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Husein Alatan
Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Health Professions Medicine & Pharmacology

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Cyclosporin-A Treatment in Steroid Nonresponsive Nephrotic Syndrome IGN Wila Wirya; Taralan Tambunan; Husein Alatan
Paediatrica Indonesiana Vol 34 No 1-2 (1994): January - February 1994
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (394.615 KB) | DOI: 10.14238/pi34.1-2.1994.1-7

Abstract

Fifteen patients with steroid nonresponsive nephrotic syndrome (NS) aged 4-16 years received oral cyclosporin-A (CyA) for 12 weeks. Nine of the patients were boys. Out of the 15 patients, 7 were frequent relapsers, 3 were steroid dependents, 4 were steroid resistants and one with toxic steroid. After 12 weeks of CyA treatment;, 6 patients showed complete remission, 7 showed partial remission, and 2 patients did not respond at all. Side effects observed were slight renal function impairment, gingival hyperplasia, and a hump on the breast; all disappeared gradually after stopping CyA. Patients with total remission experienced relapse 2 to 12 months after discontinuation of CyA, while patients with partial remission experienced relapse 2 weeks to 3 months after CyA was discontinued A tentative conclusion can be drawn that CyA is a good alternative in the treatment of idiopathic NS, especially in steroid dependent patients who are at risk of developing steroid toxicity. CyA represent a major advance in the treatment selected SN patients who have failed with the conventional modes of therapy.
Studies of Blood Pressure and Prevalence of Hypertension in Schoolchildren in Jakarta I. G. N. Wila Wirya; Husein Alatan; Taralan Tambunan; S. Harmanses; Endang Windiastuti
Paediatrica Indonesiana Vol 28 No 9-10 (1988): September - October 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.088 KB) | DOI: 10.14238/pi28.9-10.1988.183-91

Abstract

Blood pressure measurement was done on 4983 school children of 6 - 18 years schoolchildren was at random so that the sample population represented the children in Jakarta. The incidence of hypertension in this study is about 3.11 %, of which most are found at the age of 15 years.
Co-Authors Endang Windiastuti I. G. N. Wila Wirya IGN Wila Wirya S. Harmanses Taralan Tambunan