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M. Rio Radhi
Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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UJI ANTIOKSIDAN EKSTRAK AIR DAN EKSTRAK ETANOL DAGING DAN KULIT BUAH BLEWAH (Cucumis melo L.) Antonius Padua Ratu; Herson Cahaya Himawan; M. Rio Radhi
Jurnal Farmamedika (Pharmamedika Journal) Vol 2 No 1 (2017): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (426.84 KB) | DOI: 10.47219/ath.v2i1.24

Abstract

High content of sitrulin can contribute to oxidative stress as a free radical scavenger. Plants from the Cucurbitaceae family are found in high quantities of Citrulline. One of Cucurbitaceae family is cantaloupe (Cucumis melo L.) The purpose of this study was to determine the antioxidant activity which is optimal in the flesh and rind cantaloupe against extraction methods. The method was used maceration with the ethanol and water, methods of digestion and decocta only with water solvent. The high antioxidant activity was shown by ethanol extract cantaloupe was rind maceration method (583.19 mg/L). In the water extract, rind maceration method of cantaloupe provides antioxidant activity (722.17 mg/L) were significantly different (P<0,05) than the water solvent digestion method and decocta method. However, the antioxidant activity of the flesh and rind extract from cantaloupe is lower than vitamin C.
ANALISIS SENYAWA SITRULIN EKSTRAK AIR DAN EKSTRAK ETANOL DAGING DAN KULIT BUAH BLEWAH (Cucumis melo L.) Antonius Padua Ratu; Herson Cahaya Himawan; M. Rio Radhi
Jurnal Farmamedika (Pharmamedika Journal) Vol 1 No 2 (2016): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.291 KB) | DOI: 10.47219/ath.v1i2.45

Abstract

Data from the United States Department of Agriculture (USDA) National Nutrient database, that cantaloupe contains amino acids of 0.8 grams / 100 grams. One of the amino acids found in cantaloupe is citrulline which can contribute to oxidative stress as a free radical scavenger. The purpose of this study was to obtain the optimal content of citrulline compound in the flesh and skin of blewah to the method of extraction. The method used is the maceration method with ethanol and water solvent, digestion and dekokta method only with water solvent. Quantitatively, sitrulin is obtained by acid hydrolysis and is reacted with a specific reagent which is 3% diacetyl monoxime in a hot temperature. The reading of the result using the maximum wavelength spectrophotometer is 488 nm. The highest content of citrulline compound was shown by decocta method of aquatic leather water extract (7.72 g / 100g). The citrulline content was significantly different (P <0.05) on the difference in other extraction methods.
Co-Authors Antonius Padua Ratu Herson Cahaya Himawan