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All Journal Jurnal Abdidas JURMA : Jurnal Program Mahasiswa Kreatif Aptekmas : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmacy and Natural Product
Nurul Jannah
Farmasi, Fakultas Sains Dan Teknologi, Universitas PGRI Yogyakarta
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PENGARUH INTERVENSI TERHADAP PENGETAHUAN WARGA TENTANG DAGUSIBU DI PADUKUHAN KARANG TENGAH, SLEMAN Margala Juang Bertorio; Rahmat A. Hi Wahid A Hi Wahid; Nurul Jannah; Anis Febri Nilansari; Hanifah Karimatulhajj
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 3 No 3 (2020): APTEKMAS Volume 3 Nomor 3 September 2020
Publisher : Politeknik Negeri Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.14 KB) | DOI: 10.36257/apts.v3i3.2126

Abstract

The ease of access to information about drugs through online media is a challenge in disseminating correct drug information. One way to manage drugs that is good and right is to implement a DAGUSIBU counselling program (DApatkan, GUnakan, SImpan, BUang). The program initiated by the Indonesian Pharmacists Association is an effort to improve health for the community, which is carried out through health care activities by pharmacists. Community empowerment in Padukuhan Karang Tengah, Nogotirto, Gamping, Sleman, Yogyakarta supports increased understanding and knowledge of the community related to DAGUSIBU. This empowerment activity was used lecture and discussion methods. Before the activity, residents were given a pretest to find out the level of knowledge. Than, posttest was given to all respondent to find out the change knowledge. The results of the pretest show that 66.67% of the correspondent is in a very knowledgeable group. After the intervention, as much as 89.22% of the people were in the group of very know. Interventions in the community increased community knowledge about DAGUSIBU by 22.59%. Other research is needed with a longer duration of the intervention and the distance between pretest and posttest for one month.
Pendampingan Remaja di Kota Yogyakarta dalam Upaya Pencegahan Konsumsi Tinggi Sugar Sweetened Beverages, Obesitas, dan Penyakit Berisiko Astri Praba Shinta; Nurul Jannah; Ryan Rohmansyah
Jurnal Abdidas Vol. 2 No. 6 (2021): December Pages 1257-1486
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/abdidas.v2i6.467

Abstract

Dari tahun ke tahun konsumsi Sugar-Sweetened Beverages atau minuman dengan tambahan gula (SSB) di Indonesia terus mengalami peningkatan. Hal ini dapat memicu peningkatan berat badan dan berisiko terjadinya obesitas. Remaja usia sekolah mulai mengalami peningkatan selera makan namun tidak diikuti dengan aktivitas fisik yang cukup sehingga dapat menimbulkan risiko terjadinya obesitas. Status gizi pada remaja akan menyebabkan perubahan status gizi di masa dewasa. Obesitas menjadi salah satu faktor pemicu penyakit-penyakit berisiko. Kegiatan pendampingan berupa pendidikan kesehatan dilaksanakan dengan menggunakan metode ceramah dan diskusi. Pada proses pendidikan kesehatan, para siswa diberikan kesempatan untuk berdiskusi tentang risiko konsumsi tinggi SSB dan obesitas. Materi pendidikan kesehatan yang diberikan adalah mencakup bidang gizi dan farmasi. Pendampingan remaja dengan pendidikan kesehatan ini dapat menjadi salah satu upaya dalam pencegahan obesitas pada remaja. Selain itu, pendidikan kesehatan yang berisi tentang pemilihan makanan dan minuman yang sesuai dengan gizi seimbang, aktivitas fisik untuk remaja, serta risiko konsumsi tinggi SSB dan obesitas dapat meningkatkan pengetahuan, menurunkan tingkat konsumsi SSB, serta meningkatkan kesadaran akan pentingnya gizi seimbang dalam upaya pencegahan terjadinya obesitas.
Studi In Silico Analog Heksagamavunon-6 Sebagai Anti-Helicobacter Pylori Nurul Jannah
Indonesian Journal of Pharmacy and Natural Product Vol. 3 No. 2 (2020)
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.372 KB) | DOI: 10.35473/ijpnp.v3i2.554

Abstract

ABSTRAKInfeksi Helicobacter pylori (H. pylori) menyebabkan timbulnya berbagai masalah pada saluran cerna, seperti gastritis kronik, peptic ulcer, gastric mucosa-associated lymphoid tissue (MALT) hingga menimbulkan kanker. Resisten terhadap antibiotik terus mengalami peningkatan menuntut segera ditemukannya pengobatan baru yang efektif. Penelitian ini bertujuan untuk mengevaluasi potensi senyawa Heksagamavunon-6 (HGV-6) dan analognya (D144, D154, dan D156) sebagai anti-H.pylori. Program AutoDock Vina digunakan pada proses penambatan molekul. Ligan uji, HGV-6 dan analognya, ditambatkan pada enzim shikimat kinase (PDB ID: 3N2E) dan urease (PDB ID: 1E9Y) sebagai target kerja dalam menghambat bakteri H.pylori. Parameter yang diamati berupa energi ikatan (kkal/mol) antara ligan uji dan protein dibandingkan dengan energi ikatan antara ligan asli dengan protein. Hasil penambatan pada enzim shikimat kinase menunjukkan bahwa energi ikatan senyawa HGV-6 (-9,2) dan D156 (-8,8) lebih rendah dibandingkan dengan energi ikatan ligan asli (-8,7), sedangkan D144 (-8,0 ) dan D154 (-8,4 ) memiliki energi ikatan yang lebih tinggi. Nilai energi ikatan antara enzim urease dengan HGV-6 (-7.7), D156 (-7,7), D154 (-6,7) dan D144 (-6,7) lebih rendah dibandingkan dengan energi ikatan enzim urease dengan ligan asli (-3,5). HGV-6 dan D156 memiliki potensi sebagai anti- H.pylori lebih tinggi dibandingkan analog lainnya. Penelitian lebih lanjut secara in vitro perlu dilakukan untuk mengevaluasi potensi HGV6 dan analognya sebagai  anti- H.Pylori.Kata kunci : Shikimat kinase, Urease, HGV-6, H. pylori, docking molekul, AutoDock VinaHelicobacter pylori (H. pylori) infections cause various gastrointestinal problems, such as chronic gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue (MALT) and cancer. Antibiotic resistance continues to increase, demanding that new effective treatments found immediately. This study aim was to evaluate the potential of the hexagamavunon-6 (HGV-6) compound and its analogues (D144, D154, and D156) as anti-H. pylori. AutoDock Vina program was used for molecular docking. The ligand, HGV-6 and its analogues, was docked to the enzyme shikimate kinase (PDB ID: 3N2E) and urease (PDB ID: 1E9Y) as a target of action to inhibit H. pylori bacteria. The parameter observed was the binding energy (kcal/mol) between the ligand and protein compared with the binding energy between the native ligand with protein. The results of docking protocol to the shikimate kinase enzyme showed that the binding energy of HGV-6 (-9.2) and D156 (-8.8) are lower than native ligand binding energy (-8.7), whereas D144 (-8.0) ) and D154 (-8.4) have higher binding energy. The binding energy values between the urease enzyme and HGV-6 (-7.7), D156 (-7.7), D154 (-6.7) and D144 (-6.7) are lower than the binding energy of the urease enzyme with the native ligand ( -3.5). HGV-6 and D156 have higher anti-H.pylori potential than others. Further in vitro research needs to be carried out to evaluate the potential of HGV6 and its analogues as anti-H. pylori.Keywords: Shikimate kinase, Urease, HGV-6, H. pylori, molecular docking, AutoDock Vina
Counseling on Rational Drug Use (DAGUSIBU) in Sembungan Village, Bangunjiwo, Kasihan, Bantul, D.I.Yogyakarta Rahmat A Hi Wahid; Nurul Jannah; Fathah Dian Sari
Jurma : Jurnal Program Mahasiswa Kreatif Vol 7 No 2 (2023): DESEMBER 2023
Publisher : LPPM UIKA Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/jurma.v7i2.1827

Abstract

Obtaining, Using, Storing and Disposal of drugs (DAGUSIBU) is part of the Drug Awareness Family Movement (GKSO) initiated by the Indonesian Pharmacist Association (IAI) in achieving understanding and awareness of the rational use of drugs. Community empowerment in Sembungan, Bangunjiwo, Kasihan, Bantul, D.I Yogyakarta hamlets aims to: (1) increase public understanding regarding the classification of drugs on the market and their differences (hard drugs, limited over-the-counter drugs, over-the-counter drugs, mandatory drug pharmacies), (2) increase public understanding regarding various types of drug preparations and how to use each to obtain the expected therapeutic effect, (3) increase public understanding regarding procedures for storing and disposing of unused drugs. This service activity uses lecture methods and interactive discussions. Before the speaker delivers the material, the respondent is given a pretest to determine the level of knowledge. While the posttest is given at the end of the delivery of the material to find out changes in knowledge. The pretest results show 64.8% (Enough). After the intervention, there was a change in the level of knowledge to 74.4% (Good). Based on these results it can be concluded that PKK cadres in Sembungan, Bangunjiwo, Kasihan, Bantul, D.I Yogyakarta have good knowledge about DAGUSIBU.
Co-Authors Anis Febri Nilansari Astri Praba Shinta Fathah Dian Sari Hanifah Karimatulhajj Margala Juang Bertorio Rahmat A Hi Wahid Rahmat A Hi Wahid Ryan Rohmansyah Wahid, Rahmat A Hi