Article Per Year (5 Year)
p-Index From 2020 - 2025
0.817
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Indonesia Pharma Xplore : Jurnal Sains dan Ilmu Farmasi ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Kesehatan Bakti Tunas Husada
Lilis Tuslinah
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

Published : 7 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : ad-Dawaa : Journal of Pharmaceutical Sciences

 1 
Analysis of Body Weight Profile and Toxic Symptoms of White Rats on Giving Ethanol Fraction of Rambutan Peels (Nephelium lappaceum L) Anisa Pebiansyah; Lilis Tuslinah; Ade Yeni Aprilia
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol. 6 No. 1 (2023)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v6i1.37708

Abstract

Introdiction: Rambutan peel (Nephelium lappaceum L) contains antioxidant compounds like flavonoids such as anthocyanins. The high antioxidant activity causes the high utilization of rambutan peel for treatment, but its side effects on the body are unknown. Aims: This study aimed to analyze the effect of giving rambutan rind ethanol fraction on body weight and toxic symptoms in white rats. Methods: The test was carried out using the OECD 425 method in which there were three treatment groups, each consisting of 5 test animals that were given the preparation orally. Treatment 1 was only given 1% CMC Na for 14 days; treatment 2 was given the ethanol fraction of rambutan peel 400 mg/200 g BW which was observed every 30 minutes for 4 hours, then up to 48 hours, then every day for up to 14 days. If there is none, it is continued with treatment 3, which is given the ethanol fraction of rambutan peel 1000 mg/200 g BW for 14 days. Symptoms of acute animal toxicity were observed for 14 days in that treatment. Result: The results showed that the ethanol fraction of rambutan peel doses of 400 mg/200 g BW and 1000 mg/200 g BW had a significant effect (p=0.017) in increasing the body weight profile of white rats, and there were no signs of acute toxicity in each treatment group. Conclusion: The dose of the ethanol fraction of rambutan peel 400 mg/200 g BW is the best, with an increased body weight of 25.17%.
Co-Authors Ade Yeni Aprilia Anisa Pebiansyah Diana Sri Zustika Gatut Ari Wardani Gunarti, Neni Sri Penti Winarti Saeful Amin Widdy Erlinasari