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All Journal Indonesian Journal of Cardiology Heart Science Journal
Habibie Arifianto
Unknown Affiliation
Health Professions Immunology & microbiology Medicine & Pharmacology

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Cardiovascular Complications In COVID 19 Infection Dian Yaniarti Hasanah; Siti Elkana Nauli; Vebiona Kartini Prima Putri; Habibie Arifianto; Nana Maya Suryana; Lita Dwi Suryani; Wahyu Aditya; Paskariatne Probodewi
Jurnal Kardiologi Indonesia Vol 41 No 2 (2020): Indonesian Journal of Cardiology: April - June 2020
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.994

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) yang dikenal dengan COVID-19 adalah penyakit yang baru dan telah menyebar dengan cepat dari Wuhan (provinsi Hubei) ke provinsi lain di Cina dan seluruh dunia termasuk Indonesia. Secara umum, COVID-19 adalah penyakit akut yang bisa sembuh tetapi juga mematikan, dengan case fatality rate (CFR) sebesar 4%. Spektrum klinis pneumonia COVID-19 berkisar dari kondisi ringan sampai dengan berat. COVID 19 diduga memiliki risiko potensiasi proses patofisiologi terhadap timbulnya komplikasi kardiak, dan telah diketahui bahwa mekanisme penyakit kardiovaskular serupa dengan mekanisme jalur imunologi. Penyakit kardiovaskular adalah komorbid terbanyak pada pasien COVID 19, SARS, dan MERS. Prevalensi diabetes mellitus (DM) dan penyakit kardiovaskular pada SARS adalah 11% dan 8% dan membawa angka kematian meningkat 2 kali lipat. Pada kasus COVID 19, komorbid penyakit kardiovaskular lebih banyak menunjukkan kasus yang berat. Bagaimana mekanisme komorbid ini memperburuk keluaran pasien masih tidak jelas, namun beberapa hipotesisnya antara lain usia lanjut, gangguan sistem imun, peningkatan kadar ACE2 atau mungkin ada hubungan antara COVID 19 dengan penyakit kardiovaskular. Tinjauan pustaka ini akan menjelaskan berbagai gangguan kardiovaskular yang mungkin terjadi pada infeksi COVID 19 secara lebih mendalam.
Validation of the Indonesian version of the Kansas city cardiomyopathy questionnaire in heart failure patients Syifa Mahmud Syukran Akbar; Habibie Arifianto; Heru Sulastomo; Niniek Purwaningtyas; Ahmad Yasa; Ari Natalia Probandari; Khusnun Alifah
Heart Science Journal Vol. 7 No. 2 (2026): The Evolving Landscape of Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.02.11

Abstract

BACKGROUND: Heart failure is one of the leading contributors to morbidity and mortality globally, and it has a significant impact on patients' quality of life. Accurate assessment of health-related quality of life (HRQoL) is essential in the management of heart failure patients; however, measurement tools in the local language remain limited. OBJECTIVES: The purpose of this study was to validate the Kansas City Cardiomyopathy Questionnaire (KCCQ) among Indonesian patients suffering from heart failure. METHODS: This study was an analytic observational cross-sectional study conducted from July to August 2023 at the cardiology outpatient clinics of UNS Hospital and Dr. Moewardi Hospital, Central Java. The adaptation process included forward-backward translation and preliminary testing. Validity was evaluated using Pearson correlation, and reliability was measured with Cronbach’s alpha. RESULTS: A total of 115 heart failure patients were included in this study. All 23 items in the Indonesian version of the KCCQ showed strong correlation values (r ≥ 0.154; p < 0.001) and excellent internal consistency (Cronbach’s alpha = 0.933). Domain analysis also demonstrated high reliability across all subscales. The KCCQ score had a strong negative correlation with the NYHA classification (r = -0.713; p < 0.001), but a weak and non-significant correlation with LVEF (r = 0.156; p = 0.097). CONCLUSION: The Indonesian version of the KCCQ is valid and reliable for assessing health-related quality of life in patients with heart failure.    
Co-Authors Ahmad Yasa Ari Natalia Probandari Dian Yaniarti Hasanah Heru Sulastomo Khusnun Alifah Lita Dwi Suryani Nana Maya Suryana Niniek Purwaningtyas Paskariatne Probodewi Siti Elkana Nauli Syifa Mahmud Syukran Akbar Vebiona Kartini Prima Putri Wahyu Aditya