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Anas Diah Kusumawati
Fakultas Farmasi, Universitas Setia Budi Surakarta
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Medicine & Pharmacology

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Efek Antihiperlipidemia Kombinasi Ektrak Kelopak Bunga Rosella dan Ekstrak Daun Bawang Kucai Dwi Ningsih; Samuel Budi Harsono; Anas Diah Kusumawati; Dinda Nur Mahmudah
Jurnal Farmasi Indonesia Vol 14 No 1 (2017): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (447.518 KB) | DOI: 10.31001/jfi.v14i1.359

Abstract

Research was conducted to determine the antihyperlipidemic activity of the combination of Roselle Petal AndGarlic Chives Leaves ethanol extracton hyperlipidemic rats. To determine the potential effects of a combination of garlic chives leaves and rosella, the test animals were divided into seven treatment groups consisting of a hyperlipidemic control group, rosella group (500 mg / KgBW), garlic chives leaves group (110 mg / KgBW), the combination of Roselle Petal And Garlic Chives Leaves respectively 125 : 82.5 mg / KgBW, 250 : 55 mg / KgBW, and 375 : 27.5 mg / KgBW.Total cholesterol test results obtained percent reduction in total cholesterol rosella group (500 mg / KgBW) amounted to 11.49%, garlic chives leaves group (110 mg / KgBW) amounted to 13.70%, the combination of roselle petal and garlic chives leaves125 : 82.5 mg / KgBW, 250 : 55 mg / KgBW, and 375 : 27.5 mg / KgBW, respectively by 40.60%; 46.80% and 32.80%. The test results obtained percent decrease in triglyceride levels of triglyceride levels rosella group (500 mg / KgBW) amounted to 16.40%, garlic chives leaves group (110 mg / KgBW) amounted to 27.68%, combination of roselle petal and garlic chives leaves 125 :82.5 mg / KgBW, 250 : 55 mg / KgBW, and 375 : 27.5 mg / KgBW, respectively by 18.67%; 45.24% and 15.76%.The combination of roselle petal and garlic chives leaves250 : 55 mg / KgBW more effective to reduce total cholesterol and triglyceride blood of test animals than others.
Co-Authors Dinda Nur Mahmudah Dwi Ningsih Harsono, Samuel Budi