Garuda - Garba Rujukan Digital

p-Index From 2020 - 2025

0.23

P-Index

This Author published in this journals

All Journal Jurnal Farmamedika (Pharmamedica Journal) Riset Informasi Kesehatan PharmaCine : Journal of Pharmacy, Medical and Health Science

Padmono Citroreksoko

Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Author-ID : 3460208

Humanities Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 4 Documents Claim Missing Document

Claim Missing Document

Articles

EFEKTIVITAS SALEP EKSTRAK ETANOL DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) TERHADAP PROSES PENYEMBUHAN LUKA GORES PADA KELINCI Ferry Effendi; Padmono Citroreksoko; Deo Subagyo
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 2 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Anredera cordifolia (Ten.) Steenis that is known by the name of binahong leaves have medicinal properties traditionally as wound healing. This study aims to determine the effectiveness of leaf binahong extract ointment on graze and to know the effectiveness of the leaf binahong extract ointment as wound healing. This research used experimental research method. Simplicia powder of binahong leaf was extracted using a maceration method. The result of maceration extracted by using a rotary evaporator, the extract obtained are formulated into ointments. Binahong leaf extract ointment made within 5 concentrations that is a concentration of 20%, 25%, 30%, 35% and 40%. The subject of research in the form of a rabbits that amount 3 tails were divided into 7 treatment groups ie negative control (ointment base), positive control (Betadine ointment), ointments leaf extract binahong 20%, ointment leaf extract binahong 25%, ointment leaf extract binahong 30%, ointment binahong 35% leaf extract and leaf extract ointment binahong 40%. Rabbits are scarred on the back with a wound length of 2 cm. Ointment leaf extract with various concentrations carried out the effectiveness test against the healing of scratch on the back of a rabbit that has been injured. On testing ointment was done organoleptic test, homogeneity test and pH test. The data were processed statistically using ANOVA analysis with SPSS method. Results of the research and the results of statistical analysis that extract ointment. Binahong leaf had effectivity on a scratch wound. Binahong leaf extract ointment concentration of 20%, 25% and 30% have given the effect of wound healing, where as the concentration of 35% and 40% give a more effective healing effect. Effects similar to the positive control, namely ointment binahong leaf extract with a concentration of 35%, whereas the leaf extract ointment binahong 40% have the best effect.

UJI ANTIOKSIDAN EKSTRAK PIGMEN KAROTENOID DAN SITRULIN PADA KULIT BUAH BLEWAH (Cucumis melo L.) SECARA IN VITRO (METODE DPPH) Antonius Padua Ratu; Nadia Fahmi Silabi; Padmono Citroreksoko
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 1 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Antioxidants stabilize free radicals with a complete the lack of electrons from free radicals and inhibiting the chain reaction of free radical formation. The purpose this research is to determine the amount of the antioxidant potential of the cantaloupe skin extracts and the effect of different test result of pigment carotene and citrulline in skin cantaloupe extracts to the extraction stage. Cantaloupe skin with drying and without drying treatment is gradually extracted using three solvents (petroleum ether-acetone-water). The highest antioxidant activity shown by extracts water without drying treatment (667.30 mg / L), which was significantly different (P <0.05) with acetone and petroleum ether (996.65 and 2368.26 mg / L). Treatment with drying only on petroleum ether extract (1607.28 mg / L), which provides activity compared with acetone and water (2871.54 and 2290.75 mg / L). However, cantaloupe skin extract antioxidant activity was lower compared with β-carotene and vitamin C. Treatment without drying also give the highest pigments carotenoid shown by extracts aceton (β-caroten 11,32 mg/L, lycopene 0,29 mg/100g) and level of citrulline in water extracts (29,91 mg/L). The difference of effect in simplisia treatment and solvent on the activity of antioxidants and pigments carotenoid levels were significantly different (P <0.05), whereas the levels of citrulline in the simplisia treatment was not significantly different for solvent acetone and significantly different (P <0.05) for solvent petroleum ether and water.

Toksisitas kombinasi ekstrak etanol 70% daun petai cina (Leucaena leucocephala (Lam.) de Wit) dan kulit jengkol (Archidendron jiringa (Jack) I.C.Nielsen) dengan metode Brine Shrimp Lethality Test Harry Noviardi; Sitaresmi Yuningtyas; Diah Ajeng Tri R; Ahmad Ben; Padmono Citroreksoko
Riset Informasi Kesehatan Vol 8 No 1 (2019): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Latar Belakang: Daun Petai cina dan kulit jengkol merupakan tumbuhan suku polong-polongan yang mengandung senyawa bahan alam seperti alkaloid, flavonoid, saponin, tanin dan triterpenoid. Senyawa bahan alam tersebut diduga berpotensi sebagai antikanker.Uji toksisitas digunakan untuk mendeteksi potensi senyawa antikanker.Tujuan penelitian ini adalah untuk menentukan nilai toksisitas dari kombinasi ekstrak daun petai cina dan kulit jengkol. Metode:Proses ekstraksi menggunakan daun petai cina dan kulit jengkol yang digunakan secara berturut-turut 1:1, 1:3, 1:5, 1:7, dan 1:9. Metode toksisitas yang digunakan adalah Brine Shrimp Lethality Test (BSLT)dengan hewan uji Artemia salina L. Parameter yang diukur adalah nilai lethal concentration (LC50). Hasil:Nilai LC50 yang diperoleh dari kombinasi ekstrak daun petai cina dan kulit jengkol 1:1, 1:3, 1:5, 1:7 dan 1:9 secara berturut-turut sebesar 85.27, 30.41, 21.76, 14.06 & 1.358 ppm. Hasil penelitian ini menunjukkan semua kombinasi ekstrak daun petai cina dan kulit jengkol termasuk dalam kategori sangat toksik. Kesimpulan:Kombinasi ekstrak daun petai cina dan kulit jengkol memberikan efek sangat toksik yang diduga berpotensi sebagai antikanker.

Uji Aktivitas Penghambatan Enzim Tirosinase Serta Uji Iritasi Sediaan Masker Peel-Off Ekstrak Etanol Daun Sukun (Artocarpus Altilis F) Devi Ratnasari; Fiona Rosa Sofyanita; Padmono Citroreksoko
PharmaCine : Journal of Pharmacy, Medical and Health Science Vol 1 No 1 (2020): PharmaCine: Journal of Pharmacy, Medical and Health Science
Publisher : Program Studi Farmasi Fakultas Ilmu Kesehatan Universitas Singaperbangsa Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35706/pc.v1i1.4419

Abstrak : Daun sukun (Artocarpus altilis F) diketahui memiliki senyawa metabolit sekunder salah satunya adalah flavonoid. Pada penelitian ini ekstrak etanol 96% daun sukun (Artocarpus altilis F) dan sediaan masker peel-off ekstrak etanol 96% Artocarpus alitilis diuji aktivitas penghambatan enzim tirosinase menggunakan substrat L-tirosin dan L-dopa. Hasil uji aktivitas penghambatan enzim tirosinase menunjukkan bahwa ekstrak dan sediaan tidak memiliki kemampuan penghambatan terhadap melanin yang dilihat dari nilai . Ekstrak etanol 96% daun sukun memiliki nilai dengan substrat L-tirosin sebesar 4889,467 ppm dan substrat L-Dopa sebesar 6916,626 ppm. Sediaan masker peel-off memiliki nilai dengan substrat L-tirosin sebesar 12680,48 dan untuk substrat L-Dopa sebesar 33402,96 ppm. Dilakukan uji iritasi primer pada sediaan masker peel-off ekstrak etanol daun sukun. Hasil uji iritasi primer tidak menunjukkan adanya iritasi pada kulit seperti edema, maupun eritema. Kata Kunci: Ekstrak etanol 96%, Daun sukun, Masker peel-off, Enzim tirosinase.

Co-Authors Ahmad Ben Antonius Padua Ratu Deo Subagyo Devi Ratnasari Diah Ajeng Tri R Ferry Effendi Fiona Rosa Sofyanita Harry Noviardi Nadia Fahmi Silabi Sitaresmi Yuningtyas

Title

Found 4 Documents
Search

Abstract

Abstract

Abstract

Abstract

Title Search

Found 4 Documents Search

Abstract

Abstract

Abstract

Abstract

Title

Found 4 Documents
Search