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Yovita Ananta
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Health Professions Medicine & Pharmacology

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Inflammatory bowel disease in Indonesian children Badriul Hegar; Yovita Ananta; Diah Rini
Paediatrica Indonesiana Vol 47 No 6 (2007): November 2007
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (437.307 KB) | DOI: 10.14238/pi47.6.2007.307-12

Abstract

Inflammatory bowel disease (IBD) is a term usedto describe two disorders associated withgastrointestinal inflammation: Crohn’s disease(CD) and ulcerative colitis (UC). The incidenceof IBD is higher in developed countries, while there isunpublished data of pediatric IBD in Indonesia.Clinical manifestations of IBD vary, consist ofgastrointestinal (such as diarrhea and abdominal pain)and extraintestinal manifestations. Definite diagnosisof IBD is based on endoscopy and histopathology. Themanagement includes pharmacotherapy, nutrition,surgery, and psychotherapy. This disorder has a highrecurrence rate, where CD’s recurrence rate is higherthan UC.1,2
Comparison of peak expiratory flow measurement by Mini-Wright peak flow meter and electronic spirometer in healthy elementary school children Mardjanis Said; Sudigdo Sastroasmoro; Bambang Supriyatno; Yovita Ananta
Paediatrica Indonesiana Vol 44 No 6 (2004): November 2004
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.656 KB) | DOI: 10.14238/pi44.6.2004.248-52

Abstract

Objective This study aims to compare peak expiratory flow mea-surement by peak flow meter and electronic spirometer in healthyelementary school children.Methods This was a cross-sectional study performed in an el-ementary school near Cipto Mangunkusumo hospital (SDNPegangsaan 01). The study group consisted of healthy childrenaged 6-12 year old. Data regarding identity and history of illnesswas taken in each subject. Routine physical examination was per-formed and recorded. Each subject performed lung function testsby means of electronic spirometer AS-7 as well as by Mini-Wrightpeak flow meter. The subject should perform a minimum of threemaneuvers for each method where only the best result was re-corded. Method comparison test to assess agreement betweentwo methods was employed in this study.Results There were 10 males and 15 females enrolled in this study.None of the subjects currently have any respiratory symptoms andsigns. This study found that the mean peak expiratory flow (PEF) byspirometer was 226.8±73.13 L/min while by peak flow meter was223.0±45.05. Mean difference between spirometer and peak flowmeter measurements is 6.2 with standard deviation of 60.82. Thesevalues resulted in limits of agreement of -115.44 to +127.84 L/min.Conclusions This study finds disagreement between electronicspirometer and Mini-Wright peak flow meter in measuring peakexpiratory flow, therefore these two devices cannot be usedinterchangeably. Mini-Wright peak flow meter still has a role inhome monitoring, but the physician should interpret the resultscarefully.
Comparison of pulmonary functions of thalassemic and of healthy children Mardjanis Said; Sudigdo Sastroasmoro; Djajadiman Gatot; Bambang Supriyatno; Yovita Ananta
Paediatrica Indonesiana Vol 45 No 1 (2005): January 2005
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (411.462 KB) | DOI: 10.14238/pi45.1.2005.1-6

Abstract

Objectives The aim of this study was to compare some pulmo-nary functions of thalassemic patients and those of normal chil-dren. Factors correlated with lung dysfunction were assessed.Methods This cross-sectional study compared some pulmonaryfunctions of thalassemic patients with those of healthy children.The study was performed in the Department of Child Health, CiptoMangunkusumo Hospital, Jakarta, Indonesia. Pre- and post-trans-fusion hemoglobin levels of the thalassemic subjects were deter-mined. Other data such as chelation therapy and serum ferritinlevels were also obtained. Both thalassemic and control subjectsunderwent routine physical examinations and lung function testsusing an electronic spirometer. Spirometry was repeated threetimes for each subject, and only the best result was recorded.Results Sixty-three thalassemic patients were enrolled, consist-ing of 32 male and 31 female subjects. Healthy subjects consistedof 31 males and 31 females. Most thalassemic patients (46/63)were found to have lung function abnormalities. This was signifi-cantly different from control subjects, of whom most (39/62) hadnormal lung function. Restrictive lung function abnormality was themost common (42/63) observation documented. Serum ferritin lev-els were obtained from 28 male and 29 female thalassemic sub-jects. There was no correlation between percentage from predictedforced vital capacity and serum ferritin levels, whether in male(r=0.191; P=0.967) or female (r =-0.076, P=0.695) thalassemicsubjects.Conclusion Thalassemic patients have significantly lower lungfunction than healthy children. More thalassemic patients had lungfunction abnormalities compared to healthy children. Restrictivedysfunction was the most common finding in the thalassemic group.No correlation was found between lung function and serum ferritinlevels
Co-Authors Badriul Hegar Bambang Supriyatno Diah Rini Djajadiman Gatot Mardjanis Said Sudigdo Sastroasmoro