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Muharam Priatna
STIKes Bakti Tunas Husada Tasikmalaya
Chemistry Medicine & Pharmacology Public Health

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SINTESIS DAN IDENTIFIKASI STRUKTUR SENYAWA 3-(3,5-DINITROBENZOIL)-1-FENILTIOUREA SEBAGAI KANDIDAT ANTIKANKER Susanti Susanti; Ruswanto Ruswanto; Muharam Priatna
Pharmacoscript Vol. 1 No. 2 (2018): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v1i2.102

Abstract

Thiourea derivatives are known to be potential anticancer agents. 3-(3,5-dinitrobenzoyl)-1-phenylthiourea as a thiourea derivatives has been synthesized through acylation between 3,5-dinitrobenzoyl chloride and 1-phenylthiourea in tetrahydrofuran with triethylamine ascatalyst through reflux process with stirring for 6 hours. The percentage of yield was13,86%. The purity of the product was shown by the single spot on the TLC and narrowrange of melting point. The structure identification results with UV spectrophotometry, IRspectroscopy and 1HNMR spectroscopy showed that the structure of the product wasappropriate to the prediction.
Co-Authors Ruswanto, Ruswanto Susanti Susanti