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F. X. Santoso
and Department of Child Health, Universitas Airlangga Medical School/Dr. Soetomo General Hospital, Surabaya, East Java
Health Professions Medicine & Pharmacology

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Hereditary Spherocytosis : A Clinical Experience F. X. Santoso; Sukardi Sukardi; Bambang Permono; Netty R. H. T.; S. Untario
Paediatrica Indonesiana Vol 28 No 1-2 (1988): January - February 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (658.798 KB) | DOI: 10.14238/pi28.1-2.1988.27-35

Abstract

Although hereditary spherocytosis is a common cause of hemolytic anemia among whites of Northern European descent, it is uncommon in Asia. In the past 8.5 years (from December 1978 to June 1987), we found only six cases of hereditary spherocytosis. They were 3 males and 3 females, and their ages ranged from 3 months to 8 years, with a mean age of 3.3 years. The most common presenting complaint was anemia (6 cases) followed by jaundice (4 cases) and splenomegaly (4 cases). Other symptoms were fever, abdominal pain and hepatomegaly. The mean hemoglobin concentration of these patients was 7.5 g/dl, in which 2 patients had severe anemia (less than 6 g/dl). Reticulocyte count ranged from 1.9% to 10% (mean 5.9%). All patients were found to have spherocytosis in their peripheral blood smears and an increased red blood cell fragility. Splenectomy was performed in one patient. There was no significant complication after operation in a 7-month follow up. The clinical manifestation returned to normal and the mean hemoglobin concentration increased. The existence of hereditary spherocytosis could not be proven in almost all parents of the patients. Based on this fact, is 'congenital spherocytosis' a more suitable term instead of hereditary spherocytosis?
Laryngeal Tuberculosis in a Child (A Case Report) F. X. Santoso; Esther S. I. Witono; Makmuri M. S.; Gunadi Santosa
Paediatrica Indonesiana Vol 28 No 3-4 (1988): March - April 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (410.398 KB) | DOI: 10.14238/pi28.3-4.1988.60-6

Abstract

Since the advent of effective antituberculous chemotherapy, laryngeal tuberculosis has become relatively uncommon, and there is a real possibility that the diagnosis may be delayed or overlooked. Data from the ENT outpatient clinic Dr. Soetomo Hospital showed a significant decrease in the prevalence of laryngeal tuberculosis, from 4. 72 o/oo in 1980 to 0.28 o/oo in 1986. This condition is usually found in adult males who have pulmonary tuberculosis. A girl with laryngeal tuberculosis is the objective of the present report. The patient was admitted with a history of chronic hoarseness. With a presumptive diagnosis of papilloma of the larynx, some biopsies were performed. The histopathologic exmamintaions suggested laryngeal tuberculosis. Additional examinations revealed a positive tubercullin test, diffuse infiltrates on both lungs and positive acid fast bacilli. Her condition improved after chemotherapy administration.
Co-Authors Bambang Permono Esther S. I. Witono Gunadi Santosa Makmuri M. S. Netty R. H. T. S. Untario Sukardi Sukardi