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Pengaruh Variasi Konsentrasi Polivinil Pirolidon K-30 sebagai Pengikat dalam Pembuatan Oral Fast Dsissolving Tablet Domperidon Base Deny budi legowo; Riski Ramadhan; Erna Fitriany; Indah Tri Lestari
AFAMEDIS Vol. 2 No. 1 (2021): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.424 KB)

Abstract

Domperidone base as anti-nausea or vomiting drug mostly available in conventional tablets forms has weakness in swallowing tablets and requires drinking water. Oral fast dissolving tablets are a solution to this problem. Oral fast dissolving tablets with variations in the concentration of PVP K-30 to determine effect of the tablet physical quality test and good physical quality results. The wet granulation method was used to improve the flow properties by mixing the binder mucilago with the inner phase. Test of physical quality of tablets, weight uniformity, size uniformity, hardness, friability, disintegration time, and unifomity of content. The results showed a significant difference in friability and disitegration time. The conclusion based on the results of the study showed that the variation in the concentration of PVP K-30 on the difference in the physical quality test of tablets and the 2% concentration of PVP K-30 gave good results
Non-Medical Students Knowledge at Universitas Pesantren Tinggi Darul Ulum Jombang among the Use of Antacids From May to June 2023: Gambaran Pengetahuan Mahasiswa Non Kesehatan di Universitas Pesantren Tinggi Darul Ulum Jombang terhadap Penggunaan Obat Antasida Periode Mei-Juni 2023 Andri Priyoherianto; Erna Fitriany; Deny Budi Legowo; Sih Wahyuni Raharjeng
Journal Pharmasci (Journal of Pharmacy and Science) Vol. 9 No. 1 (2024): Journal Pharmasci (Journal of Pharmacy and Science)
Publisher : Akademi Farmasi Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53342/pharmasci.v9i1.353

Abstract

ABSTRACT Antacids are stomach acid neutralizing drugs that are efficacious for relieving stomach ulcer pain. It is a gastric pain medicine or gastritis which is quite easy to get by every individual. This study aims to describe the knowledge of the use of antacid drugs in non-health students. Conducted at the Faculty of Teacher Training and Education, Mathematics Study Program, Pesantren Tinggi Darul Ulum University, Jombang. This research is a quantitative research with descriptive method. The data was obtained using an instrument in the form of a questionnaire sheet with a sample of 59 students using a saturated sampling technique to determine the sample. The data were analyzed by scoring the answers on the questionnaire. The results of this study showed that 37 (62%) students with a history of gastritis and the remaining 22 (38%) had no history of gastritis. As many 3 respondents in the category of good knowledge, 16 respondents in the category of sufficient knowledge, 40 respondents in the category of less knowledge. The final result obtained an average of 53%, so that in this study the level of knowledge of respondents about the use of good and correct antacid drugs is still lacking. Keywords: Antacids, Grastritis, Student Knowledge