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AKTIVITAS ANTIKONVULSAN EKSTRAK RIMPANG TEMU IRENG (Curcuma aeruginosa Roxb.) PADA TIKUS PUTIH JANTAN MENGGUNAKAN ELEKTROKONVULSIOMETER Agustin Yumita; Dwitiyanti Dwitiyanti; Putri Ermawati
Jurnal Ilmiah Farmasi Farmasyifa Vol 5, No 1 (2022)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiff.v5i1.8829

Abstract

Rimpang temu ireng (Curcuma aeruginosa Roxb.) diketahui memiliki kandungan metabolit sekunder yang dapat berkhasiat sebagai antikonvulsan. Penelitian ini bertujuan untuk mengetahui aktivitas antikonvulsan ekstrak etanol 70% rimpang temu ireng pada tikus putih jantan. Ekstraksi yang digunakan dalam metode ini adalah maserasi. Hewan uji diberi ekstrak etanol 70% rimpang temu ireng (100 mg/kgBB, 200 mg/kgBB, dan 400 mg/kgBB), pembanding standar asam valproate. Pengujian antikonvulsan menggunakan alat digital elektrokonvulsiometer dengan parameter yang diamati adalah onset HLE dan durasi HLE. Ekstrak etanol 70% rimpang temu ireng dosis 400 mg/kgBB memiliki aktivitas yang paling baik sebagai antikonvulsan dengan memperpanjang onset HLE dan mempersingkat durasi HLE sebanding dengan pembanding standar. Temu ireng memiliki potensi untuk dikembangkan sebagai antikonvulsan yang cukup baik.
PELATIHAN PEMBUATAN SABUN HERBAL RAMAH LINGKUNGAN DI KAMPUNG LOJI DESA GEKBRONG CIANJUR JAWA BARAT Nining Nining; Tahyatul Bariroh; Ristianti Azharita; Kori Yati; Fujianti Fujianti; Ema Dewanti; Agustin Yumita
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 6, No 4 (2022): Desember
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v6i4.11319

Abstract

ABSTRAKSabun herbal merupakan sabun yang diproduksi dari tanaman berkhasiat obat secara sederhana tanpa penambahan bahan sintetik atau bahan aditif lainnya. Kegiatan ini merupakan pelatihan dalam pembuatan sabun herbal yang ramah lingkungan kepada masyarakat Kampung Loji Desa Gekbrong Cianjur sebagai bagian yang terintegrasi dengan Kuliah Kerja Nyata Mahasiswa (KKNM) Tematik Fakultas Farmasi dan Sains UHAMKA dalam Program Kompetisi Kampus Merdeka (PKKM) tahun 2022. Tujuannya adalah untuk menyampaikan pengetahuan dan keterampilan dalam pabrikasi produk sabun herbal dengan berbagai bahan aktif seperti kopi, teh hijau, dan sereh. Kegiatan ini dilakukan dengan metode observasi dan penyuluhan secara langsung dengan sasaran masyarakat Kampung Loji. Kegiatan diawali dengan pemberian materi mengenai sabun herbal ramah lingkungan dan dilanjutkan dengan simulasi pembuatan sabun herbal menggunakan variasi bahan aktif seperti teh hijau, kopi, dan sereh. Evaluasi dilaksanakan untuk mengetahui sejauh mana pengetahuan peserta terhadap teknologi pembuatan sabun herbal yang akan dipraktikkan dan keberhasilan capaian kegiatan. Peserta sangat antusias selama kegiatan berlangsung. Secara statistik, terdapat rata-rata peningkatan nilai dari pretest ke posttest sebanyak 12,00 poin (positive ranks) dengan nilai Asymp. Sig. (2-tailed) 0,000 (p-value ≤ 0,005) menggunakan Wilcoxon Signed Ranks Test. Dengan demikian, hasil evaluasi menunjukkan strategi pelatihan dalam kegiatan ini tepat untuk diterapkan dalam rangka meningkatkan pengetahuan peserta mengenai pembuatan sabun herbal ramah lingkungan. Kata kunci: sabun herbal; ramah lingkungan; pengabdian masyarakat; kampung loji. ABSTRACTHerbal soaps are soaps that are produced from simple medicinal plants without the addition of synthetic ingredients or other additives. This activity is training in producing environmentally friendly herbal soap for the Loji community, Gekbrong Village, Cianjur, as an integrated part of the Thematic Student Real Work Lecture (KKNM) of the Faculty of Pharmacy and Science, UHAMKA in the Merdeka Campus Competition Program (PKKM) 2022. This activity applies direct observation and counselling methods with the Loji community target. This activity aims to impart knowledge and skills in producing herbal soap products with various active ingredients such as coffee, green tea, and lemongrass. The activity began with the educational delivery of environmentally friendly herbal soap. It continued with a simulation of producing herbal soap using various active ingredients such as green tea, coffee, and lemongrass. The evaluation was conducted to determine the extent of the participant's knowledge of the technology for producing herbal soap to be practiced and the success of the activities. Participants were very enthusiastic during the activity. Statistically, there is an average increase in scores from the pretest to the posttest of 12.00 points (positive ranks) with an Asymp value. Sig. (2-tailed) 0.000 (p-value 0.005) using the Wilcoxon Signed Ranks Test. Thus, the evaluation results indicate that the training strategy in this activity is appropriate to be applied to increase the participants' knowledge about producing environmentally friendly herbal soaps. Keywords: herbal soap; environmentally friendly; community dedication; loji village.
PEMANFAATAN OBAT TRADISIONAL DALAM MENGATASI DISMENOREA PADA REMAJA PUTERI SMA MUHAMMADIYAH JAKARTA TIMUR Agustin Yumita; Nora Wulandari; Rizkia Indah Tawakani
Jurnal Farmasi Klinik dan Sains Vol 2, No 2 (2022): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v2i2.979

Abstract

Dismenorea merupakan masalah ginekologi yang sering dialami remaja puteri. Penangganan dismenorea selain dengan pengobatan medis juga dapat memanfaatkan obat tradisional. Dismenorea menyebabkan beberapa masalah salah satunya mempengaruhi prestasi belajar remaja puteri di sekolah. Dalam penelitian ini bertujuan untuk melihat tingkat pengetahuan dan praktik remaja puteri dalam memanfaatkan obat  tradisional untuk mengatasi dismenorea. Pengambilan sampel dilakukan pada bulan September hingga November 2021 berupa survey observational deskriptif dengan teknik purposive sampling dimana subjek penelitian remaja puteri SMA Muhammadiyah 23 dan SMA Muhammadiyah 11 Jakarta Timur yang berusia 15-19 tahun yang telah memenuhi kriteria inklusi sebanyak 198 responden. Data kuesioner dianalisis menggunakan SPSS IBM 25.0. Hasil penelitian menunjukkan pengetahuan remaja puteri mengenai dismenorea dan obat tradisional dikatakan baik dengan persentase 80,8%, persentase sikap yang positif sebesar 83,8% dan persentase praktik sebesar 45,5%. Analisis korelasi menunjukkan nilai p value 0.01 < 0,05 yang bermakna ada hubungan yang signifikan antara pengetahuan dengan praktik penggunaan obat tradisional dalam mengatasi dismenorea. Dengan demikian, semakin baik persentase tingkat pengetahuan maka persentase tingkat praktiknya juga semakin positif, walaupun beberapa remaja puteri dengan pengetahuan baik  memberikan respon praktik negatif dalam mengatasi dismenorea menggunakan obat tradisional.
Workshop Penentuan Parameter Spesifik dan Non Spesifik Bahan Baku Obat Tradisional pada Mahasiswa Farmasi UHAMKA Melalui PKKM agustin yumita; Ni Putu Ermi Hikmawanti; Fujianti; Novia Delita
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2023)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (419.417 KB) | DOI: 10.31949/jb.v4i1.3722

Abstract

Indonesia's abundant biodiversity provides good opportunities for developing medicines, especially traditional medicines made from plant materials. However, it is necessary to standardize the process to realize quality, safe, and efficacious traditional medicinal preparations. This standardization process is essential. This workshop aims to provide information on the standardization of raw materials for traditional medicines to have the knowledge and ability to standardize medicinal raw materials. At the initial stage, participants will be given a pretest. Furthermore, participants studied specific and non-specific parameters, and at the last stage, the participants were given a posttest. The data obtained from the pretest and posttest will then be processed using Excel and the IBM SPSS Statistics version 25.0 application. From the results of the workshop activities, the average value of the pretest results was 62.5806, smaller than the posttest results of 83.2258. This indicates a significant difference of P < 0.05 between the pretest and posttest. In this workshop, the team provided an understanding to the participants in standardizing the raw materials for traditional medicines. The statistical results also showed a significant effect on the treatment before being given training and after being given training to the workshop participants.
Pharmacognosy, Phytochemical, and Pharmacology of Wijaya Kusuma (Epiphyllum oxypetalum (DC.) Haw.) – An Update Review Chandra Adam Lesmana; Ni Putu Ermi Hikmawanti; Agustin Yumita
Borneo Journal of Pharmacy Vol. 5 No. 2 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i2.3342

Abstract

In Indonesia, Epiphyllum oxypetalum (DC.) Haw. is known as Wijaya Kusuma. The plant is grown for home decorating and used widely as medicine in some areas. This narrative review discusses the pharmacognosy, phytochemical, and pharmacology aspects of E. oxypetalum. The review is limited to original articles and abstracts available in Science Direct, PubMed, and Google Scholar. The keyword used to search the articles was “Epiphyllum oxypetalum”. The plant contains proteins, amino acids, alkaloids, saponins, terpenoids, steroids, flavonoids, tannins, glycosides, and resins. The plant has pharmacological activities such as anti-inflammatory, antimicrobials, antidiabetic, and antioxidant properties. Researchers interested in developing E. oxypetalum as a medicinal plant might use this review as a reference.
Workshop Penentuan Parameter Spesifik dan Non Spesifik Bahan Baku Obat Tradisional pada Mahasiswa Farmasi UHAMKA Melalui PKKM agustin yumita; Ni Putu Ermi Hikmawanti; Fujianti; Novia Delita
BERNAS: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 1 (2023)
Publisher : Universitas Majalengka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31949/jb.v4i1.3722

Abstract

Indonesia's abundant biodiversity provides good opportunities for developing medicines, especially traditional medicines made from plant materials. However, it is necessary to standardize the process to realize quality, safe, and efficacious traditional medicinal preparations. This standardization process is essential. This workshop aims to provide information on the standardization of raw materials for traditional medicines to have the knowledge and ability to standardize medicinal raw materials. At the initial stage, participants will be given a pretest. Furthermore, participants studied specific and non-specific parameters, and at the last stage, the participants were given a posttest. The data obtained from the pretest and posttest will then be processed using Excel and the IBM SPSS Statistics version 25.0 application. From the results of the workshop activities, the average value of the pretest results was 62.5806, smaller than the posttest results of 83.2258. This indicates a significant difference of P < 0.05 between the pretest and posttest. In this workshop, the team provided an understanding to the participants in standardizing the raw materials for traditional medicines. The statistical results also showed a significant effect on the treatment before being given training and after being given training to the workshop participants.