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All Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Journal Orthopaedi and Traumatology Surabaya (JOINTS) SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Indonesia Journal of Physical Medicine and Rehabilitation Indonesia Journal Physical Medicine and Rehabilitation Physical Therapy Journal of Indonesia
Lydia Arfianti
Department Of Physical Medicine And Rehabilitation, Faculty Of Medicine, Universitas Airlangga, Dr. Soetomo Academic General Hospital, Surabaya, East Java, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health

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Journal : Indonesia Journal Physical Medicine and Rehabilitation

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Administration of Oral Curcumin to Resistance Exercise after Immobilization Does Not Affect Skeletal Muscle Fiber Diameter in Rattus Norvegicus I Putu Alit Pawana; Martha Kurnia Kusumawardani; Lydia Arfianti
Indonesian Journal of Physical Medicine & Rehabilitation Vol 11 No 01 (2022): Indonesian Journal Of Physical Medicine and Rehabilitation
Publisher : Indonesian Journal of Physical Medicine & Rehabilitation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36803/ijpmr.v11i01.328

Abstract

ABSTRACTIntroduction: The aim of this study was to explore the effect of adding oral curcumin to resistance exerciseafter immobilization on the diameter of skeletal muscle fiber in Rattus Norvegicus.Methods: This was a post-test only study design on animal model. Subjects of the study were male Rattusnorvegicus strain Wistar, age 10-12 weeks old, weigh between 150-300 g, were immobilized at soleusmuscle for 2 weeks, then randomly allocated to 3 groups: (i) control group, (ii) resistance exercise, (iii)oral curcumin + resistance exercise. After 4 weeks of intervention, the diameter of the muscle fibers wasmeasured.Result: The results of this study showed a significant difference on the diameter of skeletal muscle fiberbetween control group and resistance exercise, as well as control group and resistance exercise + oralcurcumin (p<0.05). There was no significant difference between resistance exercise only and resistanceexercise + oral curcumin (p>0.05).Conclusion: Administration of oral curcumin to resistance exercise after immobilization does not affectskeletal muscle fiber diameter in Rattus Norvegicus.Keywords : curcumin, good health and well-being, immobilization, resist ance exercise, skeletal muscle.
Co-Authors Al Hayyan, Abdul Jabbar Atika , Atika Desnantyo, Andre Triadi Gutama Arya Pringga Handajani , Noor Idha Imam Subadi, Imam Martha Kurnia Kusumawardani Meisy Andriana, Meisy Pawana, I Putu Alit Prawitri , Yudith Dian Putri, Nelsya Safira Aulia Ratna Darjanti Haryadi, Ratna Darjanti Rizqi, Fahmi Aulia Semedi, Bambang Pujo Soenarnatalina Melaniani Utama Hutapea, Johannes Diandra Indra Wardhani, Indrayuni Lukitra Wico Hartantri