Article Per Year (5 Year)
p-Index From 2020 - 2025
2.757
P-Index
This Author published in this journals
All Journal BALI MEDICAL JOURNAL (BMJ) Jurnal VOK@SINDO Folia Medica Indonesiana Jurnal NERS MNJ (Malang Neurology Journal) Health Notions Journal Orthopaedi and Traumatology Surabaya (JOINTS) SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL Majalah Biomorfologi (Biomorphology Journal) Indian Journal of Forensic Medicine & Toxicology Journal of Social Research Journal of Pain, Vertigo and Headache
Imam Subadi
Department Of Physical And Rehabilitative Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya/ Dr. Soetomo General Academic Hospital, Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 25 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 25 Documents
Search

 1   2   3 
HUBUNGAN EKSPRESI HSP 70 DAN EKSPRESI RESEPTOR OPIOID MU PADA PENURUNAN NYERI TERAPI BEKAM BASAH Subadi, Imam; Laswati, Hening; JM, Harjanto
Jurnal NERS Vol 11, No 1 (2016): Jurnal Ners
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (456.452 KB) | DOI: 10.20473/%oj.Ners111%y34-39

Abstract

Latar belakang. Terapi bekam basah banyak digunakan untuk mengurangi nyeri,  namun mekanisme penurunan nyeri terapi bekam basah belum jelas. Peregangan dan tusukan pada terapi bekam basah menimbulkan stres pada sel. Sel yang mengalami stres mengekspresikan HSP 70 dan reseptor opioid mu.Tujuan penelitian. Penelitian ini bertujuan membuktikan korelasi  peningkatan ekspresi HSP 70 dan peningkatan reseptor opioid mu pasca terapi bekam basah.Bahan dan Metode. Jenis penelitian ini adalah penelitian eksperimental dengan rancangan randomized control group post test only design. Dua puluh empat tikus jenis Wistar (Rattus norvegicus)  secara random dibagi menjadi tiga kelompok yang masing-masing terdiri dari 8 ekor tikus yaitu kelompok kontrol negatif (tikus normal), kelompok induksi nyeri dengan Complete Freund’s Adjuvant (CFA) saja (kontrol positif) dan kelompok  yang diberi induksi nyeri dan terapi bekam basah (10 tusukan dan tekanan negatif: - 200 mmHg, 5 menit).  Sampel diambil dari kulit dan dilakukan pemeriksaan imunohistokimia dengan antibodi monoklonal anti reseptor opioid mu. Waktu reaksi ambang nyeri diukur memakai hot-plate. Data dianalisa dengan Anova oneway dan Pearson Correlation dengan menggunakan SPSS versi 17.Hasil. Penelitian ini menunjukkan bahwa terdapat peningkatan ekspresi HSP 70 (20,25 ± 3,53; p< 0.05) dibandingkan kelompok kontrol positif (10,50 ± 2,44; p< 0,05) dan peningkatan ekspresi reseptor opioid mu  (21,00 ± 6,34; p< 0.05) dibandingkan kelompok kontrol positif ( 4,25 ± 3,58; p< 0.05). Terdapat peningkatan waktu reaksi ambang nyeri (22,81 ± 6,34; p< 0,05) dibandingkan kontrol positif (11,78 ± 3,56). Terdapat korelasi antara peningkatan ekspresi HSP 70 dan peningkatan reseptor opioid mu  (β= 0.893; p= 0.000) dan ada korelasi antara peningkatan reseptor opioid mu dengan waktu reaksi ambang nyeri (β= 0.713; p= 0.002).Kesimpulan. Terjadi peningkatan ekspresi HSP 70 dan reseptor opioid mu pada terapi bekam basah dan terdapat korelasi antara peningkatan ekspresi HSP 70 terhadap ekspresi reseptor opioid mu.Kata kunci : HSP 70, reseptor opioid mu dan bekam basah 
COMPARISON OF ACUTE ISCHEMIC STROKE FUNCTIONAL OUTCOME IN SMOKERS AND NONSMOKERS MEASURED BY CANADIAN NEUROLOGICAL SCALE (CNS) AND NIHSS Putri, Nila Novia; Islam, Mohamad Saiful; Subadi, Imam
Malang Neurology Journal Vol 4, No 2 (2018): July
Publisher : Malang Neurology Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (435.561 KB) | DOI: 10.21776/ub.mnj.2018.004.02.4

Abstract

Background. Stroke is the world’s second leading cause of death and main cause of disability. Smoking is a well-known risk factor of stroke. However, the correlation between smoking and stroke outcome is still remains a controversy.Objective. To analyze the differences of functional outcome between smokers and non-smokers in acute ischemic stroke patients.Methods. The design used in this study is retrospective cross-sectional. The functional outcomes of acute ischemic stroke were measured by Canadian Neurologic Scale (CNS) and NIHSS over a period of seven days after the onset of stroke. Differences of CNS and NIHSS were analyzed using Mann-Whitney U test.Results. Median of CNS in smokers and non-smokers were 9.0 and 11.0, respectively. Median of NIHSS in smokers and non-smokers were 4.0 and 2.0, respectively. There were no significant differences in the analysis of CNS score between smokers and non-smokers and NIHSS score analysis between smokers and non-smokers.Conclusion. Smoking is not correlated with the functional outcome in acute ischemic stroke patients measured by CNS and NIHSS.
SPILANTHES ACMELLA AND PHYSICAL EXERCISE INCREASED TESTOSTERONE LEVELS AND OSTEOBLAST CELLS IN GLUCOCORTICOID-INDUCED OSTEOPOROSIS MALE MICE Laswati, Hening; Subadi, Imam; Widyowati, Retno; Agil, Mangestuti; Pangkahila, Jahya Alex
BALI MEDICAL JOURNAL Vol 4 No 2 (2015)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (469.999 KB)

Abstract

Background: Glucocorticoid-induced osteoporosis is leading cause of secondary osteoporosis by decreasing formation activity and increasing resorption activity. Spilanthes acmella, is one of Indonesia medicinal plants that contain of polyphenol and flavonoids. Previously in vitro study showed that buthanol and water fraction from this plant have increased alkaline phosphatase that known as marker of bone formation. The objective of this study to analyze the effect of Spilanthes acmella and physical exercise in increasing testosterone and osteoblast cells of femoral’s trabecular glucocorticoid-induced osteoporosis male mice. Method: This study using a posttest control group design, 36 male healthy mice (5 months old) were randomizely devided into 6 groups, there are : 1.Healthy control group (without induction dexamethaxone), 2.Osteoporosis groups (induction with dexamethaxone without treatment), 3.Positive control receive suspension alendronat, 4.70% Ethanol extract of Spilanthes acmella group, 5.Combination group of 70% extract ethanol of Spilanthes acmella and exercise, and 6.Exercise group (walking using mice treadmill 10m/minute, 5-12 minutes 3 times a week). All of the intervention were given for 4 weeks. The serum levels of testosterone were determined using immunoserology (ELISA) and osteoblast cells were determined histomorphometry by light microscopy. All statistical test were carried out using SPSS 23 and statistical significance was set at p
Tomato (Lycopersicum commune) Juice and Physical Exercise Increase Number of Neurons and ER? expression in Post-Ovariectomy Rats Brain Laswati, Hening; Subadi, Imam; Andriana, Meisy; Kurniawati, Patricia Maria; Pangkahila, Jahya Alex
BALI MEDICAL JOURNAL Vol 5 No 3 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (597.331 KB)

Abstract

Background: Estrogen deficiency condition can degrade the quality of life, decline in cognitive function will be more severe trough age. Phytoestrogen compounds can be found in pegaga leaf extract, tomatoes, and papaya is an easy and inexpensive way to increase estrogen levels in post menopause women through extra gonadal estrogen induction. Therefore, the aims of this study were to examine the effect of tomato juice, physical exercise, and combination of these treatments on promoting neurons and ER? expression in somatosensory cortex that contribute to cognitive function of post-ovariectomy rats. Method: Twenty-eight female healthy Wistar rats (Rattus novergicus), 8-10 weeks old, from Laboratory of Biochemistry, Faculty of Medicine Airlangga University include in this experiment. The animals were housed in the animal-care facility with ad libitum food and water. The temperatur was maintained at 18°C-24°C. The treatments were done 2 weeks after ovariectomy. Tomato were made in Laboratory of Pharmacognocy and Phytochemistry, Faculty of Pharmacy, Airlangga University, from inner part of the tomato fruits (mucous like substance) with freeze dry method (-40°C). Results: The weight of white rat Rattus norvegicus post ovariectomy in this study was between 133-170 gram with a mean weight 154.32 ± 9.72 gram. Hematoxylin/eosin staining showed neuronal deficit in the control rats brain. In figure 1, the tomato group showed the largest of neurons number (145.43 ± 17.728), followed the combination group (140.57 ± 22.449), the exercise group (136.86 ± 23.104) and the smallest number in the control group (96.43± 28.965). Four weeks after treatments the number of neurons increased significant in the tomato group (p=0.001), exercise group (p=0.004) and combination group (p=0.002) from the control group. This study showed no significant different between tomato and exercise group (p=0.500), tomato and combination group (p=0.701) and between exercise and combination group (p=0.769). Conclusions: In conclusion, our data demonstrated that post ovariectomy rats showed deficit numbers of neurons and decreased ER? in the somatosensory cortex. Treatment with physical exercise, tomato juice, and combination of these treatments increased the number of neurons and ER? expression in the somatosensory cortex.
Immediate Effect of Vibrating Foam Roller on the EMG Amplitude of Muscle Hamstring of Healthy Subject with Hamstring Tightness Ahmad Arif Ridha; Nuniek Nugraheni; Imam Subadi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15594

Abstract

Association between Physical Characteristics and Locomotive Syndrome in Elderly in Surabaya, Indonesia Benni Azhari; Imam Subadi; Patricia Maria Kurniawati
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15709

Abstract

The locomotive syndrome (LS) is a condition of reduced mobility due to impairment of locomotive organ. The LS was screened by Lococheck in elderly population. Prior research has been shown that physical characteristic such as age, gender, body weight, body height and body mass index has correlation with mobility limitation in elderly. We aimed to asses if the physical characteristic in elderly is able to use as a screening tool for locomotive syndrome in Indonesia. To investigate the association between physical characteristic and locomotive syndrome in elderly. This study was an observational cross-sectional study. A total 63 participants (37 females and 27 males) age 60-78 years participated in this study. This study was conducted by filling the Lococheck Indonesian version and measuring physical characteristic (Age, gender, body weight, body height and body mass index). The correlation between the Lococheck Indonesian version with physical characteristic was analyzed using Kendall’s tau correlation test. Forty participant answer “yes” at least one item of the lococheck Indonesian version questionnaire. The lococheck result showed an insignificant correlation with age r<0.3 (0.01), p>0.05 (0.926), gender r<0.3 (0.061), p>0.05 (0.563), Body weight r<0.3 (0.061), p>0.05 (0.562), body height r<0.3 (-0.104), p>0.05 (0.328) and body mass index r<0.3 (0.122), p>0.05 (0.245). To sum up, these findings confirmed that no correlation between physical characteristic and locomotive syndrome in elderly
Effect of Neuromuscular Electrical Stimulation Addition in Exercise with Expiratory Muscle Trainer on FEV1 And FVC in Untrained Healthy Subjects Langgeng Gunariadi; Imam Subadi; Dewi Poerwandari
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.15841

Abstract

Coughing is a mechanism for expelling foreign particles or excess mucus in the airway by increasinghigh expiratory pressure. When coughing, the respiratory muscles that control cough production are theinspiratory and expiratory muscles. Weakness of the expiratory muscle can affect to the ability to generatesufficient pressure to cough. In generally, a decrease in respiratory muscle’s strength can occur in patientswho have experience of prolonged immobilization, elderly people who suffer from sarcopenia, to strokepatients. The untrained healthy persons were not realizing the effects of their lifestyle which can reduce therectus abdominis muscle as an additional expiratory muscle. If it occurred in long time, it will reduce thelung function capacity of force expiratory volume (FEV1) and force vital capacity (FVC). The subjects ofthis study were 16 untrained healthy males with aged 18-40 years. Furthermore, they divided into 2 groups,the intervention group with Expiratory Muscle Trainer (EMT) training plus of Neuromuscular ElectricalStimulation (NMES) on the rectus abdominis muscle and the control group with exercise with ExpiratoryMuscle Trainer only. The outcome was measured for FEV1 and FVC by spirometry. The results of this studywere indicating an increase in FEV1 and FVC in each group however. The intervention group was increaseof FEV1 0.22+0.22 (p value=0.18) and the control group was 0.01+0.39 (p value=0.92). The interventiongroup was increase of FVC 0.50+0.48 (p value=0.02) and the control group was 0.32+0.51 (p value=0.12).The FEV1 results between the two groups were not significant difference (p value=0.21) and as well as FVCresults after 4 weeks of training. In summary, this study concluded that EMT training with NMES increasedFVC even though the difference between the two was not significant.
Profile of Colles Fracture Patients at Dr. Soetomo General Hospital Andre Triade Desnantyo; Imam Subadi; Fiequria Asri Ersyana
Health Notions Vol 5, No 8 (2021): August
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn50804

Abstract

Colles fracture is the most common wrist fracture, with a incidence of 24% among the working population, where fracture through the radius cause the distal part to be displaced radially dan dorsally. These fractures of the distal radius are often caused by a fall on the outstretched hand with the wrist in dorsoflexion, causing tension on the volar aspect of the wrist, causing the fracture to extend toward the back of the hand. The incidence of Colles fracture is most common in adults over the age of 50 years and more common in women then men because of the onset of postmenopausal osteoposrosis where falls with outstretched arms are the most common cause. The purpose of this study was to determine the profile of patients with Colles fracture at Dr Soetomo Hospital Surabaya for the period January 2019 – 2020.  This research is a descriptive study with a cross-sectional approach that takes secondary data. In this study, there were 121 case samples after the inclusion and exclusion criteria were carried out. The conclusion of this study, based on the Frykman classification, Colles fracture moat often occur in Frykman 1. Based on the age, Colles fracture most often occur in late elderly patients, namely at the age of 56-65 years. According to mode of injury, Colles fracture are the most common in patients who fall. Based on the treatment given to the patient, most Colles fracture patients were treated with a combination of operative and conservative.Keywords: colles fracture; profile
Expression of Β-Endorphin In Relieving Inflammation Pain after Dry Cupping Therapy Imam Subadi
Jurnal VOK@SINDO Vol 2, No 2 (2014)
Publisher : Program Pendidikan Vokasi Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (371.138 KB)

Abstract

Pain is a chief complaint most frequently seen in daily practice. Dry cupping therapy has been used for pain management but the mechanism of action is unclear. Beta endorphin is an endogenous morphin that can relief pain.The objective of this study is to show the relationship betweenβ-endorphin expression and pain relief in dry cupping.This experimental study employed randomized control group post test design. Twenty four Wistar rats (Rattus norvegicus) were assigned to three groups of 8 subjects, which were normal rats (control negative), group undergoing Complete Freund’s Adjuvant (CFA) only (control positive group) and group undergoing CFA and dry cupping (negative pressure: - 200 mmHg, 5 minutes). Samples were retrieved from skin and performed immunohistochemical of monoclonal anti β-endorphin. Pain threshold reaction time was measured by hot-plate. Data were then statistically analysed by Independent-Sample t Test, Linear Regresion analysis using SPSS version 17.This study found out that expression of β-endorphin, p= 0.000 and pain threshold reaction time on dry cupping, p= 0.001 had increased compared with the control group. There was relation between increased β-endorphin with pain threshold reaction time in dry cupping (β= 0.542; p= 0.030). In other words, dry cupping can decrease pain caused by the expression of β-endorphin
Validity and Reliability of WHO Disability Assessment Schedule 2.0 (WHODAS 2.0) Type 12 Questions Indonesian Version on Back Pain Kusumawardhany Airlangga Rijanti; Imam Subadi; Patricia Maria Kurniawati
Folia Medica Indonesiana Vol. 57 No. 3 (2021): September
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.131 KB) | DOI: 10.20473/fmi.v57i3.13580

Abstract

The study was to prove the validity and reliability of the WHODAS 2.0 Indonesian version questionnaire in patients with back pain. This study was an observational cross-sectional study conducted in 2018. The study included the filling of WHODAS 2.0 Indonesian version, Indonesian version of Oswestry Disability Index (ODI) questionnaire, Wong-Baker Scale, conducted at Department of Rehabilitative Medicine, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, against 82 respondents with back pain. Each respondent was given informed consent. The validity of the WHODAS 2.0 Indonesian version questionnaire was measured using Pearson's test on the correlation of WHODAS 2.0 Indonesian version questionnaire and Oswestry Disability Index questionnaire with r >0.3 (0.862). WHODAS 2.0 Indonesian version questionnaire and Wong-Baker Scale had r >0.3 (0.449–0.785). The reliability of the WHODAS 2.0 Indonesian version questionnaire was measured using Pearson's correlation test with r >0.3 (0.764–0.866). WHODAS 2.0 Indonesian version's internal reliability was tested using Cronbach-Alfa Test with alpha >0.6 (0.634–, 853). In conclusion, the WHODAS 2.0 - Indonesian version is a valid and reliable questionnaire for patients with back pain. 
Co-Authors Afifur Rafi Hilmi Aziz Ahmad Arif Ridha Ana Mursyida Andre Triade Desnantyo Andriana, RA Meisy Andriati Andriati Andriati Andriati Benni Azhari Damayanti Tinduh Dewi Septiani M K Sintia Diah Indriani Fauza Alfin Fidiana Fiequria Asri Ersyana Hanik Hidayati HARJANTO HARJANTO Harjanto JM Harjanto JM Hening Laswati Putra Islam, Mohamad Saiful J. A. Pangkahila Jeremy Nicolas Sibarani Kusumawardhany Airlangga Rijanti Langgeng Gunariadi Lydia Arfianti Mangestuti Agil Martino, Nieko Caesar Agung Masduchi, Reni Hendrarati Mulyana, Darian Nugraheni S. Nuniek Nuniek Nugraheni Nur Sulastri Nur Sulastri Patricia Maria Kurniawati Paulus Sugianto, Paulus Pawana, I Putu Alit Poerwandari, Dewi Putri, Nila Novia Raden Argarini Rejeki, Purwo Sri Retno Widyowati Rwahita Satyawati Dharmanta Semedi, Bambang Pujo Sirly Nabireta Maharani Ganing, Sirly Nabireta Soenarnatalina Melaniani Soenarnatalina Melaniani Sony Wibisono Subagyo Subagyo Tedy Apriawan Turchan, Agus Utama Hutapea, Johannes Diandra Indra Vanydia Aisyah Wardhani, Indrayuni Lukitra Wigati, Kristanti Wanito Yuanita, Ida Yuli Indah Kurnia Yuliasih Yuliasih