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Sri Rezeki Hadinegoro
Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Health Professions Medicine & Pharmacology

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Features of patients with malaria treated at the Department of Child Health Cipto Mangunkusumo Hospital, Jakarta Diana Mettadewi Jong; Hindra Irawan Satari; Sri Rezeki Hadinegoro; Sumarmo Soedarmo; Hardjono Abdoerrachman; Alan R. Tumbelaka
Paediatrica Indonesiana Vol 42 No 9-10 (2002): September 2002
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.608 KB) | DOI: 10.14238/pi42.5.2002.217-9

Abstract

Background Malaria is endemic throughout the tropical areas of the world. In Jakarta, one of the cities in Indonesia that has been declared to be free of malaria, malaria was found in 1044 patients from 1974 to 1990. All patients were infected in other areas.Objective To describe the clinical features of malaria in the Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta.Methods A retrospective study was carried out on all patients with malaria treated at the Department of Child Health, Cipto Mangunkusumo Hospital, Jakarta, from January 1995 to December 2000.Results There were 10 inpatients and 5 outpatients with malaria eligible in this study. Most patients (13) were boys, and 8 patients aged 5-9 years. We found falciparum malaria in 5, one of which with cerebral malaria, vivax in 3 patients, and mixed infection in 4 patients. In 3 patients, the type of malaria could not be detected. Three out of the referred patients were referred with the diagnosis of leukemia. Fever, splenomegaly, and pale were found in most patients. All inpatients recovered completely on discharge.Conclusions In malaria-free areas, all patients were infected in other areas and some were referred with misdiagnoses. Malaria should be considered in patients with fever or pale and organomegaly.
Absorption of carbohydrate derived from rice in children aged 1-3 years Agus Firmansyah; Daniel Effendi; Sri Rezeki Hadinegoro; Aswitha Boediarso; Badriul Hegar Syarif; Pramitra Gayatri
Paediatrica Indonesiana Vol 41 No 5-6 (2001): May 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.3.2001.132-40

Abstract

Many studies showsthat rice starch is well-absorbed in gastrointestinaltract, even better as a composition with electrolyte to overcome diarrhea. Although in small number, there is still a various prevalence of carbohydrate malabsorption, both with rice starch and with other starch. Khin-Maung-U found significant (66.5%) prevalence of rice starch in Burmese children malabsorption, whereas rice starch is readily obtained in countries with rice as the population staple food,so thatability to absorb rice starch in Indonesian children need to be studied. Breath hydrogen test (BHT) was performed in 86 Indonesian children aged 1-3 years on Pejaten Barat Subdistrict, Pasar Minggu, South Jakarta. Among the 86 children given meal test with rice starch cakes 80 g for eachchildren, 82 children (95.3%) can absorb rice starch well, but 4 children (4.7%) suffered from rice starch alabsorption. Currentlyit is unknown certainly the type of the malabsorption. Previous researchers found that rice malabsorption is due to enzyme deficiency and intestinal motility disturbance. In this study there were 16 children (18.6%) coming from social-economically underprivileged family, most of the mothers with junior high school and lower educational level, and the majority of parent occupation were on private and labor sectors. There was no significant relation (p >0.05) between diarrhea effects on rice starch malabsorption in 6 children (7%), history of low birth weight baby (15.1%), undernourished or malnutrition status in 35 children (40.7%), and worm and/or fungal infection in 17 children (19.8%).found that rice malabsorption is due to enzyme deficiency and intestinal motility disturbance. In this study there were 16children (18.6%) coming from social-economically underprivileged family, most of the mothers with junior high school andlower educational level, and the majority of parent occupation were on private and labor sectors. There was no significantrelation (p >0.05) between diarrhea effects on rice starch malabsorption in 6 children (7%), history of low birth weight baby(15.1%), undernourished or malnutrition status in 35 children (40.7%), and worm and/or fungal infection in 17 children(19.8%). [
Clinical and laboratory features of typhoid fever in childhood Sylvia Retnosari; Alan R. Tumbelaka; Arwin P. Akib; Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 41 No 5-6 (2001): May 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (137.445 KB) | DOI: 10.14238/pi41.3.2001.149-54

Abstract

The aims of the study were to review the clinical features of patient with suspected typhoid fever, to obtain features of the blood culture results, Widal, Typhidot tests and to identify the relationship between/prior antibiotic administration with laboratory findings. The study had been conducted since January 1, 1999 till January 31, 2000 with inclusion criteria (1) age of patient was 3 to 14 years, (2) patient with diagnosis of suspected typhoid fever and (3) gave consent to participate in the present study. Thirty-six patients were eligible for this study and the result showed that typhoid fever was encountered more commonly in girls with the most prevalent onset was in age 5 to 9 years and duration of fever was less than 8 days. Gastrointestinal tract disturbance was the most frequent complain after fever. Most patient showed negative results in blood culture examination and Widal test, and gave positive results in Typhidot/Typhidot M test as well. Antibiotic administration tended to influence blood culture and Widal test as to need consideration in evaluation of laboratory results. However, a conclusion still could not be drawn definitively that further study with adequate sample number and positive blood culture as criteria inclusion was needed. 
Varicella antibody in healthy children Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 39 No 1-2 (1999): January - February 1999
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (582.433 KB) | DOI: 10.14238/pi39.1-2.1999.1-7

Abstract

Varicella is the most contagious viral exanthematous disease, which has a variable clinical course. We studied a seroepiderniologicaJ study on varicella antibody in 350 healthy children at Department of Child Health, Medical School, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta; from May to July 1998. The aim of this study was to get figures of varicella antibody in healthy chiJdren which can be used as a baseline data in the decision of recommendation in varicella vaccination. Subjects were 1-12 years old children with no history of varicella infection or immunization. The varicella antibody was determined by using Etisa assay (Enzygnost lest). Among 350 healthy children, 42.9% were males; they were divided into 3 age groups: 1-3, 4-7 and 8-12 years. Fourty two children (11.1 %) had seropositive varicella antibody (above protective level 0.2 mIU/ml). The prevalence of subclinical valicella significance increased with increasing age. Subjects with clinical or subclinical varicella had the same figure of age specific prevalence. The mean varicella antibody in each age group was almost similar. The minimum varicella antibody titer was quite similar between 1-3 and 4-7 age group, but not in 8-12 age group. Forty one percent had history of varicella contact, older chiildren had more history of contact.
Exposure pattern of house dust mites in childhood asthma along the year: A series of 10 cases Zakiudin Munasir; Lenny S. Budi; Titi Sularyo; Sri Rezeki Hadinegoro
Paediatrica Indonesiana Vol 39 No 7-8 (1999): July - August 1999
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (691.456 KB) | DOI: 10.14238/pi39.7-8.1999.201-10

Abstract

House dust mite (HDM) is one of the inhalant allergens causinginflammation of respiratory tract. More than 100 dust mites/ gram house dust may cause sensitization in childhood asthma, while more than >500 house dust mite/gram house dust may cause asthma attack. This report aimed to determine the exposure pattern of house dust mites on 10 asthmatic children during one year. Homevisit to all patients was done every month to obtain house dust sample, measurement of relative humidity, bed room temperature, and to evaluate the clinical scores and peak expiratory flow rate (PEFR). The range value of house dust mite/gram house dust was 0-340. This study shows that house dust mite may cause of acute asthma attack when accompanied by nonspesific stimuli. In September the relative humidity is high, the temperature is low, and the amount of house dust mite/gram of house dust is highest, in contrast to in August and December. This study shows no seasonalvariation. The amount of house dust mite/ gram of house dust was found higher at the mattress than in the floor of bed room. The species of house dust mite that predominantly found is Dermato- phagoides pteronyssinus. We conclude that house dust mite may cause acute asthma attack whenever accompanied by nonspesific stimulus.
Co-Authors Agus Firmansyah Alan R. Tumbelaka Arwin P. Akib Aswitha Boediarso Badriul Hegar Syarif Daniel Effendi Diana Mettadewi Jong Hardjono Abdoerrachman Hindra Irawan Satari Lenny S. Budi Pramitra Gayatri Sumarmo Soedarmo Sylvia Retnosari Titi Sularyo Zakiudin Munasir