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Devi Novia
Sekolah Tinggi Kesehatan Al-Fatah Bengkulu
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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FORMULASI SEDIAAN SIRUP SARI BUAH SENGGANI (Melastoma malabathricum L.) Tri Yanuarto; Devi Novia; Septi Putri Lestari
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.914

Abstract

Senggani fruit (Melastoma malabathricum L.) is one of the wild plants whose leaves are usually used by the community as a medicine for wounds and cancer sores. Senggani fruit contains high anthocyanins and antioxidants, which are very good for preventing cancer in the body. The purpose of this research is to make syrup of Senggani fruit juice. The formulation of Senggani fruit juice syrup was made by heating method at 54°C with various concentrations of F0, F1 (5%), F2 (6%) and F3 (8%). Then, the physical properties were tested, namely organoleptic, viscosity test, pH test, homogenity test, hedonic test and descriptive test. From testing the physical properties of the syrup formulation of Senggani fruit, it was found that the organoleptic test of F2 and F3 showed a change in consistency; for the pH test results the four formulas ranged from 3.98 to 7.07; the homogeneity test on F2 and F3 was not homogeneous, there were black grains at the 3rd week; then the viscosity test of syrup preparations F2 and F3 obtained an average result of 30 - 51.33 cPs; as well as hedonic and descriptive tests with the criteria of somewhat like - like the most preferred is F3.
Uji Aktivitas Sediaan Obat Kumur Ekstrak Daun Bidara Arab (Ziziphus spina-cristi L) Terhadap Pertumbuhan Bakteri Streptococcus mutans Devi Novia
Jurnal Ilmiah Pharmacy Vol 8, No 2 (2021)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v8i2.345

Abstract

Indonesia merupakan Negara yang banyak memiliki tanaman yang dapat digunakan sebagai obat tradisional, salah satunya daun bidara arab ( Ziziphus spina-chirsti L), daun bidara arab diketahui memiliki aktivitas antibakteri. bakteriStreptococcus mutans yang merupakan penyebab timbulnya plak dan karies gigi. dengan menggunakan obat kumur antiseptik dapat mencegah timbulnya plak dan karies gigi. Uji daya hambat antibakteri dilakukan dengan metode difusi agar. Konsentrasi obat kumur yang digunakan adalah 1%, 3%, 5%, kontrol (+) obat kumur yang beredar dipasaran (total care) dan kontrol (-) kemudian diinkubasi selama 24 jam pada suhu 37º C. Zona bening diukur. Hasil yang diperoleh bahwa obat kumur ekstrak daun bidara arab ( Ziziphus spina-chirsti L) mampu menghambat pertumbuhan bakteri Streptococcus mutans. kosentarasi yang paling bagus adalah kosentrasi 5% yaitu 13,54 mm. Dan kontrol (+) dapat menghambat pertumbuhan bakteri Streptococcus mutans dengan nilai 15,88 mm dan termasuk katagori kuat. Kata Kunci :Daun bidara arab (Ziziphus spina-chirsti L), obat kumur , Streptococcus mutans
EFEKTIVITAS ANALGETIK KRIM TIPE M/A EKSTRAK ETANOL DAUN RANDU (Ceibapentandra (L) Gaertn) PADA HEWAN UJI MENCIT JANTAN Setya Enti Rikomah; Devi Novia; Muhammad Fadhly
Denta Journal Kedokteran Gigi Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.63

Abstract

Randu plant leaves (Ceiba pentandra (L) Gaertn) are commonly used in traditional medicine, one of which is an analgesic with secondary metabolites which are thought to be analgesics, namely flavonoids. The purpose of this study was to determine the analgesic effectiveness of the ethanol extract cream of randu leaves (Ceiba pentandra (L) Gaertn) in white male mice (Mus musculus). The research on the analgesic effectiveness of the ethanol extract cream of randum leaves used the hot plate method and used male white mice as the experimental animal media. The soles of the hind legs of the mice were heated over hot plated with a temperature of 550C then the test animals were given the treatment which was divided into 5 treatment groups, namely positive control (Conterpain cream), negative control (F0), F1 (10%), F2 (15%), F3 (20%) and 1 normal group. The response of mice was calculated every 30 minutes in 120 minutes. The data obtained were analyzed using the one-way ANOVA statistical test followed by the Duncan test with a confidence level of 99%. The results of the one-way ANOVA test showed that there were significant differences between treatment groups (0.00 <0.05). The results of the Duncan test showed that the group that provided the best analgesic effectiveness was F2 (15%) but not better than Positive Control.
EFEKTIVITAS ANALGETIK KRIM TIPE M/A EKSTRAK ETANOL DAUN RANDU (Ceibapentandra (L) Gaertn) PADA HEWAN UJI MENCIT JANTAN Setya Enti Rikomah; Devi Novia; Muhammad Fadhly
Oceana Biomedicina Journal Vol 5 No 1 (2022): Oceana Biomedicina Journal Volume 5 Issue (No) 1
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v5i1.63

Abstract

Randu plant leaves (Ceiba pentandra (L) Gaertn) are commonly used in traditional medicine, one of which is an analgesic with secondary metabolites which are thought to be analgesics, namely flavonoids. The purpose of this study was to determine the analgesic effectiveness of the ethanol extract cream of randu leaves (Ceiba pentandra (L) Gaertn) in white male mice (Mus musculus). The research on the analgesic effectiveness of the ethanol extract cream of randum leaves used the hot plate method and used male white mice as the experimental animal media. The soles of the hind legs of the mice were heated over hot plated with a temperature of 550C then the test animals were given the treatment which was divided into 5 treatment groups, namely positive control (Conterpain cream), negative control (F0), F1 (10%), F2 (15%), F3 (20%) and 1 normal group. The response of mice was calculated every 30 minutes in 120 minutes. The data obtained were analyzed using the one-way ANOVA statistical test followed by the Duncan test with a confidence level of 99%. The results of the one-way ANOVA test showed that there were significant differences between treatment groups (0.00 <0.05). The results of the Duncan test showed that the group that provided the best analgesic effectiveness was F2 (15%) but not better than Positive Control.
FORMULASI SEDIAAN SIRUP SARI BUAH SENGGANI (Melastoma malabathricum L.) Tri Yanuarto; Devi Novia; Septi Putri Lestari
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.914

Abstract

Senggani fruit (Melastoma malabathricum L.) is one of the wild plants whose leaves are usually used by the community as a medicine for wounds and cancer sores. Senggani fruit contains high anthocyanins and antioxidants, which are very good for preventing cancer in the body. The purpose of this research is to make syrup of Senggani fruit juice. The formulation of Senggani fruit juice syrup was made by heating method at 54°C with various concentrations of F0, F1 (5%), F2 (6%) and F3 (8%). Then, the physical properties were tested, namely organoleptic, viscosity test, pH test, homogenity test, hedonic test and descriptive test. From testing the physical properties of the syrup formulation of Senggani fruit, it was found that the organoleptic test of F2 and F3 showed a change in consistency; for the pH test results the four formulas ranged from 3.98 to 7.07; the homogeneity test on F2 and F3 was not homogeneous, there were black grains at the 3rd week; then the viscosity test of syrup preparations F2 and F3 obtained an average result of 30 - 51.33 cPs; as well as hedonic and descriptive tests with the criteria of somewhat like - like the most preferred is F3.
PENYULUHAN KESEHATAN GIGI DAN MULUT DAN GERAKAN SIKAT GIGI YANG BAIK DAN BENAR DI SD NEGERI 17 KOTA BENGKULU Syauqul Jannah; Devi Novia
SEMAR : Jurnal Sosial dan Pengabdian Masyarakat Vol. 4 No. 2 (2026): Semar : Jurnal Sosial dan Pengabdian Masyarakat
Publisher : CV. Kalimasada Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59966/semar.v4i2.2537

Abstract

Dental health education for children is one of the efforts to instill an understanding in children that dental health is important. There are so many choices of health education methods to support good communication. The most commonly used conventional counseling method is lectures, which is a way of teaching through the presentation of facts and ideas orally, with or without media. Another educational method that is also effective and interesting for children is the storytelling method. This study was conducted to determine differences in the level of knowledge of dental and oral health after counseling using conventional methods and storytelling activities in grade 1 students at SD 17 Bengkulu. The total population of this study was 64 children. The results of the counseling conducted at SD 17 Bengkulu showed that grade 1 children still did not have sufficient knowledge about caring for their teeth and mouth, because children at SD 17 Bengkulu rarely received examinations and counseling about dental and oral health from the local health center.
FORMULASI DAN UJIANTIINFLAMASI SALEP EKSTRAK RESIN JERNANG (Daemonorops Draco (Wild)) Blume PADA MENCIT JANTAN PUTIH(Wistar). Feliza Mayasari; Devi Novia; Tri Yanuarto
Jurnal Komunitas Farmasi Nasional Vol. 5 No. 02 (2025): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Jernang sap (Daemonorops draco (Willd.) Blume) is the exudate of the jernang rattan fruit which has been traditionally used as a traditional medicine. The active compounds contained in it include flavonoids, saponins, terpenoids, alkaloids, and phenolics, which are known to have potential as anti-inflammatory agents. This study aims to design a topical preparation in the form of an ointment from jernang sap extract and to test its physical quality and anti-inflammatory effects in vivo. The extraction process was carried out using a maceration technique using 96% ethanol, then the extract obtained was formulated into three variations of ointment with different concentrations (F1: 1%, F2: 2%, F3: 3%), using a base of vaseline flavum, lanolin, and propyl paraben as a preservative. Testing the physical quality of the ointment included organoleptic examination, homogeneity, pH value, spreadability, and viscosity. Anti-inflammatory activity was tested using male mice (Mus musculus) induced with 1% carrageenan on the paws, and the edema volume was measured using a plethysmometer. The results showed that an ointment made from jernang extract could be prepared with stable physical properties during storage. ANOVA analysis and further testing showed that formulas with higher concentrations (F2 and F3) provided a significant inflammation-inhibiting effect, nearly comparable to the positive control, a 2.5% hydrocortisone ointment. Thus, jernang extract has potential as a natural ingredient for topical anti-inflammatory ointments.
Identifikasi Flavonoid Ekstrak Fraksi Etil Asetat Daun Asam Jawa terhadap Streptococcus mutans Intan Harlesi; Devi Novia; Tri Yanuarto; Luky Dharmayanti
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 9 No. 3 (2026): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v9i3.4583

Abstract

Bakteri Streptococcus mutans diketahui memiliki peranan dalam proses terjadinya karies gigi, sehingga diperlukan alternatif antibakteri yang berasal dari bahan alam. Penelitian ini dilakukan untuk mengetahui keberadaan senyawa flavonoid dalam ekstrak fraksi etil asetat daun asam jawa (Tamarindus indica L.), menganalisis kandungan flavonoid total, serta menguji aktivitas antibakterinya terhadap Streptococcus mutans. Daun asam jawa diekstraksi melalui proses maserasi dengan etanol 96%, kemudian dilanjutkan dengan fraksinasi menggunakan etil asetat. Keberadaan flavonoid dikonfirmasi melalui skrining fitokimia dan Kromatografi Lapis Tipis (KLT), sedangkan kandungan flavonoid total dianalisis menggunakan spektrofotometer UV-Vis dengan kuarsetin sebagai standar pada panjang gelombang 432 nm. Aktivitas antibakteri diuji menggunakan teknik difusi cakram dengan konsentrasi 25%, 50%, dan 75%, menggunakan chlorhexidine gluconate 0,2% sebagai kontrol positif dan DMSO 10% sebagai kontrol negatif. Hasil penelitian menunjukkan bahwa ekstrak fraksi etil asetat positif mengandung flavonoid dengan kadar flavonoid total sebesar 4,091%. Nilai Rf sampel sebesar 0,94 dan Rf kuarsetin sebesar 0,88 menunjukkan selisih nilai Rf sebesar 0,06. Rerata diameter zona hambat yang diperoleh pada konsentrasi 25%, 50%, dan 75% masing-masing sebesar 11,74; 16,53; dan 21,48 mm, sedangkan kontrol positif menghasilkan diameter hambat sebesar 11,27 mm dan kontrol negatif tidak membentuk zona hambat. Analisis One-Way ANOVA memperlihatkan adanya perbedaan yang signifikan antarperlakuan (p<0,05), dengan konsentrasi 75% menghasilkan daya hambat paling tinggi. Dengan demikian, ekstrak fraksi etil asetat daun asam jawa positif mengandung flavonoid dan memiliki aktivitas antibakteri terhadap Streptococcus mutans, dengan konsentrasi 75% sebagai perlakuan yang memberikan efektivitas terbaik
Co-Authors dharmayanti, luky dharmayanti Feliza Mayasari Intan Harlesi Muhammad Fadhly Septi Putri Lestari Setya Enti Rikomah Syauqul Jannah Tri Yanuarto