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All Journal Jurnal Kesehatan Andalas Jurnal Kedokteran Meditek
Donna Mesina Pasaribu
Universitas Kristen Krida Wacana
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Profil Bakteri Patogen dan Kepekaannya pada Pasien Ventilator Associated Pneumonia dengan Infeksi COVID- 19 di Rumah Sakit UKRIDA¬ Jeremy Christopher; Ade Dharmawan; Donna Mesina Pasaribu; Nicolas Layanto
Jurnal Kesehatan Andalas Vol 11, No 3 (2022): Online November 2022
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v11i3.1998

Abstract

The use of ventilators during the COVID-19 pandemic has increased the incidence of Ventilator-Associated Pneumonia (VAP). This is accompanied by a trend of antibiotic resistance resulting from irrational use. The emergence of multi-drug resistant (MDR) bacteria during the pandemic presents a challenge due to limited antibiotic options. Objective: To determined the pathogenic bacterial profile and antibiotic susceptibility in Ventilator Associated Pneumonia (VAP) patients with COVID-19 infection. Methods: This is a descriptive cross-sectional study with a retrospective approach using secondary data from the medical records of UKRIDA Hospital patients from January 2021 to August 2021. Results: Most of the study sample had characteristics of being male (71.9%), aged 25-64 years (78.1%), overweight (40.6%), and hypertension (40.6%) as the comorbid. Gram-negative bacteria is the pre-dominated bacteria in this study, with Acinetobacter baumannii, Klebsiella pneumoniae, and Stenotrophomonas maltophilia being the most isolated bacteria. Antibiotics such as colistin still showed good susceptibility to Acinetobacter baumannii and Klebsiella pneumoniae, with 75% and 90% sensitivities, respectively. Antibiotics such as linezolid, tigecycline, and gentamicin-synergy still showed (100%) sensitivity to all Gram-positive bacteria. Conclusion: The discovery of MDR bacteria in patients with VAP and the limited availability of susceptible antibiotics highlights the importance of conducting antibiotic resistance surveillance and infection control, especially in the era of COVID-19.Keywords:  antibiotic susceptibility, bacteria profile, COVID-19, VAP
Faktor-Faktor yang Berhubungan dengan Nilai Apgar Persalinan per Vaginam di RS UKI 2016 Diravita CFL Marsaulina; Ernawaty Tamba; Donna Mesina Pasaribu
Jurnal Kedokteran Meditek VOL. 23 NO. 62 APRIL-JUNI 2017
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v23i62.1555

Abstract

Ketuban pecah dini adalah pecahnya selaput ketuban sebelum adanya tanda persalinan. Ketuban pecah dini merupakan salah satu penyebab terjadinya asfiksia neonatorum dan infeksi yang meningkatkan mortalitas dan morbiditas perinatal. Nilai Apgar adalah cara untuk menilai kondisi bayi yang mencerminkan menurunnya fungsi-fungsi vital. Jenis penelitian yang digunakan adalah penelitian deskripsi dengan pendekatan cross-sectional dengan teknik pengambilan sampel. Besar sampel dalam penelitian ini adalah 100 sampel. Dari hasil penelitian, terdapat 53 bayi (77,9%) memiliki nilai Apgar kategori baik pada persalinan normal, dan 20 bayi (74,1%) memiliki nilai Apgar kategori asfiksia sedang pada persalinan ketuban pecah dini. Pada ibu yang memiliki riwayat hipertensi, terdapat 5 bayi (18,5%) memiliki nilai Apgar kategori asfiksia sedang. Uji statistik dengan Chi square menggunakan SPSS 16 for Windows didapatkan nilai X2 dengan nilai a = 0,05, dengan demikian p value yang dimiliki 0,031, maka H0 ditolak dan H1 diterima. Sehingga dapat diambil kesimpulan bahwa dalam penelitian ini terdapat hubungan antara penyakit infeksi saluran kemih ibu dengan nilai Apfar bayi.Kata kunci: persalinan, ketuban pecah dini, nilai Apgar
Co-Authors Ade Dharmawan Diravita CFL Marsaulina Ernawaty Tamba Jeremy Christopher Nicolas Layanto