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Antidiabetic Activity Of Barley Porridge On Postprandial Blood Glucose And Histopathology Of Alloxan-Induced Diabetics Rats Celin Celin; Meldawati Meldawati; Yeni Halim
Eduvest - Journal of Universal Studies Vol. 4 No. 11 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i11.39006

Abstract

Diabetes mellitus (DM) is a critical global health issue, characterized by high morbidity and mortality rates associated with various complications. In Indonesia, the incidence is projected to reach 28.6 million by 2045, positioning the country among the highest globally. The aim of this study is to evaluate the effects of barley as a food ingredient on blood sugar levels and pancreatic histopathology. The study involved dividing the mice into six groups, with six mice in each group. These groups were: normal control (K), negative control (KN) induced with alloxan 125 mg/kg BW intraperitoneally, positive control (KP) with oral metformin 9 mg/200 g BW, normal barley rats (P1), DM barley rats (P2), and DM rats with mixed food (P3). Phytochemical screening was also conducted on barley porridge to identify the presence of flavonoids, glycosides, alkaloids, and saponins. The KP and P2 groups were more effective in reducing blood sugar levels than the KN and P3 groups. In the Kruskal-Wallis test, there was no significant difference between groups P2 and KP on postprandial blood sugar levels, indicating that barley produced an effect similar to metformin (p-value = 0.0395). Pancreatic histopathology observations showed that groups P2, P3, and KP had the same damage score of 2. Barley demonstrated a comparable antidiabetic effect to metformin, as evidenced by similar results in blood sugar reduction and pancreatic histopathology scores in the P2 and KP groups
The Relationship of Stress to Blood Pressure and Body Mass Index in Pharmacy Study Program Students at Prima Medan University Kristina Sirait; Meldawati Meldawati; Yeni Halim; Muhammad Aji Al-Faris
Eduvest - Journal of Universal Studies Vol. 4 No. 11 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i11.49919

Abstract

Increased levels of academic stress in students can affect physical health, such as blood pressure and Body Mass Index (BMI). This study aims to determine the relationship between academic stress and blood pressure and BMI in Pharmacy Study Program students at Prima Indonesia University. This study used an analytical observational approach with a cross-sectional design, involving 4th semester students as research samples. Data were collected through the Perceived Stress Scale (PSS-10) questionnaire and measurement of blood pressure and BMI. Data were analyzed using Spearman's rho correlation test. The results showed a significant relationship between stress and blood pressure with a p-value of 0.029, but there was no significant relationship between stress and BMI with a p-value of 0.524. In conclusion, although there is a relationship between stress and blood pressure, stress levels are not directly related to BMI in university students. This study is expected to provide insight into the importance of stress management for student health.