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All Journal Pharmacology and Clinical Pharmacy Research CARADDE: Jurnal Pengabdian Kepada Masyarakat
Hesti Riasari
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Education Medicine & Pharmacology Social Sciences

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Comparison of Anti-Inflammatory Activity between Fermented and Dried Breadfruit Leaves Extract Hesti Riasari; Sani N. Fitriansyah; Oktamuman Putra
Pharmacology and Clinical Pharmacy Research Vol 3, No 3
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (321.616 KB) | DOI: 10.15416/pcpr.v3i3.19973

Abstract

Breadfruit leaves (Artocarpus altilis) have been empirically used to treat inflammation. Biosynthesis process such as fermentation can possibly changes the composition of secondary metabolites in breadfruit leaves. The aim of this study was to compare the anti-inflammatory activity between fermented and natural-dried breadfruit leaves extract. Fermented and dried breadfruit leaves were extracted with soxhlet device using methanol solvent. The anti-inflammatory activity of both extracts were evaluated using carrageenan (1% w/v) foot edema model of inflammation in male Wistar rats. The edema was measured with plethysmometer every 1 hour for 6 hours. The results showed that both extracts exhibited anti-inflammatory activity. 50 mg and 100 mg fermented leaves extracts exhibited 37.17% and 71.82% inhibition, while the same concentrations of dried extract exhibited 39.50% and 57.72%, inhibiton respectively. In conclusion, the best anti-inflammatory activity was shown by fermented breadfruit leaves extract.Keywords: Artocarpus altilis, anti-inflammatory, breadfruit, fermentation
Edukasi Berbasis Literasi untuk Meningkatkan Pengetahuan Masyarakat tentang Khasiat Rimpang Herbal Siti Uswatun Hasanah; Wibowo, Diki Prayugo; Hesti Riasari; Sani Nurlaela Fitriansyah; Irma Erika Herawati
CARADDE: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 3 (2026): April
Publisher : Ilin Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31960/caradde.v8i3.3225

Abstract

Medicinal plants can consist of herbs or specific parts of plants, such as spices commonly used in cooking. In today’s digital era, the dissemination of information regarding the use of herbal medicine plays an important role in public education. During the Industry 4.0 era, people can easily access various information independently through websites and online learning platforms. However, the utilization of local herbal plants remains relatively low due to limited public understanding of their potential as medicinal herbs. This community service activity aimed to improve the knowledge and understanding of the residents of Ciburuan Hamlet, Jingkang Village, Bandung Regency, regarding herbal plants, particularly the rhizomes of ginger, turmeric, aromatic ginger (kencur), and galangal (lengkuas). Education was carried out through interactive education sessions and brochure distribution. The methods included preliminary observation, interviews, and questionnaires. The results showed a significant increase in participants’ knowledge about the active compounds and pharmacological activities of herbal plants. Before the activity, most participants were unfamiliar with the bioactive components of herbal rhizomes and only knew their traditional uses. After the interactive session, all participants were able to recognize the chemical constituents and mechanisms of action of these herbs as antioxidants, antibacterials, and anti-inflammatory agents. This activity demonstrates that digital and visual literacy-based education can effectively enhance public awareness (83%) and confidence in using herbal medicine as an alternative for maintaining family health.
Co-Authors Irma Erika Herawati Oktamuman Putra Sani N. Fitriansyah Sani nurlaela fitriansyah Siti Uswatun Hasanah Wibowo, Diki Prayugo