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ANALISIS TINGKAT KEPATUHAN PASIEN TBC RAWAT JALAN TERHADAP PENGGUNAAN OBAT ANTI TUBERKULOSIS DI PUSKESMAS SINDAR RAYA Supartiningsih Supartiningsih; RD.Siti Riski Ainun
Jurnal Pengabdian Masyarakat Multidisiplin Vol 4 No 3 (2021): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jpm.v4i3.1839

Abstract

ABSTRACT The incidence of pulmonary tuberculosis is still very high and difficult to reduce due to the lack of compliance in taking anti-tuberculosis drugs. The lack of knowledge and family support are some of the factors that affect the level of patients’ compliancein taking anti-tuberculosis drugs. The purpose of this study is to have an overview of patients’ compliance and to see how the relationship between knowledge and family support can affect TB outpatients in taking anti- tuberculosis drugs at the Sindar Raya Community Health Center. This type of research is quantitative using a cross-sectional approach to 20 respondents who do outpatient treatment at the Sindar Raya Community Center. The sampling technique uses the total sampling technique. The data collecting is done by giving questionnaires to each respondent. The data analysis uses univariate analysis and Chi Square test on bivariate analysis. The results of the univariate research showed that there were 10 respondents (50.0%) with a good level of knowledge,8 respondents (40.0%) with moderate level knowledge, and2 respondents (10.0%) with the lack of knowledge. Good family support showed as many as 9 respondents (45.0%),5 respondents (25.0%) with moderate support, and6 respondents (30.0%) with lack of support. As many as 15 respondents (75.0%) showed a good level of compliance while 5 respondents (25.0%) showed the lack of compliance level. Based on bivariate analysis with the chi square test, there was a significant relationship between knowledge and compliance to taking anti-tuberculosis drugs (P value = 0.036), and there was also a significant relationship between family support and compliance to taking anti-tuberculosis drugs (P value = 0.017).
Pentingnya Bahan Kimia Sebagai Antibakteri Candrika Candrika; Natanael Priltius; Supartiningsih Supartiningsih; Gabriela Y Br Saragih; Irdanotalia Laia; Masna Elfina; Rani Renata Tondang; Winda Rahman Lase; Zakkan Zakia
Jurnal Intelek Dan Cendikiawan Nusantara Vol. 3 No. 01 (2026): Februari - Maret 2026
Publisher : PT. Intelek Cendikiawan Nusantara

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Abstract

Bakteri merupakan mikroorganisme yang dapat memberikan dampak negatif terhadap kesehatan manusia, terutama pada lingkungan sekolah yang memiliki tingkat interaksi tinggi. Salah satu upaya pencegahan penyebaran bakteri adalah dengan penggunaan bahan kimia sebagai antibakteri. Penelitian ini bertujuan untuk meningkatkan pengetahuan dan pemahaman siswa/i SMP Rahmat Islamiyah mengenai peran dan pentingnya bahan kimia sebagai antibakteri dalam kehidupan sehari-hari. Metode yang digunakan adalah pemberian edukasi melalui penyuluhan dan diskusi interaktif kepada siswa/i. Kegiatan ini dilaksanakan pada tanggal 28 Januari 2026 di SMP Rahmat Islamiyah. Hasil penelitian ini menunjukkan adanya peningkatan pemahaman siswa mengenai jenis bahan kimia antibakteri, cara kerja, serta penggunaan yang aman dan tepat. Edukasi ini diharapkan dapat membentuk perilaku hidup bersih dan sehat sejak dini. Kesimpulan penelitian ini adalah edukasi tentang pentingnya bahan kimia sebagai antibakteri dapat meningkatkan pemahaman siswa SMP mengenai pencegahan penyebaran bakteri. Kegiatan ini membantu menumbuhkan kesadaran siswa untuk menerapkan perilaku hidup bersih dan sehat dalam kehidupan sehari-hari.
PROFIL KADAR LIPID TRIGLISERIDA PADA TIKUS PUTIH JANTAN SETELAH PEMBERIAN EKSTRAK ETANOL DAUN SENGGANI (Melastoma malabathricum L.) Supartiningsih Supartiningsih; Manuppak Irianto Tampubolon; Susi Elpida Wati
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 10 No. 1 (2026): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v10i1.2465

Abstract

Dyslipidemia was characterized by abnormal blood lipid levels, including elevated total cholesterol, triglycerides, and LDL, accompanied by decreased HDL, and could contribute to cardiovascular diseases. Statins were commonly used to manage dyslipidemia but could cause adverse effects. Senggani leaves (Melastoma malabathricum L.) contained flavonoids with potential antioxidant activity that could inhibit LDL oxidation. This study aimed to determine the effect of ethanolic extract of senggani leaves (Melastoma malabathricum L.) on triglyceride levels in male white rats induced by a high-fat diet. This laboratory experimental study used a pre-test and post-test control group design. The subjects were male white rats induced with a high-fat diet and divided into six groups: normal control, negative control (1% Na-CMC), positive control (simvastatin), and ethanolic extract groups receiving doses of 100, 200, and 400 mg/kg body weight. Lipid levels were measured on days 7, 14, and 28. Data were analyzed using paired t-test and one-way ANOVA, followed by the LSD post-hoc test. One-way ANOVA showed a significant difference in HDL levels among groups (p = 0.000; p< 0.05). The LSD test showed significant differences between all extract dosage groups and the negative control (p< 0.05). Thus, the ethanolic extractpof senggani leaves affected HDL cholesterol levels in male white rats at doses of 100, 200, and 400 mg/kg body weight.