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UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) TERHADAP ISOLAT BAKTERI Escherichia coli JAJANAN CILOK SECARA IN VITRO DENGAN METODE DIFUSI Abima, Fadel; Bahar, Meiskha; Chairani, Aulia
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.317 KB) | DOI: 10.33533/jpm.v11i1.205

Abstract

Diarrhea is still one of the world’s major health problem especially in developing country. Foods and beverages contaminated by microorganism become the risk factor of diarrhea, including Escherichia coli (E. coli). One of the curative effort that can be done is to utilise the secondary metabolite compounds contained in binahong leaf (Anredera cordifolia (Ten.) Steenis). This study used true experimental method. The sample was binahong leaf extract with concentration of 25%, 50, and 75% using diffusion method (Kirby-Bauer) on doublelayered Mueller Hinton Agar (MHA) (base layer and seed layer) in order to measure the growth inhibition zone around the cylinder plate. The amount of population on this study was 24 isolations of E. coli. The repetition of each treatment group was counted by Federer formula. The result analyzed using Kruskal-Wallis test and showed that there was difference on binahong leaf extract effectiveness (p < 0,05), as well as on post hoc analysis using MannWhitney test showed that there was significant difference at concentration of 25%,50%, and 75%. (p < 0,001). This shows that there is a significant differences in the concentration of binahong leaf extract.
HUBUNGAN ANTARA PERILAKU KELUARGA TERHADAP KEJADIAN DEMAM BERDARAH DENGUE DI KELURAHAN PANCORAN MAS Jihaan, Sarah; Chairani, Aulia; Mashoedojo, Mashoedojo
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.865 KB) | DOI: 10.33533/jpm.v11i1.211

Abstract

Dengue Hemorrhagic Fever was a viral endemic disease which has became on of common health problems encountered in Indonesian. The incidence rate of DHF in Kelurahan Pancoran Mas had been become the highest and significant increase from 2010-2015. This research determine the correlation between family health behavior and the incidens of DHF. This is an analytic survey research by cluster random sampling. The subject were all of the people who live in Kelurahan Pancoran Mas with produced a sample is 136 respondents. Data collection use the questioner and analyse by chi square statistic test (P=0,05). From the research result was found that there’s no correlation of family health behavior with dengue incidence with P=0,254 (P>0,05). It can be concluded that the alternative hypothesis in this study (Ha) rejected and the hypothesis (Ho) is accepted where there’s no correlation between of family health behavior with dengue incidence.
Efektivitas Getah Jarak Sebagai Antiseptik terhadap Pertumbuhan Staphylococcus aureus, Escherichia colidan Candida sp. secara In Vitro Chairani, Aulia; Harfiani, Erna
Jurnal Kedokteran Universitas Lampung Vol 2, No 2 (2018): Jk Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jk unila.v2i2.1942

Abstract

Kulit manusia merupakan perlindungan utama terhadap berbagai jenis mikroorganisme yang menyerang imun tubuh. Apabila terjadi kerusakan pada kulit seperti luka, maka terbukalah sistem pertahanan yang kompleks pada kulit. Larutan antiseptik diharapkan dapat membunuh mikroorganisme di sekitar luka agar tidak menyebabkan gangguan lebih lanjut. Salah satu tanaman yang mempunyai zat bioaktif alkaloid, flavonoid, tannin dan saponin yang dapat dipergunakan sebagai antiseptik adalah getah tanaman jarak cina (Jatropha multifida L.).Penelitian ini dilakukan menggunakan metode eksperimental murni, bertujuan untuk mengetahui efektivitas senyawa bioaktif getah jarak cina terhadap bakteri Staphylococcus aureus ( Gram +), dan Escherichia coli (Gram -) dan koloni jamur Candida albicans.Jumlah ulangan tiap kelompok perlakuan menggunakan rumus Federer.Metode penelitian yang digunakan adalah metode difusi agar (Kirby-Bauer) menggunakan medium Mueller Hinton Agar(MHA) untuk bakteri dan Saboround Dextrose Agar (SDA) untuk jamur, dengan mengukur zona hambat di sekitar plat silinder. Analisis data menggunakan uji Non Parametrik Kruskal-Wallis dan Mann Withney. Secara statistik getah jarak cina mempunyai daya antiseptik yang bermakna dengan nilai p=0,000 (p<0,05) pada semua konsentrasi, yaitu 20%,40%,60%,80% dan 100% v/v terutama terhadap Escherichia colidan Staphylococcus aureus, namun tidak berefek antiseptik pada jamur Candida albicans.Hasil penelitian ini menunjukkan bahwa efek antiseptik getah jarak cina berpotensi sama baik dengan betadine yang selanjutnya dapat dimanfaatkan sebagai antiseptik herbal. Kata kunci: Antiseptic, Candida albicans, Escherichia coli, Jatropha multifidaL, Staphylococcus aureus.
HUBUNGAN ADIKSI GAME ONLINE DENGAN KUALITAS TIDUR PADA ANAK DI SMP TERATAI PUTIH GLOBAL BEKASI TAHUN 2020 Widiyani, Khadijah Ratna; Amelia, Fereza; Chairani, Aulia
Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan Vol 5, No 1 (2021): Jurnal Muara Sains, Teknologi, Kedokteran dan Ilmu Kesehatan
Publisher : Universitas Tarumanagara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24912/jmstkik.v5i1.8277

Abstract

Technology advancement that wasn’t dealt with wisely could lead to some problems, one of the exampel is online game addiction, a global sensation that spread through even to Indonesia. There are 4,388 millions of internet user all over the world, with a penetration of 57%, and 30% of them use the internet to play games online, with the prevalention of internet addiction in teenagers higher in Asian countries rather than in America or Europe. One of the symptoms of online game addiction is spanding and wasting too much time in playing online games resulting in lack of sleep and poor sleep quality that could hinder daily function. This study was done to determine the association between online game addiction and sleep quality of children at SMP Teratai Putih Global Bekasi. This is an observational analytic study with cross-sectional design using validated Indonesian Online Game Addiction Questionnaire and Pittsburgh Sleep Quality Index. There are a total of 51 samples in the study, the sampling was done with stratified random sampling. The result of the bivariate analysis in this study is that there is a significant association between online game addiction and sleep quality (p = 0,001, CI = 95%) of children at SMP Teratai Putih Global Bekasi 2020. Only a few research have been conducted on the association between online game addiction and sleep quality, there’s not enough scientific explanation on the phenomenon, so further research is needed. Keywords: online game addiction, children, sleep quality, SMP AbstrakPerkembangan teknologi yang kurang bijak menimbulkan beberapa masalah, salah satu contoh masalah yang muncul adalah adiksi game online yang telah menjadi hiburan global termasuk di Indonesia. Terdapat 4,388 juta pengguna internet di seluruh dunia dengan penetrasi sebesar 57%, dan sebanyak 30% dari jumlah tersebut bermain game secara online, dengan prevalensi adiksi internet pada remaja lebih tinggi di Asia dibandingkan Amerika atau Eropa. Salah satu bentuk gejala dari adiksi game adalah menghabiskan waktu untuk bermain game online yang membuat penderita kekurangan jam tidur sehingga dapat membuat kualitas tidur penderita adiksi menjadi buruk dan menggganggu fungsi kehidupan sehari-hari. Penelitian ini dilakukan untuk menilai hubungan antara adiksi game online tersebut dengan kualitas tidur pada anak di SMP Teratai Putih Global Bekasi. Penelitian ini bersifat analitik observasional dengan desain cross-sectional menggunakan kuesioner Indonesian Online Game Addiction dan Pittsburgh Sleep Quality Index yang telah tervalidasi. Pengambilan sampel sebanyak 51 responden dilakukan secara stratified random sampling. Hasil analisis bivariat penelitian mengatakan adanya hubungan yang signifikan antara adiksi game online dengan kualitas tidur (p = 0,001, CI = 95%) pada anak di SMP Teratai Putih Global Bekasi Tahun 2020. Penelitian tentang hubungan adiksi game online dan kualitas tidur masih sangatlah sedikit, belum terdapat penjelasan ilmiah yang lengkap terkait fenomena ini, sehingga dibutuhkan penelitian lebih lanjut.
HUBUNGAN ANTARA HITUNG JUMLAH CD4 DENGAN KEJADIAN WASTING SYNDROME PADA PASIEN HIV/AIDS DI RSPAD GATOT SOEBROTO PERIODE JANUARI-DESEMBER 2020 Ramadhani Safira Gumarianto; Soroy Lardo; Aulia Chairani
JURNAL KEDOKTERAN DAN KESEHATAN Vol 9, No 2 (2022)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/JKK.V9I2.16975

Abstract

Infeksi HIV masih menjadi ancaman dunia dibidang kesehatan. HIV ialah virus yang menyerang sistem kekebalan tubuh manusia terutama sel-sel imun yang memiliki marker CD4 dipermukaannya. Untuk menilai imunitas pasien HIV/AIDS, diperlukan hitung jumlah CD4. Seseorang dengan jumlah CD4 <200 sel/mm3 dianggap sebagai AIDS, yaitu sekumpulan gejala yang muncul akibat penurunan imunitas tubuh oleh infeksi HIV. Penurunan berat badan merupakan manifestasi yang sangat sering ditemukan pada pasien HIV/AIDS. Tahap akhir dari keadaan penurunan status gizi ini adalah Wasting Syndrome HIV. Tujuan penelitian ini adalah untuk menganalisis hubungan antara hitung jumlah CD4 dengan kejadian wasting syndrome pada pasien HIV/AIDS di RSPAD Gatot Soebroto tahun 2020. Desain penelitian yang digunakan adalah cross sectional menggunakan 53 rekam medik pasien HIV/AIDS di RSPAD Gatot Soebroto. Hasil penelitian ini menunjukkan sebanyak 47,2% pasien HIV/AIDS mengalami wasting syndrome dan 84% diantaranya memiliki CD4 <200 sel/?l. Analisis bivariat dengan uji Chi-Square didapatkan hasil p<0,05 yaitu sebesar 0,033 sehingga dapat disimpulkan bahwa adanya hubungan yang signifikan antara hitung jumlah CD4 dengan kejadian Wasting Syndrome.
GANGGUAN FUNGSI GINJAL PADA IBU HAMIL PREEKLAMPSIA BERAT DENGAN DISLIPIDEMIA DI RSUD KELAS B SERANG Muttia Amalia; Erna Harfiani; Aulia Chairani
Jurnal Kesehatan Reproduksi Vol 11 No 1 (2020): JURNAL KESEHATAN REPRODUKSI VOLUME 11 NOMOR 1 TAHUN 2020
Publisher : Puslitbang Upaya Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/kespro.v11i1.2560

Abstract

Abstract Background: Preeclampsia is one of the leading causes of maternal-fetal morbidity and mortality in developing countries. Dyslipidemia in severely preeclamptic women will develop end-organ damage due to endothelial dysfunction. Objective: The objective of this study was to evaluate the correlation between blood lipid profile and renal function in severely preeclamptic women at RSUD Class B Serang district, January-December 2018. Method: This study was an analytical observational study with a cross-sectional design. Conducted using total sampling technique, 103 pregnant women were included from medical records. Data were analyzed using correlation tests and logistic regression. Result: Correlation analysis indicates that HDL level (<60mg/dL) and LDL level (>160 mg/dL) had a significant impact in the alteration of urea and creatinine level in severe PE. Logistic regression analysis signifies that only decreased level of HDL had a significant partial impact on increasing creatinine levels (p=0,013 OR=1,107). Conclusion: The conclusion of this study was in severe PE women there was an increased level of TG and LDL, with a decreased level of HDL. Dyslipidemia in severe PE women will lead to oxidative stress and endothelial dysfunction, which further will cause alteration in glomerulus structure and disturbance of renal function. Keywords: dyslipidemia, creatinine, severe PE, urea Abstrak Latar Belakang: Preeklampsia (PE) merupakan salah satu penyebab utama kesakitan dan kematian ibu dan bayi di negara berkembang. Dislipidemia pada ibu hamil dengan preeklampsia berat (PEB) akan menyebabkan end-organ damage akibat disfungsi endotel. Tujuan: Tujuan penelitian ini adalah untuk menilai hubungan antara profil lipid darah terhadap gangguan fungsi ginjal pada ibu hamil dengan preeklampsia berat di RSUD Kelas B Serang periode Januari – Desember 2018. Metode: Penelitian ini merupakan penelitian observasi analitik dengan pendekatan cross sectional. Menggunakan teknik total sampling, sebanyak 103 sampel diambil dari data rekam medik. Data dianalisis menggunakan uji korelasi dan regresi logistik. Hasil: Hasil korelasi menunjukkan bahwa kadar HDL yang lebih rendah (<60 mg/dL) dan kadar LDL yang lebih tinggi (>160 mg/dL) memiliki hubungan yang bermakna terhadap peningkatan kadar ureum dan kreatinin pada bumil dengan PEB. Analisis regresi logistik memperlihatkan bahwa hanya kadar HDL yang menurun memiliki hubungan parsial yang signifikan terhadap peningkatan kadar kreatinin (p=0,013 OR=1,107). Kesimpulan: Kesimpulan penelitian ini bahwa telah ditemukan peningkatan kadar trigliserida (TG) dan LDL serta penurunan kadar HDL pada bumil dengan PEB. Dislipidemia pada PEB akan menyebabkan stres oksidasi dan disfungsi endotel yang selanjutnya akan menyebabkan perubahan struktur glomerulus dan perubahan fungsi ginjal Kata kunci: dislipidemia, kreatinin, PEB, ureum
UJI EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN BINAHONG (Anredera cordifolia (Ten.) Steenis) TERHADAP ISOLAT BAKTERI Escherichia coli JAJANAN CILOK SECARA IN VITRO DENGAN METODE DIFUSI Fadel Abima; Meiskha Bahar; Aulia Chairani
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (241.317 KB) | DOI: 10.33533/jpm.v11i1.205

Abstract

Diarrhea is still one of the world’s major health problem especially in developing country. Foods and beverages contaminated by microorganism become the risk factor of diarrhea, including Escherichia coli (E. coli). One of the curative effort that can be done is to utilise the secondary metabolite compounds contained in binahong leaf (Anredera cordifolia (Ten.) Steenis). This study used true experimental method. The sample was binahong leaf extract with concentration of 25%, 50, and 75% using diffusion method (Kirby-Bauer) on doublelayered Mueller Hinton Agar (MHA) (base layer and seed layer) in order to measure the growth inhibition zone around the cylinder plate. The amount of population on this study was 24 isolations of E. coli. The repetition of each treatment group was counted by Federer formula. The result analyzed using Kruskal-Wallis test and showed that there was difference on binahong leaf extract effectiveness (p < 0,05), as well as on post hoc analysis using MannWhitney test showed that there was significant difference at concentration of 25%,50%, and 75%. (p < 0,001). This shows that there is a significant differences in the concentration of binahong leaf extract.
HUBUNGAN ANTARA PERILAKU KELUARGA TERHADAP KEJADIAN DEMAM BERDARAH DENGUE DI KELURAHAN PANCORAN MAS Sarah Jihaan; Aulia Chairani; Mashoedojo Mashoedojo
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 11, No 1 (2017): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (288.865 KB) | DOI: 10.33533/jpm.v11i1.211

Abstract

Dengue Hemorrhagic Fever was a viral endemic disease which has became on of common health problems encountered in Indonesian. The incidence rate of DHF in Kelurahan Pancoran Mas had been become the highest and significant increase from 2010-2015. This research determine the correlation between family health behavior and the incidens of DHF. This is an analytic survey research by cluster random sampling. The subject were all of the people who live in Kelurahan Pancoran Mas with produced a sample is 136 respondents. Data collection use the questioner and analyse by chi square statistic test (P=0,05). From the research result was found that there’s no correlation of family health behavior with dengue incidence with P=0,254 (P>0,05). It can be concluded that the alternative hypothesis in this study (Ha) rejected and the hypothesis (Ho) is accepted where there’s no correlation between of family health behavior with dengue incidence.
Peningkatan Peran Antenatal Care (ANC) dan Pemanfaatan TOGA dalam Kehamilan di Puskesmas Sawangan Depok Erna Harfiani; Muttia Amalia; Aulia Chairani
Jurnal Pengabdian Pada Masyarakat Vol 4 No 4 (2019)
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (724.568 KB) | DOI: 10.30653/002.201944.234

Abstract

ENHANCING OF ANC AND UTILIZATION OF TOGA IN PREGNANCY AT SAWANGAN DEPOK. Women’s and children’s health problems today remain a global challenge and need remedial action. Maternal death is the death of a woman during pregnancy or death within 42 days of termination of pregnancy. Antenatal care (ANC) is an attempt to prevent the causes of morbidity and mortality in pregnant women and children. During pregnancy various physiological changes occur in pregnant women, this certainly has an impact on the psychology and health of pregnant women. TOGA (Family medicinal plants) can be used to help overcome this uncomfortable situation. Plants that can be used by pregnant women include, such as ginger, red spinach, red betel, green betel, tomatoes, and broccoli. There is a possibility of abnormalities such as bleeding, preeclampsia, and infection during pregnancy. Therefore there is a need for monitoring in the form of Antenatal Care during pregnancy and the mother’s understanding of early detection of the risk of abnormalities during pregnancy. This community service is carried out to increase community knowledge around the Sawangan Depok Community Health Center about the importance of ANC and the use of TOGA in pregnant women as well as training in the introduction of several abnormalities and emergencies during pregnancy through counseling with lecture media, pamphlets and pocketbooks on ANC and the use of TOGA. This activity went well and the results can be seen there is an increase in the results of the posttest compared to the pretest, and statistically, there are significant differences.
HUBUNGAN FAKTOR INDIVIDU DAN FAKTOR LINGKUNGAN TERHADAP GEJALA SICK BUILDING SYNDROME PADA STAF TENAGA KE PENDIDIKAN DI FAKULTAS KEDOKTERAN UPN VETERAN JAKARTA TAHUN 2020 Ratna Dwi Krismondani; Aulia Chairani; Nunuk Nugrohowati
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 5 No. 1 (2021): April 2021
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v5i1.1436

Abstract

Background: Sick building syndrome (SBS) are collection of symptoms suffered by workers in offices and other buildings with symptoms such as headaches and respiratory problems. Based on report of the National Health Organization there are estimated 2.2 million deaths due indoor pollution. Where 70-80% of individuals spend their time working indoors. Methods and Samples: The study had used a cross sectional method which aims to determine relationship between individual and environmental factors that influence onset symptoms of SBS. The research data were collected through questionnaires. The sample in this study were 49 educational staff at the Faculty of Medicine UPN Veteran Jakarta. The sampling technique used total sampling. This study used univariate, bivariate, and multivariate analysis. Results: Bivariate analysis: age (p = 0.02), length of service (p = 0.00), psychosocial conditions (p = 0.00) and room ventilation conditions (p = 0.00). While multivariate analysis: age (p = 0.05; OR = 3.524; 95% CI 1.019-14.914), years of service (p = 0.02; OR = 4.168; 95% CI 1.768-16.520), room ventilation (p = 0.03; OR = 7.167; 95% CI 2.705-27.912), and psychosocial conditions (p = 0.012; OR = 8.714; 95% CI 3.072-29.098). Conclusion: Based on the bivariate analysis, there are significant relationship between age, years of service, psychosocial conditions and room ventilation of symptoms SBS. Meanwhile, based on multivariate analysis, psychosocial status is the most influential factor of symtoms SBS