Oea Khairsyaf
Universitas Andalas

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Correlation of qSOFA and NLR to Procalcitonin Levels for Predicting Outcome of Pneumonia Sepsis Patients at RSUP dr. M. Djamil Padang Ibnu Arief Dafitri; Oea Khairsyaf; Irvan Medison; Yessy S. Sabri
Jurnal Respirologi Indonesia Vol 40, No 3 (2020)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

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Backgrounds: Sepsis is a common complication that occurs due to infection and can increase morbidity and mortality in patients. Several methods are applied to evaluate the prognosis of sepsis, such as quick Sequential Organ Failure Assesment (qSOFA) score, Neutrophil Lymphocyte Ratio (NLR) and procalcitonin. This study aimed to determine correlation of qSOFA and NLR on procalcitonin levels to predict the outcome of pneumonia sepsis patients in the pulmonary ward of RSUP dr. M. Djamil Padang. Methods: This was a cross sectional study of pneumonia sepsis patients in the pulmonary ward of the RSUP dr. M. Djamil Padang during September 2019 - February 2020. The qSOFA score was assessed based on physical examination, while both NLR and procalcitonin were measured from blood tests. Results: There was a significant relationship between qSOFA score and procalcitonin levels (r=0.409; P=0.006). There were no significant correlation between NLR and procalcitonin levels (r=0.232; P=0.134). There was a significant correlation between qSOFA score and patient outcome (P=0.036), there was no significant relationships between procalcitonin levels and patient outcomes (P=0.249), and there were no significant correlation between NLR and patient outcomes (P=0.157). Conclusions: qSOFA score was more considered method to evaluate the outcome of pneumonia sepsis patients. (J Respir Indo. 2020; 40(3): 173-81)
Hyperbaric Oxygen: A Critical Treatment for Carbon Monoxide Intoxication Ricky Permata Irzal; Deddy Herman; Oea Khairsyaf
Jurnal Kesehatan Vol. 16 No. 2 (2025): Jurnal Kesehatan Volume 16 Nomor 2 Tahun 2025
Publisher : LPPM Universitas Prima Nusantara Bukittinggi

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Hyperbaric Oxygen Therapy (HBOT) is a medical intervention that involves administering pure oxygen at high pressure for various conditions like decompression sickness, severe anemia and including carbon monoxide (CO) poisoning. This literature review aims to evaluate the effectiveness of HBOT in reducing neurocognitive symptoms caused by CO poisoning, as well as to review the mechanisms, indications, contraindications, and application of Hyperbaric Oxygen Therapy in Carbon Monoxide Poisoning. The review findings indicate that HBOT significantly enhances tissue oxygenation and accelerates the healing process, which can reduce the risk of neurocognitive damage. Hyperbaric Oxygen Therapy has also been found to modulate inflammatory responses, which play a crucial role in the recovery of patients with CO poisoning. However, some studies show variations in the long-term effectiveness of HBOT on neurocognitive symptoms, highlighting the need for further research. This literature review concludes that HBOT offers significant benefits in the treatment of CO poisoning; however, further research is needed to optimize clinical use and ensure its long-term effectiveness.