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All Journal Budapest International Research in Exact Sciences (BirEx Journal) Britain International of Exact Sciences Journal (BIoEx Journal)
Colette Masengo Ashande
Department of Environmental Sciences, Faculty of Science, University of Gbado-Lite, Gbado-Lite, Democratic Republic of the Congo
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Mathematics Medicine & Pharmacology Physics Transportation

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TLC Profiling of Leaves Extracts of Some Aloe Threatened Species Endemic to Madagascar for Their Antioxidant Activity Rokiman Letsara; Rigobert Andrianantenaina; Gédéon Ngiala Bongo; Colette Masengo Ashande; Mahendra Ilmi S Matondang; Koto-te-Nyiwa Ngbolua; Baholy Robijaona Rahelivololoniaina
Britain International of Exact Sciences (BIoEx) Journal Vol 2 No 3 (2020): Britain International of Exact Sciences Journal, September
Publisher : Britain International for Academic Research (BIAR) Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/bioex.v2i3.304

Abstract

The World Health Organization reported that at least 80% of populations rely on traditional medicine and medicinal plants for their primary health care. Due to their phytochemical compounds, the plants of the Aloe genus are reported to have high potential antiCovid-19 (and antioxidant properties. The aim of this study is to evaluate the in vitro antioxidant activity of some Malagasy endangered species of Aloe genus. The ethanolic extract of few Aloe of Madagascar leaf extracts was fractionated by liquid-liquid partition using hexane. In total 18 different fractions from 9 species have been used to determine their antioxidant activity through in vitro model by using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay. Both hexanic extract and aqueous extract displayed antioxidant activities in four species. The most evident antioxidant activity was expressed by A. helenae.
Effect of Cassava (Manihot esculenta Crantz: Euphorbiaceae) Starch on the Stabilization of Malagasy Lateritic Soil Harinivo Olsynthique Razanajatovo; Serge Ravelomanantsoa; Elise Octavie Rasoazanany; Aristote Matondo; Colette Masengo Ashande; Muhammad Ridwan; Koto-te-Nyiwa Ngbolua; Robijaona Rahelivololoniaina Baholy
Budapest International Research in Exact Sciences (BirEx) Journal Vol 2, No 4 (2020): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v2i4.1261

Abstract

Laterite is one of the most widespread raw materials, especially in Madagascar. Its valorization as a building material would help to solve many socio-economic problems in Madagascar as well as in Africa. The use of this type of material fits well within the framework of high environmental quality, since the process uses an abundant material that does not require too much energy for its manufacture because it is dried in the open air. The aim of this work was to stabilize the laterite with cassava starch. The valorization of the latter would contribute to the development of new building materials. The study focuses on the mechanical characterization of specimens made with Vontovorona laterite in different proportions, which goes hand in hand with the determination of the physico-chemical parameters of the starch. To make specimens, we used techniques such as extraction, sieving, heating, laterite-stabilizing dosage, mixing, rotting, moulding, clamping, demoulding, drying. The results obtained show that the best stabilizing material is obtained if 15% of starch is mix to lateritic soil. The compressive strength in the dry state of the test specimens (samples) gave a significantly interesting result with a value of 54.8 bars (85% laterite with 15% starch). Thus the use of starch as a stabilizer in construction gave satisfactory results. This eco-friendly process, simple in its steps and practice, should be popularized among artisanal brick makers. Thus, replacing proportions of the Portland cement in soil stabilization with Cassava starch will reduce the overall environmental impact of the stabilization process. 
Acute Toxicity Evaluation of the Malagasy Endemic Aloe helenae and A. analavelonensis in Mice Rokiman Letsara; Rigobert Andrianantenaina; Colette Masengo Ashande; Clarisse Falanga Mawi; M. Yoserizal Saragih; Koto-te-Nyiwa Ngbolua; Baholy Robijaona Rahelivololoniaina
Budapest International Research in Exact Sciences (BirEx) Journal Vol 2, No 4 (2020): Budapest International Research in Exact Sciences, October
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birex.v2i4.1259

Abstract

The therapeutic virtues of medicinal plants are known and used in Africa and in Madagascar where natural products form the basis of Traditional Medicine. More than 300 million people worldwide consume dietary supplements and herbal plants. Scientific studies confirm that Aloes contains pharmacologically active ingredients associated with diverse biological activities including fungicidal, antiviral, antibacterial, anti-inflammatory, antimicrobial, laxative, immunomodulating, and anticancer effects. The aim of the present study was to evaluate the effects of orally administered extracts of two Aloe species: A. helenae, A. analavelonensis on mice. Mice were gavaged with crude whole leaves extracts after 24 hours of empty stomach. The extracts administration was found to be not acute toxic at the dose 1200 mg/kg with 100% survival of mice. Since the Aloe helenae is traditionally used against intestinal worms in sheep and goats, it is thus desirable that the plant species could be submitted to phytochemical for the isolation and characterization of new antihelminthic compounds.
Co-Authors Aristote Matondo Baholy Robijaona Rahelivololoniaina Baholy Robijaona Rahelivololoniaina Clarisse Falanga Mawi Elise Octavie Rasoazanany Gédéon Ngiala Bongo Harinivo Olsynthique Razanajatovo Koto-te-Nyiwa Ngbolua Koto-te-Nyiwa Ngbolua M. Yoserizal Saragih Mahendra Ilmi S Matondang Muhammad Ridwan Rigobert Andrianantenaina Rigobert Andrianantenaina Robijaona Rahelivololoniaina Baholy Rokiman Letsara Rokiman Letsara Serge Ravelomanantsoa