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All Journal Jurnal Kesehatan Andalas Afiasi : Jurnal Kesehatan Masyarakat
Nicolas Layanto
Universitas Kristen Krida Wacana
Health Professions Immunology & microbiology Nursing Public Health

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A Gyssens Evaluation On Antibiotics Usage On Inpatients With Urinary Tract Infection In Hospital X, Central Jakarta, on January 2017 – June 2019: Gyssens Evaluation On Antibiotics Usage On Inpatients With Urinary Tract Infection In Hospital X, Central Jakarta, on January 2017 – June 2019 Henny Tannady Tan; Ade Dharmawan; Agus Cahyadi; Nicolas Layanto; Elisabeth Harahap
Afiasi : Jurnal Kesehatan Masyarakat Vol. 5 No. 3 (2020): Afiasi
Publisher : Universitas Wiralodra

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31943/afiasi.v5i3.113

Abstract

Urinary tract infections are infections from the bladder to the renal parenchyma, and can affect all ages. Empirical therapy can reduce morbidity, but due to the use of antibiotics that are not appropriate will have an impact on resistance that will cause increase morbidity, mortality, and health costs. In the Southeast Asian region, high use of antibiotics were found almost more than 80% in various provinces in Indonesia. This study aims to assess the appropriatness use of antibiotics in hospitalized patients with UTIs in the District Hospital X in the period January 2017 - June 2019 using gyssens criteria. This is retrospective study. Research data sourced from medical records. Data was collected and assessed with Gyssens flow, then processed using Microsoft Excel. The results found 15 cases (46.88%) with the appropriate use (category 0), 3 cases (9.37%) incorrect interval (category IIB), 1 case (3.33%) incorrect dosage (category IIA ), 10 cases (31.25%) too short given (category IIIB), 3 cases (9.37%) too long given (category IIIA). Empirical therapy inpatients with diagnosis urinary tract infections atvDistrict Hospital X, 46.8% of antibiotics were used appropriately.
Profil Bakteri Patogen dan Kepekaannya pada Pasien Ventilator Associated Pneumonia dengan Infeksi COVID- 19 di Rumah Sakit UKRIDA¬ Jeremy Christopher; Ade Dharmawan; Donna Mesina Pasaribu; Nicolas Layanto
Jurnal Kesehatan Andalas Vol 11, No 3 (2022): Online November 2022
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v11i3.1998

Abstract

The use of ventilators during the COVID-19 pandemic has increased the incidence of Ventilator-Associated Pneumonia (VAP). This is accompanied by a trend of antibiotic resistance resulting from irrational use. The emergence of multi-drug resistant (MDR) bacteria during the pandemic presents a challenge due to limited antibiotic options. Objective: To determined the pathogenic bacterial profile and antibiotic susceptibility in Ventilator Associated Pneumonia (VAP) patients with COVID-19 infection. Methods: This is a descriptive cross-sectional study with a retrospective approach using secondary data from the medical records of UKRIDA Hospital patients from January 2021 to August 2021. Results: Most of the study sample had characteristics of being male (71.9%), aged 25-64 years (78.1%), overweight (40.6%), and hypertension (40.6%) as the comorbid. Gram-negative bacteria is the pre-dominated bacteria in this study, with Acinetobacter baumannii, Klebsiella pneumoniae, and Stenotrophomonas maltophilia being the most isolated bacteria. Antibiotics such as colistin still showed good susceptibility to Acinetobacter baumannii and Klebsiella pneumoniae, with 75% and 90% sensitivities, respectively. Antibiotics such as linezolid, tigecycline, and gentamicin-synergy still showed (100%) sensitivity to all Gram-positive bacteria. Conclusion: The discovery of MDR bacteria in patients with VAP and the limited availability of susceptible antibiotics highlights the importance of conducting antibiotic resistance surveillance and infection control, especially in the era of COVID-19.Keywords:  antibiotic susceptibility, bacteria profile, COVID-19, VAP
Co-Authors Ade Dharmawan Agus Cahyadi Donna Mesina Pasaribu Elisabeth Harahap Henny Tannady Tan Jeremy Christopher