF dengan dan tanpa syok bermakna pada hari sakit ke-6 (40.815 sel/mm3 dan 68.589 sel/mm3, p=0,004).Kesimpulan. Terdapat perbedaan yang bermakna pada rerata trombosit pasien DF dan DHF. Penurunan trombosit <100.000 sel/mm3 pada hari sakit ke-3 harus lebih diwaspadai agar tidak jatuh pada kondisi syok yang lebih buruk.

Effect of Long-Term Ketogenic Diet in Mice Serum Adiponectin Hamidah Kurniasari; Purwo Sri Rejeki; Hartono Kahar; Sri Sunarti
Folia Medica Indonesiana Vol. 58 No. 1 (2022): March
Publisher : Universitas Airlangga

Highlight:Adiponectin is an important protective factor for cardiovascular disease and increased insulin sensitivity.Ketogenic diet effect on adiponectin level in mice besides decrease weight gain was determined.The difference in serum adiponectin level and body weight is uncorrelated. Abstract:Ketogenic diet is a popular diet to reduce weight gain quickly. This diet has become a lifestyle . The ketogenic diet has been reported to affect adiponectin level, although it is still contraindicated. Adiponectin is a biomarker for metabolic disease that plays an important role as a protective factor for cardiovascular disease and increase insulin sensitivity. This study aimed to explore the effect of the ketogenic diet on adiponectin level in mice, besides decrease weight gain. This study was an experimental laboratory study with a randomized post-test-only control group design. Fourteen male mice (20-30 g) aged 2-3 months were divided randomly into K1 (n=7, standard diet) and K2 (n=7, ketogenic diet), were given diet for eight weeks, ad libitum. Body weight was measured at the pre and post-intervention, whereas adiponectin level were measured at the post-intervention using ELISA. The statistical analysis using SPSS version 16. The Shapiro Wilk test was used to determine normality, Independent T-Test was used to determine mean difference for normal distribution, Mann Whitney Test was used to determine mean difference for abnormal distribution, and Pearson Correlation was used to determine correlation. Difference (∆) of body weight on K1 (12.00±6.26) g, K2 (1.29±7.41) g with p=0.02. Serum adiponectin level of K1 (0.082±0.014) µg/ml and K2 (0.096±0.008) µg/ml with p=0.035. This study showed ketogenic diet-induced higher serum adiponectin level and slower weight gain. There is no correlation between the difference in body weight and serum adiponectin level (p=0.403).

Co-Authors Afgriyuspita, Lelyana Sih Agustiningrum, Indah Ambar, Nabil Salim Arifoel Hajat Betty Agustina Tambunan Biutifasari, Verna Dachlan, Yus Prijatna Djatiwidodo Edi Pratiknya Dwiyanti Puspitasari, Dwiyanti Elly Sulistyani Engki Zelpina Hamidah Kurniasari Harida Zahraini Heny Arwati Hermawan, Intan Permatasari Hildegardis Dyna Dumilah Jelita Aprisano Putri Jusak Nugraha Kasiyati, Menik Kusuma, Edward Putra Lelyana Sih Afgriyuspita M. Robiul Fuadi Malfira Iswary Muhamad Reza Utama Nabilla Feirizky Chairunnisa Ni Komang Sri Dewi Untari Nur Vita Purwaningsih, Nur Vita Palestin Pramita Anindya Nugraheni Rahma Widyastuti Rejeki, Purwo Sri Rizkiya Candra Sari Ronald Pratama Adiwinoto S.Pd. M Kes I Ketut Sudiana . Setiawan, Philia Shinta Lungit Ambaringrum Soebroto, Heroe Sri Sunarti Tito Yustiawan Tri Ade Saputro Vella Rohmayani Vendra Setiawan Waras Budiman Wardhani, Hana Yetti Hernaningsih Yulia Nadar Indrasari Zubir Zubir

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