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All Journal Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences
Ayu Mayangsari
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Religion Arts Humanities Economics, Econometrics & Finance Social Sciences

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The Effectiveness of Topical Tea Tree Oil (Terpinen-4-Ol) in Human Demodicosis: A Literature Review Ayu Mayangsari; Ratih Pramuningtyas; Aulia Nissa Rizky Hariyono; Zhela Fatin Fatiha; Tia Mella Citra
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2312

Abstract

Demodecosis is a skin disorder caused by parasites with the demodicosis type. The primary cause of this condition in humans is two kinds of Demodex mites, D.folliculorum and D.brevis. Demodicosis are usually treated with TTO, but the effectiveness is not well documented. To evaluate the effects of topical Tea Tree Oil on demodicosis infestation in people. We use the following string in Google Scholar; PubMed; Science Directs with keywords (“Demodicosis”iORi“demodex”iOR"D.folliculorum"iORii"D.Brevis) ANDi (TTOiORiT4OiOR "tea tree oil"). The articles compatible with the restriction criteria then screened using the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) method.  The quality of the articles is tested using GRADE method. A total of 4 of 1949 articles recorded according to the inclusion criteria, all three articles were randomized clinical trials. 351 patients were treated with topical Tea Tree Oil (TTO) scrub with eyelash shampoo, the most common ocular symtomps is ocular dryness. The treatment is provided on a scale 18 to 35 years of age, topical TTO scrub with consentrated persentation 5-50% with eyelash shampoo was at twice-daily treament for 4 weeks. No serious side effect. Topical administration of Tea Tree Oil has shown a reduction in human demodicosis.
Propranolol Oral Treatment for Infantile Hemangioma : A Systematic Review Aulia Nissa Rizky Hariyono; Ratih Pramuningtyas; Zhela Fatin Fatiha; Ayu Mayangsari; Tia Mella Citra
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2308

Abstract

The most common benign tumor in infants is infantile hemangioma. Propranolol is often used as a treatment in patients with IHs. Efficacy and side effects of oral propranolol are considered important to be systematically reviewed in the management of IH. We searched Google Scholar, Pubmed, Garuda, and Science Direct. The articles matched with the restriction criteria then screened using the PRISMA method. The quality of the articles is tested using GRADE method. Total of 4 of 6289 articles recorded at the identification stage according to the inclusion criteria, 452 patients were treated with oral propranolol. All four articles were randomized clinical trials. Treatment is given at 0.3 month to 15 years of age, the dose given is 1-3 mg/kg/day. The primary end point was performed at week 24. The most common side effect is sleeping disorder (n=85). Serious side effects (Hypotension, bronchospasm, bradycardia, hypoglycemia) were managed by decreasing doses or temporary/permanent discontinuation of oral propranolol. Oral propranolol can be used with good efficacy. Monitor before and during treatment is assessed appropriately to reduce side effect.
Co-Authors Afif Bintoro Aulia Nissa Rizky Hariyono Indriyanto . Ratih Pramuningtyas Surnayanti . Tia Mella Citra Zhela Fatin Fatiha