Badriul Hegar Syarif
Department Of Child Health, University Of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta

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Konstipasi Fungsional Bernie Endyarni; Badriul Hegar Syarif
Sari Pediatri Vol 6, No 2 (2004)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (178.914 KB) | DOI: 10.14238/sp6.2.2004.75-80

Abstract

Konstipasi merupakan keadaan yang sering ditemukan pada anak dan dapat menimbulkanmasalah sosial maupun psikologis. Berdasarkan patofisiologis, konstipasi dapatdiklasifikasikan menjadi konstipasi akibat kelainan struktural dan konstipasi fungsional.Konstipasi yang dikeluhkan oleh sebagian besar pasien umumnya konstipasi fungsionalyang dihubungkan dengan adanya gangguan motilitas kolon atau anorektal. Konstipasikronis yaitu kostipasi yang telah berlangsung lebih dari 4 minggu. Dalam mentukanadanya konstipasi terdapat 3 aspek yang perlu diperhatikan, yaitu frekuensi buang airbesar (b.a.b), konsistensi tinja, dan temuan pada pemeriksaan fisis. Para ahligastroenterologi di Eropa dan Amerika telah membuat satu kriteria untuk yangmenentukan adanya konstipasi fungsional, yang dikenal dengan kriteria Roma. Meskipunmasih terus dalam pengkajian, beberapa negara telah menggunakan kriteria tersebutsebagai upaya menentukan adanya konstipasi fungsional. Dalam menangani anak dengankonstipasi perlu ditekankan tentang pentingnya hubungan yang erat antara dokter,orangtua, dan pasien. Pada dasarnya, terapi konstipasi terdiri dari dua fase, yaitu fasepengeluaran masa tinja dan fase pemeliharaan. Catatan harian tentang b.a.b, latihanb.a.b (toilet training), makan makanan berserat, terapi laksatif, serta pendekatan secarapsikiatri/psikologi merupakan upaya yang perlu dilaksanakan untuk memperoleh hasilyang optimal.
Penilaian Aktivitas Penyakit Lupus Eritematosus Sistemik dengan Skor SLEDAI di Departemen Ilmu Kesehatan Anak RSCM Anisah M. Saleh; Nia Kurniati; Badriul Hegar Syarif
Sari Pediatri Vol 16, No 4 (2014)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp16.4.2014.292-8

Abstract

Latar belakang. Keberhasilan tata laksana penyakit lupus eritematosus sistemik (LES) memerlukanpemantauan tertentu. Skor systemic lupus erythematosus disease activity index (SLEDAI) adalah alat ukuryang dapat digunakan untuk tata laksana sehari-hari. Saat ini belum ada data mengenai pemantauan aktivitaspenyakit LES anak menggunakan skor SLEDAI dengan rentang waktu tertentu.Tujuan. Memantau aktivitas penyakit LES anak dengan skor SLEDAI setiap 3 bulan selama satu tahunpengamatan.Metode. Studi deskriptif retrospektif menggunakan data rekam medik dari 01 Juli 2005 sampai dengan31 Juli 2013.Hasil. Tigapuluh rekam medik memenuhi kriteria penelitian. Manifestasi awal tersering berdasarkan skorSLEDAI adalah artritis, rash, demam, peningkatan dsDNA, dan komplemen darah rendah. Perubahan skorSLEDAI terutama terlihat pada pengamatan antara bulan ke-0 dengan bulan ke-3. Pada awal pengamatan,mayoritas pasien termasuk high activity, tetapi pada akhir pengamatan menjadi no activity.Kesimpulan. Penilaian skor SLEDAI setiap 3 bulan dapat digunakan untuk memantau aktivitas penyakitLES anak.
Absorption of carbohydrate derived from rice in children aged 1-3 years Agus Firmansyah; Daniel Effendi; Sri Rezeki Hadinegoro; Aswitha Boediarso; Badriul Hegar Syarif; Pramitra Gayatri
Paediatrica Indonesiana Vol 41 No 5-6 (2001): May 2001
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi41.3.2001.132-40

Abstract

Many studies showsthat rice starch is well-absorbed in gastrointestinaltract, even better as a composition with electrolyte to overcome diarrhea. Although in small number, there is still a various prevalence of carbohydrate malabsorption, both with rice starch and with other starch. Khin-Maung-U found significant (66.5%) prevalence of rice starch in Burmese children malabsorption, whereas rice starch is readily obtained in countries with rice as the population staple food,so thatability to absorb rice starch in Indonesian children need to be studied. Breath hydrogen test (BHT) was performed in 86 Indonesian children aged 1-3 years on Pejaten Barat Subdistrict, Pasar Minggu, South Jakarta. Among the 86 children given meal test with rice starch cakes 80 g for eachchildren, 82 children (95.3%) can absorb rice starch well, but 4 children (4.7%) suffered from rice starch alabsorption. Currentlyit is unknown certainly the type of the malabsorption. Previous researchers found that rice malabsorption is due to enzyme deficiency and intestinal motility disturbance. In this study there were 16 children (18.6%) coming from social-economically underprivileged family, most of the mothers with junior high school and lower educational level, and the majority of parent occupation were on private and labor sectors. There was no significant relation (p >0.05) between diarrhea effects on rice starch malabsorption in 6 children (7%), history of low birth weight baby (15.1%), undernourished or malnutrition status in 35 children (40.7%), and worm and/or fungal infection in 17 children (19.8%).found that rice malabsorption is due to enzyme deficiency and intestinal motility disturbance. In this study there were 16children (18.6%) coming from social-economically underprivileged family, most of the mothers with junior high school andlower educational level, and the majority of parent occupation were on private and labor sectors. There was no significantrelation (p >0.05) between diarrhea effects on rice starch malabsorption in 6 children (7%), history of low birth weight baby(15.1%), undernourished or malnutrition status in 35 children (40.7%), and worm and/or fungal infection in 17 children(19.8%). [
Evaluation of Bio M pylori serologic test and C-13 urea breath test for H. pylori infection in children with recurrent abdominal pain: a pilot study Mira Dewita; Badriul Hegar Syarif; Sudigdo Sastroasmoro
Paediatrica Indonesiana Vol 50 No 2 (2010): March 2010
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi50.2.2010.101-104

Abstract

Background Diagnosing Helicobacter pylori infection in childrenis still a problem. Urea breath test is the gold standard for noninvasivediagnostic test, but it is expensive and not available inmost hospitals. The Bio M Pylori serologic test has good diagnosticvalue in adults, less expensive and more practical, but had neverbeen evaluated in children.Objective To determine the prevalence of H. pylori infection andthe diagnostic accuracy of Bio M Pylori serologic test in childrenwith recurrent abdominal pain.Methods This study was conducted in May - June 2009. Childrenaged 12-15 years with recurrent abdominal pain were examinedwith urea breath test and the Bio M Pylori serologic test.Sensitivity, specificity, area under the curve (AUC), predictivevalues, and likelihood ratios were calculated for the Bio M Pyloriserologic test.Results Most subjects aged 13 years (83%). Girls outnumberedboys, and most were undernourished. The prevalence ofH. pyloriinfection detected by urea breath test and Bio M Pylori serologictest was 8% and 52%, respectively. The Bio M Pylori serologictest had sensitivity and specificity of 100% and 53%, respectively.Area under the curve (AUC) was 0.764. Positive and negativepredictive values were 16 and 100%, whereas positive andnegative likelihood ratios are 2.12 and 0. The overall accuracyof this test is 5 7%Conclusions The Bio M Pylori serologic test has high sensitivityvalue (100%). This diagnostic kit can be considered as a goodpre-endoscopic screening tool in children with recurrentabdominal pain caused by H. pylori infection.
Factors affecting exclusive breastfeeding in term infants Novitria Dwinanda; Badriul Hegar Syarif; Damayanti Rusli Sjarif
Paediatrica Indonesiana Vol 58 No 1 (2018): January 2018
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (81.408 KB) | DOI: 10.14238/pi58.1.2018.25-35

Abstract

Background Exclusive breastfeeding by healthy mothers to their healthy, term babies who underwent vaginal birth, should be readily accomplished. However, exclusive breastfeeding by Indonesian mothers has declined.Objective To assess the monthly success rate prevalences for exclusive breastfeeding for the first 6 months of life, as well as factors that affect exclusive breastfeeding.Methods A prospective cohort study was conducted in 243 healthy mothers with healthy term babies who underwent normal births at Cipto Mangunkusumo Hospital (CMH), Jakarta, Indonesia. Guided interviews were conducted monthly for six months. Bivariate and multivariate analyses were performed on the factors potentially affecting breastfeeding with equal subject numbers.Results Exclusive breastfeeding prevalences were 64.8% (first month), 53.7% (second month), 43% (third month), 30.7% (fourth month), 23.5% (fifth month), and 22.3% (sixth month). Multivariate analysis revealed that the mother’s confidence in breast milk production, as well as husband or family support, affected the success of exclusive breastfeeding for each month. Maternal not working/studying outside the home affected the success of exclusive breastfeeding in the third (RR 3.38; 95%CI 1.21 to 9.43) and fourth months (RR 6.56; 95%CI 1.39 to 30.99).Conclusion Exclusive breastfeeding prevalences in Cipto Mangunkusumo Hospital decrease in a monthly fashion up to the sixth month. Several factors affecte the success rate for each month in the six month period, including maternal confidence in breast milk production and family support.
Kepatuhan Pengobatan Sebagai Faktor Proteksi terhadap Kualitas Hidup pada Anak dan Remaja dengan Penyakit Graves Ismail, Ismi Citra; Soesanti, Frida; Syarif, Badriul Hegar; Medise, Bernie Endyarni; Pulungan, Aman Bhakti; Bermanshah, Evita Karianni; Faizi, Muhammad
Sari Pediatri Vol 27, No 2 (2025)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp27.2.2025.73-81

Abstract

Latar belakang. Penyakit Graves (PG) merupakan kelainan autoimun yang merupakan penyebab hipertiroid terbanyak pada anak dan remaja. Manifestasi PG dan proses pengobatan yang dilakukan pasien akan memberikan dampak pada kualitas hidup pasien. Kepatuhan pasien terhadap pengobatan akan memengaruhi keberhasilan pengobatan dan kualitas hidup.Tujuan. Penelitian ini dilakukan untuk mengetahui hubungan antara kepatuhan pengobatan dengan kualitas hidup pada pasien anak dan remaja dengan PG.Metode. Studi potong lintang terhadap 74 anak usia 5-18 tahun dengan PG. Pemilihan subjek secara consecutive sampling mulai Desember 2020 – Mei 2021. Kepatuhan pengobatan diukur dengan The Morisky Medication Adherence Scale (MMAS-8), kualitas hidup diukur dengan The Pediatric Quality of Life Inventory (PedsQLTM) Analisis hubungan antara kepatuhan pengobatan dengan kualitas hidup setelah menyesuaikan dengan variabel perancu dilakukan dengan metode regresi logistik.Hasil. Tingkat kepatuhan pengobatan tinggi pada pasien anak dan remaja dengan PG adalah 21,6 %. Prevalens kualitas hidup terganggu pada anak dan remaja dengan PG adalah 45,9% dan tidak ada beda antara laporan anak dan orangtua. Nilai adjusted OR kepatuhan pengobatan tinggi untuk terjadinya kualitas hidup terganggu setelah menyesuaikan dengan tingkat pendidikan ibu, tingkat pendapatan, usia, dan durasi sakit adalah 0,098 (IK95% = 0,016-0,580).Kesimpulan. Tingkat kepatuhan pengobatan tinggi merupakan faktor protektif dari terjadinya kualitas hidup terganggu pada anak dengan PG.