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All Journal Jurnal Ilmiah Manusia dan Kesehatan Jurnal Insan Farmasi Indonesia Jurnal Komunitas Farmasi Nasional
Tri Yanuarto
Sekolah Tinggi Kesehatan Al-Fatah Bengkulu
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Physics Public Health

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FORMULASI SEDIAAN SIRUP SARI BUAH SENGGANI (Melastoma malabathricum L.) Tri Yanuarto; Devi Novia; Septi Putri Lestari
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.914

Abstract

Senggani fruit (Melastoma malabathricum L.) is one of the wild plants whose leaves are usually used by the community as a medicine for wounds and cancer sores. Senggani fruit contains high anthocyanins and antioxidants, which are very good for preventing cancer in the body. The purpose of this research is to make syrup of Senggani fruit juice. The formulation of Senggani fruit juice syrup was made by heating method at 54°C with various concentrations of F0, F1 (5%), F2 (6%) and F3 (8%). Then, the physical properties were tested, namely organoleptic, viscosity test, pH test, homogenity test, hedonic test and descriptive test. From testing the physical properties of the syrup formulation of Senggani fruit, it was found that the organoleptic test of F2 and F3 showed a change in consistency; for the pH test results the four formulas ranged from 3.98 to 7.07; the homogeneity test on F2 and F3 was not homogeneous, there were black grains at the 3rd week; then the viscosity test of syrup preparations F2 and F3 obtained an average result of 30 - 51.33 cPs; as well as hedonic and descriptive tests with the criteria of somewhat like - like the most preferred is F3.
FORMULASI SEDIAAN SIRUP SARI BUAH SENGGANI (Melastoma malabathricum L.) Tri Yanuarto; Devi Novia; Septi Putri Lestari
Jurnal Insan Farmasi Indonesia Vol 5 No 1 (2022): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v5i1.914

Abstract

Senggani fruit (Melastoma malabathricum L.) is one of the wild plants whose leaves are usually used by the community as a medicine for wounds and cancer sores. Senggani fruit contains high anthocyanins and antioxidants, which are very good for preventing cancer in the body. The purpose of this research is to make syrup of Senggani fruit juice. The formulation of Senggani fruit juice syrup was made by heating method at 54°C with various concentrations of F0, F1 (5%), F2 (6%) and F3 (8%). Then, the physical properties were tested, namely organoleptic, viscosity test, pH test, homogenity test, hedonic test and descriptive test. From testing the physical properties of the syrup formulation of Senggani fruit, it was found that the organoleptic test of F2 and F3 showed a change in consistency; for the pH test results the four formulas ranged from 3.98 to 7.07; the homogeneity test on F2 and F3 was not homogeneous, there were black grains at the 3rd week; then the viscosity test of syrup preparations F2 and F3 obtained an average result of 30 - 51.33 cPs; as well as hedonic and descriptive tests with the criteria of somewhat like - like the most preferred is F3.
FORMULASI DAN UJI PENETAPAN KADAR VITAMIN C EKSTRAK BIJI TELANG MUDA (Clitoria ternatea L.) PADA SEDIAAN BODY LOTION karina anjani susetyo; Tri Yanuarto; Ariesa Oktamauri
Jurnal Komunitas Farmasi Nasional Vol. 6 No. 01 (2026): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Young butterfly pea seeds (Clitoria ternatea L.) are known to contain natural antioxidants, including vitamin C, which are beneficial in protecting the skin from free radical damage. Vitamin C is an important antioxidant that plays a role in counteracting free radicals and maintaining body health. This study aimed to formulate a body lotion from young butterfly pea seed extract by varying the extract concentration (F1:2%; F2:3%; F3:4%) and then conducting an evaluation. The evaluation included physical properties (organoleptic, homogeneity, emulsion, viscosity, spreadability, and adhesion), chemical properties (pH), and vitamin C levels were determined using UV-Vis spectrophotometry. The results of the study showed that all physical properties test formulas (organoleptic, homogeneity, emulsion, viscosity, spreadability and adhesiveness) and chemical tests (pH) had met the requirements and the highest vitamin C content was in formula F3, namely 46.95%. Keywords: Young Butterfly Pea Seed Extract, Body Lotion, Vitamin C Content Determination.
FORMULASI DAN UJIANTIINFLAMASI SALEP EKSTRAK RESIN JERNANG (Daemonorops Draco (Wild)) Blume PADA MENCIT JANTAN PUTIH(Wistar). Feliza Mayasari; Devi Novia; Tri Yanuarto
Jurnal Komunitas Farmasi Nasional Vol. 5 No. 02 (2025): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Abstract

Jernang sap (Daemonorops draco (Willd.) Blume) is the exudate of the jernang rattan fruit which has been traditionally used as a traditional medicine. The active compounds contained in it include flavonoids, saponins, terpenoids, alkaloids, and phenolics, which are known to have potential as anti-inflammatory agents. This study aims to design a topical preparation in the form of an ointment from jernang sap extract and to test its physical quality and anti-inflammatory effects in vivo. The extraction process was carried out using a maceration technique using 96% ethanol, then the extract obtained was formulated into three variations of ointment with different concentrations (F1: 1%, F2: 2%, F3: 3%), using a base of vaseline flavum, lanolin, and propyl paraben as a preservative. Testing the physical quality of the ointment included organoleptic examination, homogeneity, pH value, spreadability, and viscosity. Anti-inflammatory activity was tested using male mice (Mus musculus) induced with 1% carrageenan on the paws, and the edema volume was measured using a plethysmometer. The results showed that an ointment made from jernang extract could be prepared with stable physical properties during storage. ANOVA analysis and further testing showed that formulas with higher concentrations (F2 and F3) provided a significant inflammation-inhibiting effect, nearly comparable to the positive control, a 2.5% hydrocortisone ointment. Thus, jernang extract has potential as a natural ingredient for topical anti-inflammatory ointments.
Identifikasi Flavonoid Ekstrak Fraksi Etil Asetat Daun Asam Jawa terhadap Streptococcus mutans Intan Harlesi; Devi Novia; Tri Yanuarto; Luky Dharmayanti
Jurnal Ilmiah Manusia Dan Kesehatan Vol. 9 No. 3 (2026): Jurnal Ilmiah MANUSIA DAN KESEHATAN
Publisher : FAKULTAS ILMU KESEHATAN UNIVERSITAS MUHAMMADIYAH PAREPARE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31850/makes.v9i3.4583

Abstract

Bakteri Streptococcus mutans diketahui memiliki peranan dalam proses terjadinya karies gigi, sehingga diperlukan alternatif antibakteri yang berasal dari bahan alam. Penelitian ini dilakukan untuk mengetahui keberadaan senyawa flavonoid dalam ekstrak fraksi etil asetat daun asam jawa (Tamarindus indica L.), menganalisis kandungan flavonoid total, serta menguji aktivitas antibakterinya terhadap Streptococcus mutans. Daun asam jawa diekstraksi melalui proses maserasi dengan etanol 96%, kemudian dilanjutkan dengan fraksinasi menggunakan etil asetat. Keberadaan flavonoid dikonfirmasi melalui skrining fitokimia dan Kromatografi Lapis Tipis (KLT), sedangkan kandungan flavonoid total dianalisis menggunakan spektrofotometer UV-Vis dengan kuarsetin sebagai standar pada panjang gelombang 432 nm. Aktivitas antibakteri diuji menggunakan teknik difusi cakram dengan konsentrasi 25%, 50%, dan 75%, menggunakan chlorhexidine gluconate 0,2% sebagai kontrol positif dan DMSO 10% sebagai kontrol negatif. Hasil penelitian menunjukkan bahwa ekstrak fraksi etil asetat positif mengandung flavonoid dengan kadar flavonoid total sebesar 4,091%. Nilai Rf sampel sebesar 0,94 dan Rf kuarsetin sebesar 0,88 menunjukkan selisih nilai Rf sebesar 0,06. Rerata diameter zona hambat yang diperoleh pada konsentrasi 25%, 50%, dan 75% masing-masing sebesar 11,74; 16,53; dan 21,48 mm, sedangkan kontrol positif menghasilkan diameter hambat sebesar 11,27 mm dan kontrol negatif tidak membentuk zona hambat. Analisis One-Way ANOVA memperlihatkan adanya perbedaan yang signifikan antarperlakuan (p<0,05), dengan konsentrasi 75% menghasilkan daya hambat paling tinggi. Dengan demikian, ekstrak fraksi etil asetat daun asam jawa positif mengandung flavonoid dan memiliki aktivitas antibakteri terhadap Streptococcus mutans, dengan konsentrasi 75% sebagai perlakuan yang memberikan efektivitas terbaik
Co-Authors Ariesa Oktamauri Devi Novia dharmayanti, luky dharmayanti Feliza Mayasari Intan Harlesi karina anjani susetyo Septi Putri Lestari