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Therapeutic Effect of Topical Ointment Ethanol Extract From Patiwala Leaves (Lantana camara) on Histological Profile of Incision Wounds in Diabetic Rat Models Theosobia Grace Orno; Anita Rosanty; Ratih Feraritra Danu Atmaja; Zulfikar Ali Hasan; Tuty Yuniarty; Ahmat Rediansya Putra
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1091-1097

Abstract

Diabetic wounds are one of the neurovascular complications of diabetes. Hyperglycemia complicates the healing of diabetic wounds, which are susceptible to infection and chronic inflammation. Topical treatment using herbal extracts aims to reduce the side effects of surrounding tissue damage. A topical ointment made from ethanol extract of Patiwala (Lantana camara) leaves, which has been tested for product quality, has antibacterial and anti-inflammatory effects that has been proven to help accelerate the healing of diabetic wounds in rats through parameters such as reduced wound diameter, changes in the number of fibroblast cells, and collagen fiber formation seen in the histological profile during 21 days of therapy with a concentration of 15% (p>0.05) compared to the positive control of 10% betadine.
Peningkatan Pengetahuan Masyarakat Kelurahan Anduonohu Tentang Vaksinasi COVID-19 Menyambut Adaptasi New Normal Anita Rosanty; Theosobia Grace Orno; Tuty Yuniarty
Karya Kesehatan Siwalima Vol. 1 No. 2 (2022): September
Publisher : Lembaga Penerbitan Fakultas Kesehatan, Universitas Kristen Indonesia Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54639/kks.v1i2.803

Abstract

Covid-19 merupakan suatu penyakit yang menyerang sistem pernapasan, diketahui disebabkan oleh virus SARS-CoV-2. Indonesia termasuk salah satu negara di dunia yang masih terus berjuang untuk mengatasi pandemi COVID-19, salah satunya dengan pengembangan platform vaksin dan pelaksanaan program vaksinasi sebagai upaya pembentukan kekebalan kelompok/ herd immunity agar masyarakat dapat beraktifitas seperti biasanya/ new normal. Tujuan kegiatan ini adalah memberikan edukasi guna meningkatkan pengetahuan dan kesadaran masyarakat Kelurahan Anduonohu Kecamatan Poasia terkait program vaksinasi COVID-19. Hasil kegiatan pengabdian kepada masyarakat dengan jumlah peserta yang ikut serta dalam kegiatan sebanyak 32 orang. Kategori umur terdistribusi merata antara 30-70 tahun, peserta berjenis kelamin laki-laki sebanyak 12 orang (37%) dan perempuan sebanyak 20 orang (63%). Adanya peningkatan pengetahuan masyarakat tentang vaksinasi COVID-19 sebesar 79%. Besar harapan kami semoga dengan adanya program ini, semakin banyak masyarakat yang bersedia untuk mengikuti program vaksinasi COVID-19 sebagai bentuk persiapan memasuki adaptasi new normal.
Indeks Eritrosit sebagai Indikator Prognostik Anemia pada Pasien Gagal Ginjal Kronis dengan Hemodialisa di RSUD Bahteramas Provinsi Sulawesi Tenggara Julianti Isma Sari Usman; Anita Rosanty; Nurul Annisa Febriana Dahlan
Jurnal Analis Kesehatan Kendari Vol. 8 No. 1 (2025): Jurnal Analis Kesehatan Kendari : December 2025
Publisher : Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Chronic kidney disease is a progressive and irreversible decline in kidney function, requiring hemodialysis therapy in the end stage. One of the most common complications is anemia, which can be assessed through erythrocyte indices, including MCV, MCH, and MCHC. This study aims to determine the value of the erythrocyte index as a prognostic indicator in patients with chronic kidney failure with hemodialysis. This research is a descriptive study with a cross-sectional approach. A total of 34 patients were selected using a purposive sampling technique. Blood samples were analyzed using a Sysmex XN-1000 Hematology Analyzer. The results showed normocytic normochromic in 27 patients (79%), microcytic normochromic in 4 patients (12%), and microcytic hypochromic in 3 patients (9%). The average erythrocyte index in patients with chronic renal failure with hemodialysis was found to have an average MCV value of 86.2 fL, MCH 27.5 pg, MCHC 31.8% and hemoglobin 9.1 g/dl which indicates normocytic normochromic anemia. The conclusion of this study is that chronic kidney disease patients undergoing hemodialysis predominantly have normocytic normochromic erythrocyte indices.