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Netty R. H. T.
and Department of Child Health, Universitas Airlangga Medical School/Dr. Soetomo General Hospital, Surabaya, East Java
Health Professions Medicine & Pharmacology

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Hereditary Spherocytosis : A Clinical Experience F. X. Santoso; Sukardi Sukardi; Bambang Permono; Netty R. H. T.; S. Untario
Paediatrica Indonesiana Vol 28 No 1-2 (1988): January - February 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (658.798 KB) | DOI: 10.14238/pi28.1-2.1988.27-35

Abstract

Although hereditary spherocytosis is a common cause of hemolytic anemia among whites of Northern European descent, it is uncommon in Asia. In the past 8.5 years (from December 1978 to June 1987), we found only six cases of hereditary spherocytosis. They were 3 males and 3 females, and their ages ranged from 3 months to 8 years, with a mean age of 3.3 years. The most common presenting complaint was anemia (6 cases) followed by jaundice (4 cases) and splenomegaly (4 cases). Other symptoms were fever, abdominal pain and hepatomegaly. The mean hemoglobin concentration of these patients was 7.5 g/dl, in which 2 patients had severe anemia (less than 6 g/dl). Reticulocyte count ranged from 1.9% to 10% (mean 5.9%). All patients were found to have spherocytosis in their peripheral blood smears and an increased red blood cell fragility. Splenectomy was performed in one patient. There was no significant complication after operation in a 7-month follow up. The clinical manifestation returned to normal and the mean hemoglobin concentration increased. The existence of hereditary spherocytosis could not be proven in almost all parents of the patients. Based on this fact, is 'congenital spherocytosis' a more suitable term instead of hereditary spherocytosis?
Splenectomy in Idiopathic Thrombocytopenic Purpura : A Clinical Experience Indro Zaeni; Sukardi Sukardi; Bambang P.; Netty R. H. T.; S. Untario
Paediatrica Indonesiana Vol 28 No 11-12 (1988): November - December 1988
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (534.224 KB) | DOI: 10.14238/pi28.11-12.1988.259-66

Abstract

Since 1979 until 1987 there were 4 idiophatic 1hrombocytopenic purpura (ITP) cases who had undergone splenectomy, consisting of 2 males and 2 females. All patients had been treated with prednisone prior to splenectomy, 2 patients received additional cytostatics. The course of the disease prior to splenectomy had been followed in a period of time, varying from 2,5 to 8 years. The effect of treatment was not very statisfying, as both clinical and laboratory reccurrence often happened. Post spelectomy, the administration of prednisone in 1 case was stopped immediately, in 2 cases it was stopped after 8 months and in 1 case it was continued. After more than 5 years follow up, 3 cases showed excellent clinical and laboratory findings, while I case failed.
Co-Authors Bambang P. Bambang Permono F. X. Santoso Indro Zaeni S. Untario Sukardi Sukardi