Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Indonesian Pharmacopeia Journal (IPJ) Journal of Pharmacy and Halal Studies (JPHS)
Aliyah Purwanti
Unknown Affiliation
Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
ANTIBACTERIAL ACTIVITY OF ETHANOL EXTRACT OF EDAMAME PEEL AND SEEDS (Glycine max (L.) Merr) AGAINST THE GROWTH OF Staphylococcus aureus Rahmadaniah Affelia; aliyah purwanti; Dhina Susanti
Indonesian Pharmacopeia Journal Vol. 1 No. 2 (2024): July
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v1i2.16

Abstract

Staphylococcus aureus is the cause of acne disease that is resistant to antibiotics in the long term. Edamame is one of the natural ingredients used as an alternative treatment. Edamame seeds have the potential as antibacterial because they contain saponin compounds, in addition edamame peel waste can also be developed as an antibactetrial. The study aims to identify the profile of compound content from edamame peel and seeds extracts, to identify and analyze the antibacterial activity of the extract against Staphylococcus aureus bacteria. Ethanol extract of edamame peel and seeds were obtained from the Ultrasonic Assisted Extraction (UAE) method using 96% ethanol. Each extract was screened for phytochemicals and than made into concentrations of 10%, 20% and 30% to test antibacterial activity using the well diffusion method. Then continued with the One Way Anova test. Ethanol extracts of edamame peel and seeds obtained an average yield of 17,31%±0,57 and 17,10%±0,51. Edamame peel and seeds extracts contain saponins, tannins, steroids, terpenoids, flavonoids dan phenols but edamame seeds do not contain steroid compounds. Edamame peel extract at concentration of 10%, 20% and 30% can inhibit Staphylococcus aureus with an average inhibition zone diameter of 10,13mm±0,54; 12,80mm±0,67 and 14,74mm±0,78 while ethanol extract of edamame seeds produces an average inhibition zone diameter of 9,32mm±0,67; 11,55mm±0,83 and 13,83mm±0,96. The one way Anova test produced a value (Sig.) 0,000 followed by the Post Hoc LSD test showing that there were significant differences between each group. Edamame peel and seeds extracts contain phytochemical compounds such as flavonoids,steroids, phenols, tannins, terpenoidsa and saponins where each compound has a mechanism of inhibiting the growth of Staphylococcus aureus. The antibacterial activity of edamame peel extract is classified as strong at each concentration, while edamame seed extract is classified as strong at concentration of 20% and 30%, than at the concentration of 10% it is classified as moderate.
Formulasi dan Evaluasi Sediaan Hand Body Lotion dari Ekstrak Biji Alpukat (Persea americana Mill.) Angga Dwi Rofiqil Maula; Dina Trianggaluh Fauziah; Aliyah Purwanti; Ayu Tri Agustin
Journal of Pharmacy and Halal Studies Vol. 3 No. 1 (2025): Journal of Pharmacy and Halal Studies (JPHS)
Publisher : Edu Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70608/6hahad10

Abstract

Kulit rentan rusak akibat radikal bebas sinar UV, sehingga membutuhkan antioksidan eksternal. Biji alpukat kaya flavonoid, fenol, vitamin E, tanin, dan asam lemak seperti linoleat, oleat, dan palmitat. Kandungan ini menjaga kelembapan dan kekencangan kulit, cocok digunakan dalam produk seperti hand body lotion. Membuktikan adanya kandungan senyawa dalam biji alpukat dan mendapatkan konsentrasi ekstrak biji alpukat yang menunjukkan mutu fisik yang baik dan hasil sediaan hand body lotion yang dapat diterima dengan baik oleh responden. Aquadest dijadikan pelarut dalam metode dekokta untuk menghasilkan ekstrak biji alpukat yang konsentrasinya mencakup 2%, 5%, dan 8%. Evaluasi sediaan mencakup uji mutu fisik organoleptis, pH, homogenitas, daya lekat, daya sebar, beserta pengujian terhadap panelis yaitu uji hedonik dan iritasi. Data dianalisis melalui aplikasi SPSS versi 25. Hasil uji mutu fisik (organoleptis, pH, homogenitas, daya lekat, beserta daya sebar) memperlihatkan hasil yang memenuhi persyaratan pengujian sediaan yang baik. Pada pengujian terhadap responden mendapatkan hasil penerimaan yang baik dan tidak terjadi reaksi iritasi. Ekstrak biji alpukat kaya akan senyawa flavonoid, tanin, saponin, beserta fenolik. Penelitian memperlihatkan bahwasanya formulasi hand body lotion yang mengandung ekstrak ini memenuhi standar mutu fisik, mencakup uji organoleptis, pH, homogenitas, daya lekat, beserta daya sebar. Pada uji terhadap responden hasil uji hedonik responden lebih menyukai warna sediaan pada formula F1 yaitu 54,5%, sementara aroma 72,7% dan tekstur 63,6% pada formula F2. Pengujian iritasi sediaan hand body lotion ini dapat diterima dengan baik karena tidak menyebabkan iritasi dan aman untuk digunakan.
Co-Authors Adelia Royan Suryani Agustin, Ayu Tri Angga Dwi Rofiqil Maula Dhina Susanti Dina Trianggaluh Fauziah lindawati setyaningrum Lubis Nuril Ubaidilla Rahmadaniah Affelia Tolak Haris Widaddhiya Zahra Anggraini