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All Journal Jurnal Farmamedika (Pharmamedica Journal)
Halimatussa’diyah
Sekolah Tinggi Teknologi Industri dan Farmasi Bogor
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

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EFEKTIVITAS PENYEMBUHAN LUKA TERBUKA PADA KELINCI DARI FORMULASI SALEP EKSTRAK ETANOL DAUN BABADOTAN (Ageratum conyzoides L.) Ferry Effendi; Halimatussa’diyah; Sri Helmina
Jurnal Farmamedika (Pharmamedika Journal) Vol 2 No 1 (2017): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (329.633 KB) | DOI: 10.47219/ath.v2i1.26

Abstract

Conyzoides ageratum L. known as babadotan leaves is herbal medicine which been used to threat a variety of diseases, including drugs open wounds. Previous research states that the ethyl acetate extract of babadotan leaves real healing effect (significant) on an open wound that is at a concentration of 40% and 80%. Based on that, do preliminary research aims to determine the effectiveness of the ointment preparations ethanolic extract of babadotan leaves (Ageratum conyzoides L.) against the open wound healing in rabbits. This type of research is a laboratory experiment. Simplicia babadotan leaf powder extracted using maceration methods. Babadotan leaf ethanolic extract ointment made within 5 concentration that is 30%, 35%, 40%, 45% and 50%. On testing ointment organoleptic test, homogeneity test, dispersive power test and pH test. Test the effectiveness of healing of open wounds using seven groups: negative control (without treatment), positive control (povidone iodine), ointments ethanol extract of babadotan leaves (SEDB) 30%, 35% SEDB, SEDB 40%, SEDB 45%, 50% SEDB against 3 white rabbits weighing 3-3.5 kg and a length of 1.5 cm open wound, was done and observed until 8 days. The data were processed statistically using One Way ANOVA (Analysis Of Variant). These results indicate that leaf ethanolic extract ointment babadotan 40%, 45% and 50% has a healing effect on open wounds in rabbits, the effect is almost similar to the positive control which leaves extract ointment babadotan with a concentration of 45%, while the ointment babadotan leaf extracts that provide the most excellent effect that an ointment at a concentration of 50%.
PERBANDINGAN PENURUNAN TEKANAN DARAH PASIEN BEDAH FRAKTUR DENGAN PREMEDIKASI ANESTESI PETIDIN DAN FENTANIL DI RSUD KOTA BOGOR Siti Mariam; Kiki Fitriana Dewi; Halimatussa’diyah
Jurnal Farmamedika (Pharmamedika Journal) Vol 4 No 1 (2019): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.598 KB) | DOI: 10.47219/ath.v4i1.54

Abstract

Premedication of intravenous anesthesia using the drugs petidine and fentanyl causes side effects of hypoventilation or decreased tidal volume and hypotension. This study aims to determine the decrease in blood pressure in fracture surgery patients at RSUD Kota Bogor. This study was conducted on 100 inpatients in the January-December 2018 period who were given the drugs petidine and fentanyl premedication. This type of non-experimental research with the retrospective data collection, research data were analyzed using the Kolmogorov-Sminorv test and the Mann Whitney test. Data taken included: Medical record number, age, sex, duration of surgery and blood pressure 5 minutes before premedication to 1 hour of surgery. The results found more surgical fracture patients occur in men (63%) with an age range of 40-50 years (29%). The duration of the most operations was 1 hour (62%). The most widely used premedication therapy as a narcotic analgesic drug is fentanyl (70%). The most common decrease in blood pressure is petidine (13.93 mmHg) compared to fentanyl (8.34 mm / Hg). Based on statistical results using the Kolmograv-Smirnov test and the Mann-Whitey test p-value (asymp sig. (2-tailed) showed a p-value of 0.05 (0,000) which means that there is a difference in blood pressure reduction between petidine and fentanyl.
PENGUJIAN AKTIVITAS ANTIOKSIDAN PADA EKSTRAK ETANOL DAUN AFRIKA (Gymnanthemum amygdalinum Del.) DENGAN METODE DPPH TERHADAP SEDIAAN KOSMETIK PEMBERSIH Halimatussa’diyah; Eem Masaenah; Dea Anisa Putri
Jurnal Farmamedika (Pharmamedika Journal) Vol 9 No 1 (2024): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v9i1.310

Abstract

Salah satu tanaman Indonesia memiliki zat aktif yang bermanfaat untuk esehatan kulit adalah Daun Afrika (Gymnanthemum amygdalinum Del.). Pengujian aktivitas antioksidan ekstrak etanol Daun Afrika dalam bentuk tiga formulasi sediaan sabun mandi cair dengan konsentrasi ekstrak (3%), (6%), dan (9%) metode yang dilakukan menggunakan pereaksi DPPH (2,2- diphenyl-1-picrylhydrazyl). Data yang diperoleh menunjukkan nilai IC50 ekstrak etanol daun afrika adalah 107,839 ppm. Serta nilai IC50 vitamin C sebagai kontrol positif sebesar 5,739 ppm. Formulasi ke tiga memiliki nilai IC50 261,305 ppm dengan potensi antioksidan bersifat kuat. Sediaan sabun mandi cair ekstrak etanol daun afrika dilakukan uji evaluasi mutu fisik, hasil evaluasi menunjukkan sabun mandi cair sudah memenuhi mutu fisik yang baik menurut SNI 06-4085-1996.
Co-Authors Dea Anisa Putri Eem Masaenah Ferry Effendi Kiki Fitriana Dewi Siti Mariam Sri Helmina