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Bibliometric analysis of acute limb ischemia research: Global trends and key insights from 2000-2024 Abiseka Panji Baskoro; Enrico Ananda Budiono; Heru Sulastomo; An Aldia Asrial
Heart Science Journal Vol. 7 No. 1 (2026): Accelerating Clinical Breakthroughs: The Journey from Molecular Discovery to Pa
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.01.17

Abstract

Background: Acute Limb Ischemia (ALI) remains a critical vascular emergency, necessitating understanding to prevent devastating outcomes. Despite its clinical significance, a comprehensive understanding of global research trends, key contributors, and emerging themes in ALI remains underexplored. Objective: This study aims to perform a bibliometric analysis of ALI-related research, identifying trends, influential contributors, and areas for future exploration. Methods: Data were retrieved from the Scopus database using relevant keywords. Bibliometric metrics were analyzed using VOSviewer and Biblioshiny, focusing on publication trends, co-authorship networks, and keyword co-occurrence. Descriptive and visual analyses highlighted the leading journals, nations, and emerging research themes in ALI. Result: A total of 1,967 documents were identified, with a surge in publications from 2020 to 2021, likely driven by the COVID-19 pandemic's thrombotic implications. The United States led global research efforts with 28.5% of corresponding author articles and the highest citation impact. Annals of Vascular Surgery and Journal of Vascular Surgery emerged as the most relevant and influential journals, respectively. Keyword mapping identified "acute limb ischemia," "peripheral arterial disease," and "vascular surgery" as central themes, with emerging topics including novel anticoagulants, mechanical circulatory support, and congenital risk factors like persistent sciatic artery and congenital heart disease. Despite advancements, gaps persist in systematic reviews, meta-analyses, and evidence-based clinical evaluations. Conclusion: This study provides a comprehensive overview of ALI research, identifying trends and highlighting opportunities for further investigation. By addressing existing gaps and integrating emerging guidelines—such as the 2024 ESC and ACC recommendations—future research can advance clinical practice and improve outcomes for patients with ALI.
Validation of the Indonesian version of the Kansas city cardiomyopathy questionnaire in heart failure patients Syifa Mahmud Syukran Akbar; Habibie Arifianto; Heru Sulastomo; Niniek Purwaningtyas; Ahmad Yasa; Ari Natalia Probandari; Khusnun Alifah
Heart Science Journal Vol. 7 No. 2 (2026): The Evolving Landscape of Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2026.007.02.11

Abstract

BACKGROUND: Heart failure is one of the leading contributors to morbidity and mortality globally, and it has a significant impact on patients' quality of life. Accurate assessment of health-related quality of life (HRQoL) is essential in the management of heart failure patients; however, measurement tools in the local language remain limited. OBJECTIVES: The purpose of this study was to validate the Kansas City Cardiomyopathy Questionnaire (KCCQ) among Indonesian patients suffering from heart failure. METHODS: This study was an analytic observational cross-sectional study conducted from July to August 2023 at the cardiology outpatient clinics of UNS Hospital and Dr. Moewardi Hospital, Central Java. The adaptation process included forward-backward translation and preliminary testing. Validity was evaluated using Pearson correlation, and reliability was measured with Cronbach’s alpha. RESULTS: A total of 115 heart failure patients were included in this study. All 23 items in the Indonesian version of the KCCQ showed strong correlation values (r ≥ 0.154; p < 0.001) and excellent internal consistency (Cronbach’s alpha = 0.933). Domain analysis also demonstrated high reliability across all subscales. The KCCQ score had a strong negative correlation with the NYHA classification (r = -0.713; p < 0.001), but a weak and non-significant correlation with LVEF (r = 0.156; p = 0.097). CONCLUSION: The Indonesian version of the KCCQ is valid and reliable for assessing health-related quality of life in patients with heart failure.