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All Journal Jurnal Farmasi Udayana Jurnal Farmasi Indonesia Jurnal Mandala Pharmacon Indonesia Journal of Pharmaceutical and Health Research Open Access Indonesian Journal of Medical Reviews International Journal of Global Sustainable Research
Harsono, Samuel Budi
Universitas Setia Budi, Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Analisis Penggunaan Antibiotik pada Pasien Rawat Inap Demam Tifoid (ICD A01.0) di Rumah Sakit Umum Daerah Kabupaten Sukoharjo Tahun 2013 dengan Metode ATC/DDD Fatihah Kartikani; Samuel Budi Harsono; Jamilah Sarimanah
Jurnal Farmasi Indonesia Vol 11 No 2 (2014): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1305.904 KB) | DOI: 10.31001/jfi.v11i2.67

Abstract

Typhoid fever is one of healthy problem in Indonesia and other developing countries. Complications and mortality of thyphoid fever decrease with rapid diagnose and appropriate antibiotic treatment. Highly frequency of antibiotic utilization without provisions may result in negative impacts. One quantitative study to analyze drugs utilization is by using the ATC/DDD method. The aim of this study was to determine the quantity of antibiotic utilization in hospitalized patients with typhoid fever in Sukoharjo General Hospital 2013 with ATC/DDD method and compatibility analyze with hospital formularies and hospital medical care standard. This study used a retrospective analysis. The samples used were medical records of hospitalized patients with typhoid fever (≥ 15 years of age) in Sukoharjo General Hospital 2013. Based on the results of this study concluded that the quantity of antibiotic utilization in hospitalized patients with typhoid fever in Sukoharjo General Hospital 2013 calculated based on ATC/DDD method is cefotaxime (36,03%), ampicillin (22,81%), amoxicillin (12,73%), ceftriaxone (10,01%), cefazolin (9,79%),levofloxacin (4,16%), ciprofloxacin (3,95%), and chloramphenicol (0,52%). Compatibility percentage with hospital formularies 100%; hospital medical care standard 10%.
Efek Antihiperlipidemia Kombinasi Ektrak Kelopak Bunga Rosella dan Ekstrak Daun Bawang Kucai Dwi Ningsih; Samuel Budi Harsono; Anas Diah Kusumawati; Dinda Nur Mahmudah
Jurnal Farmasi Indonesia Vol 14 No 1 (2017): Jurnal Farmasi Indonesia
Publisher : Fakultas Farmasi Universitas Setia Budi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (447.518 KB) | DOI: 10.31001/jfi.v14i1.359

Abstract

Research was conducted to determine the antihyperlipidemic activity of the combination of Roselle Petal AndGarlic Chives Leaves ethanol extracton hyperlipidemic rats. To determine the potential effects of a combination of garlic chives leaves and rosella, the test animals were divided into seven treatment groups consisting of a hyperlipidemic control group, rosella group (500 mg / KgBW), garlic chives leaves group (110 mg / KgBW), the combination of Roselle Petal And Garlic Chives Leaves respectively 125 : 82.5 mg / KgBW, 250 : 55 mg / KgBW, and 375 : 27.5 mg / KgBW.Total cholesterol test results obtained percent reduction in total cholesterol rosella group (500 mg / KgBW) amounted to 11.49%, garlic chives leaves group (110 mg / KgBW) amounted to 13.70%, the combination of roselle petal and garlic chives leaves125 : 82.5 mg / KgBW, 250 : 55 mg / KgBW, and 375 : 27.5 mg / KgBW, respectively by 40.60%; 46.80% and 32.80%. The test results obtained percent decrease in triglyceride levels of triglyceride levels rosella group (500 mg / KgBW) amounted to 16.40%, garlic chives leaves group (110 mg / KgBW) amounted to 27.68%, combination of roselle petal and garlic chives leaves 125 :82.5 mg / KgBW, 250 : 55 mg / KgBW, and 375 : 27.5 mg / KgBW, respectively by 18.67%; 45.24% and 15.76%.The combination of roselle petal and garlic chives leaves250 : 55 mg / KgBW more effective to reduce total cholesterol and triglyceride blood of test animals than others.
Hubungan Interaksi Obat Antibiotik dengan Length of Stay Pasien Pneumonia di Rumah Sakit “X” Ponorogo Bima Nur Priambudi; Samuel Budi Harsono; Inaratul Rizkhy Hanifah
Jurnal Mandala Pharmacon Indonesia Vol. 8 No. 2 (2022): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v8i2.191

Abstract

Pneumonia adalah penyakit infeksi pada saluran pernapasan bagian bawah yang merupakan penyebab kematian terbanyak di negara-negara berkembang. Prevalensi penyakit pneumonia di Indonesia tahun 2018 sebanyak 1.017.290 jiwa. Pengobatan pneumonia terdiri dari kombinasi antibiotik dan atau terapi suportif yang apabila digunakan secara bersamaan akan berpotensi terjadinya interaksi obat. Penelitian ini bertujuan untuk mengidentifikasi interaksi obat antibiotik dalam pengobatan pasien pneumonia dan menganalisis hubungannya dengan Length of Stay (LOS). Penelitian menggunakan metode cross-sectional dengan rancangan deskriptif dan data diambil secara retrospektif. Analisis data secara deskriptif menggunakan aplikasi Lexicomp Reference, Medscape Reference dan buku Stokley’s Drug Interaction serta analisis dengan metode Chi-Square untuk mengetahui hubungan antara  kejadian interaksi obat  dengan   LOS. Dari total 73 sampel pada periode Januari- Desember tahun 2021  menunjukkan karakteristik pasien didominasi oleh laki- laki sebesar 43 pasien (58,9%), usia diatas 46 tahun sebanyak 56,2%. Penggunaan antibiotik tunggal terbanyak adalah levofloxacin sebesar 50,8% dan antibiotik kombinasi azithromycin+ levofloxacin sebesar 43,5%. Interaksi obat ditemukan pada 54 pasien dengan mekanisme interaksi farmakodinamik, farmakokinetik dan mekanisme tidak diketahui masing-masing sebesar 72,5%, 18,1%, dan 9,3%. Interaksi berdasarkan tingkat keparahan minor, moderate dan major masing-masing sebesar 5,2%, 74,3%, dan 20,5%. Potensi interaksi obat antibiotik tidak memiliki hubungan dengan lama rawat inap pasien (nilai signifikansi >0,05).
ANALISIS BIAYA DAN KUALITAS HIDUP PASIEN RAWAT JALAN DM TIPE 2 DENGAN TERAPI GLIQUIDONE DIBANDINGKAN GLIMEPIRIDE DI RSUD SURAKARTA TAHUN 2021 Inaratul Rizkhy Hanifah; Ela Dewi Puspita Sari; Samuel Budi Harsono
Jurnal Farmasi Udayana Vol. 11, No. 2, Tahun 2022
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2022.v11.i02.p03

Abstract

Diabetes Mellitus type 2 is a degenerative disease suffered by patients for life. WHO estimates that Indonesia's number of people with diabetes will be around 21.3 million in 2030. Poor blood sugar control in DM patients impacts the decreasing quality of life and increasing health costs. The aim of this study was to analyze the cost of gliquidone therapy compared to glimepiride and the quality of life of outpatients with type 2 DM at the Surakarta Hospital in 2021. The research was conducted using a cross-sectional study design. The sample in this study was obtained through the purposive sampling method with patients who met the inclusion criteria. Cost analysis was carried out by calculating direct medical and non-medical costs, followed by calculating the RUB value to determine which therapy had the most cost-utility. This study was conducted in August-September 2021. Cost data includes total medical costs from hospitals and transportation costs. Quality of life value in this study was measured using the D-QOL questionnaire. The results showed that the RUB value was Rp. 5,389,203; U = 0.749 while glimepiride was Rp. 4,117.949; U = 0.754. The sensitivity test results showed that the cost of non-ADO drugs had the longest range, so it became the most influential factor. More cost-utility compared to gliquidone. Keywords: Oral antidiabetic, CUA, Diabetes Mellitus, Quality of life
Gambaran Pengetahuan Dan Sikap Ibu Dalam Mengobati Diare Menggunakan Tanaman Tradisional di Desa Milangasri Magetan Samuel Budi Harsono; Irfan Zamzani; Liana Djeli Maesaroh
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.2844

Abstract

In Indonesia, traditional medicine is still widely used by the community. Riskesdas data from 2010 to 2018, shows the use of traditional medicines has increased by 44.3%. The use of these traditional medicines to treat various diseases, one of which is diarrhea. Knowledge about the use of traditional medicinal plants to prevent and treat diarrhea has been passed down from generation to generation. The purpose of this study is to provide an overview of the knowledge and attitudes of mothers in treating diarrhea using traditional plants. This research is a non-experimental quantitative research with descriptive data presentation. Sampling was done by non random sampling technique using purposive sampling method. The research instrument used questionnaires and leaflets as educational media. Data analysis used the Kolmogorov-Smirnov test and the Wilcoxon test. The research sample was mothers aged 21-55 years who were in Milangasri Village, Magetan Regency. The results of the study obtained the number of samples of 95 respondents. The level of knowledge in the pre-test in the good category is 37.89% and the post-test in the good category is 91.58%, while the attitude level for the pre-test in the good category is 51.58% and the post-test in the good category is 89.47%. Kolmogorov test obtained results 0.000 < 0.05 which means the data is not normally distributed and Wilcoxon test results obtained 0.00 < 0.05 which indicates the influence of education on the level of knowledge and attitudes of respondents.
Problems Treatment Type II Diabetes Mellitus Patients with PCNE 9.1 and Correlation to Therapy Outcomes Okky Intan Mawarni; Rina Herowati; Samuel Budi Harsono
International Journal of Global Sustainable Research Vol. 1 No. 3 (2023): November 2023
Publisher : MultiTech Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59890/ijgsr.v1i3.805

Abstract

Drug-Related Problems in T2DM patients based on patient therapy patterns with or without comorbidities. DRP analysis is based on PCNE 9.1 guidelines analysing the domains causing problems in treatment, then bivariate data analysis (chi-square) to test the relationship between results and DRP type and continued with a multivariate test to see the connection between results and DRP type. The research results were three related variables related to DRPs and LOS, 15 cases of errors in drug selection, and eight instances of errors of treatment duration due to the absence of initiation of maintenance doses. Dose selection errors occurred in year 16, caused by an amount too low. It is recommended to research analysis prospectively so that the status of DRPs can be determined.
Evaluation of Drug Management and Improvement Strategies Using the Hanlon Method in the Pharmacy Installation of Dr. Moewardi General Hospital, Surakarta, Indonesia Imelia, Lanny; RA.Oetari; Samuel Budi Harsono
Open Access Indonesian Journal of Medical Reviews Vol. 3 No. 6 (2023): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v3i6.446

Abstract

A hospital pharmacy (FRS) is a unit in a hospital that carries out health efforts by providing quality health services. Medication management in FRS is an important management aspect in achieving service quality. Therefore, IFRS must be managed effectively and efficiently. Inefficiency in use can have a negative impact on hospitals both medically and economically. The aim of this study was to evaluate drug management, including selection, procurement, distribution, and use, based on the 2020 National Formulary standards and improvement strategies using the Hanlon method at the pharmacy installation of Dr. Moewardi General Hospital in 2020. This research is a type of descriptive research with retrospective and concurrent data collection. Data was taken from retrospective data in 2020 and data at the time the research was conducted. Research materials include primary data obtained from observation of research data in the form of document selection, procurement, distribution, and use of medicine in the IFRS Dr. Moewardi General Hospital. Secondary data was obtained from interviews with the head of the pharmacy installation at Dr. Moewardi General Hospital Surakarta, the head of planning, and the head of ULP (procurement services unit). The results of the research show that 1) Medication management in the pharmacy installation at Dr. Moewardi General Hospital Surakarta is not yet efficient at this stage of selection. It is known that the availability of existing medicines does not comply with FORNAS standards in 2020. then, in stage procurement, there is 1 out of 5 indicators that meet the standard; in stage distribution, 5 indicators were obtained, or all of them were not standard, and in staged use, it was found that 1 of the 5 indicators met the standard. 2) The improvement strategy uses the Hanlon method in drug management, namely prioritizing problem repairs sequentially, starting from the percentage of conformity with the number of drug items available with FORNAS to the number of drug items per prescription sheet.
Evaluation of Vaccine Stock Management at the Karanganyar Regency Health Service Indonesia Kurniawan, Andre; Jason Merari Peranginangin; Samuel Budi Harsono
Open Access Indonesian Journal of Medical Reviews Vol. 4 No. 1 (2024): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v4i1.506

Abstract

Vaccines are very susceptible to damage, so vaccine management requires special handling, this is done to maintain vaccine quality. The aim of this research is to find out the description and evaluate suitability vaccine management at the Karanganyar Regency Health Service (DKK) in 2022 based on Minister of Health Regulation No. 12 of 2017. This research is a qualitative descriptive non-experimental research. These research methods cross sectional by using approach, observation or data collection. The sampling technique uses accidental sampling by reviewing and evaluating vaccine management, which includes planning, procurement, receipt, storage, and distribution at the Karanganyar Health Service. The method used for data collection uses checklist suitability and in-depth interviews with the Head of Installation and pharmacy officers. Vaccine planning is adjusted to the usage index and needs in the previous year using a combined method system top to bottom and bottom up. Vaccine procurement is centralized at the Provincial Health Service, where requests are made by method bottom up. Receiving the vaccine is not immediate drop from the center/province, but the Karanganyar DKK takes the needed vaccines to the Provincial Health Service using the provisions for good drug distribution methods. Vaccine storage and distribution at DKK Karanganyar is in accordance with Minister of Health Regulation number 12 of 2017 and also in accordance with vaccine management guidelines from the Ministry of Health in 2021. Vaccines at DKK Karanganyar are in accordance with Minister of Health Regulation number 12 of 2017 and also in accordance with vaccine management guidelines from the Ministry of Health in 2021, both in planning, procurement, receipt, storage and distribution.
Co-Authors Anas Diah Kusumawati Andre Kurniawan Bima Nur Priambudi Dinda Nur Mahmudah Dwi Ningsih Ela Dewi Puspita Sari Fatihah Kartikani Imelia, Lanny Inaratul Rizkhy Hanifah Jamilah Sarimanah Jason Merari Peranginangin Liana Djeli Maesaroh Okky Intan Mawarni RA.Oetari Zamzani, Irfan