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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JMM (Jurnal Masyarakat Mandiri) Journal of Midwifery and Nursing Jurnal Ners Science Midwifery Jurnal Mandala Pengabdian Masyarakat Journal of Education Research West Science Interdisciplinary Studies West Science Interdisciplinary Studies JI-KES (Jurnal Ilmu Kesehatan)
Wibowo, Diki Prayugo
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Literature riview: Ethnoparmacognosy, chemical content, and pharmacological activity of Kirinyuh (chromolaena odorata L.) leaves Wulandari, Indri; Wirasutisna, Komar R; Mariani, Ria; Wibowo, Diki Prayugo
Journal of Midwifery and Nursing Vol. 6 No. 1 (2024): January: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v6i1.4496

Abstract

Chromolaena odorata L. is a foliaceous plant that has its origins in the Americas and has since proliferated across Indonesia, Africa, and the Pacific region. Chromolaena odorata leaf is a botanical specimen that possesses alkaloids, flavonoids, tannins, saponins, and steroids, which are known for their therapeutic properties. The approach used in this article review involves conducting online literature studies. The research data consists of publications obtained from respected journal sites such as Google Scholar, PubMed, Science Direct, and Research Gate.The articles were chosen from publications that covered the time frame from 2013 and 2023. The purpose of this article is to present detailed information regarding the ethno-pharmacognosy, chemical composition, and pharmacological activity of Kirinyuh leaves (Chromomolaena odorata L.).
Physicochemical Parameters, Phytochemical Screening, and Antioxidant Activity of Capsicum annuum var. grossum Leaves From Indonesia Mariani, Ria; Perdana, Farid; Mawaddah, Linda Rabbayani; Wibowo, Diki Prayugo
Journal of Midwifery and Nursing Vol. 6 No. 2 (2024): May: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v6i2.5039

Abstract

Dietary plants are believed to contain antioxidants that have positive effects on human health. Free radicals, other reactive oxygen and nitrogen spesies can be eliminated by antioxidants. The presence of flavonoids and phenol in paprika (Capsicum annuum var. grossum) fruit contributes to its antioxidant properties. The phytochemistry and antioxidant activity of paprika leaves—especially those cultivated in Indonesia—have not been extensively studied. The aim of this study to investigate psychochemical parameters, phytochemical screening and antioxidant activity of paprika leaves from Indonesia. Several physicochemical parameters and phytochemical screening test were done base on Indonesian Herbs Pharmacopoeia. Antioxidant activity test using DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Dry powder of paprika leaves have some physicochemical parameters which part of its characteristic. Dry powder and extract of paprika leaves contains flavonoid, saponin, phenol and steroid/triterpenoid. The findings of the antioxidant test indicated that the standard vitamin C exhibited an IC50 value of 6.22 µg/ml. In contrast, the extract, n-hexane fraction, ethyl acetate fraction, and water fraction demonstrated IC50 values of 6.41, 9.12, 8.96, and 10.58 µg/ml, respectively. There was potential for paprika leaves to be developed as a natural source of antioxidants.
Efektifitas Komunikasi Persuasif dalam Mendorong Perubahan Perilaku Mahasiswa Farmasi Wasngadiredja, Pupu Fujriani; Wibowo, Diki Prayugo
Journal of Education Research Vol. 5 No. 1 (2024)
Publisher : Perkumpulan Pengelola Jurnal PAUD Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37985/jer.v5i1.676

Abstract

Penelitian ini bertujuan untuk mengeksplorasi dan memahami fenomena perubahan perilaku mahasiswa farmasi yang telah habis masa studi dan nyaris menghadapi Drop Out (DO). Fokus utama adalah efektifitas Komunikasi Persuasif dari Tim Pelaksana Bimbingan dan Konseling (TPBK) sebagai agen kunci dalam mendukung mahasiswa mengatasi tantangan seperti penurunan motivasi, masalah keluarga, kesulitan mengatur waktu, kendala biaya dan hambatan berkomunikasi dengan dosen pembimbing. Melalui metode penelitian kualitatif dengan pendekatan fenomenologi, hasil menunjukkan bahwa pesan persuasif TPBK memberikan dukungan moral, membangkitkan semangat, dan meningkatkan pemahaman tentang pentingnya menyelesaikan tugas akhir. Kesimpulan triangulator menegaskan bahwa komunikasi persuasif efektif digunakan dalam menciptakan perubahan positif, termasuk peningkatan motivasi dan keterbukaan untuk bekerja sama. Temuan ini memberikan kontribusi signifikan untuk meningkatkan kualitas layanan bimbingan dan konseling, memberikan pemahaman lebih dalam tentang peran strategis Komunikasi Persuasif dalam mendorong perubahan perilaku mahasiswa farmasi yang berisiko DO
Cross-Cultural Analysis of the Role of Traditional Medicine in Health Access in Indonesia Abdullah, Vera Iriani; Wahidin, Wahidin; Wibowo, Diki Prayugo; Mariani, Ria
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.279

Abstract

This study investigates the contribution of traditional medicine on health care access in Indonesia through a quantitative cross-cultural approach. Utilizing a sample of 350 individuals that is diverse in terms of age, gender, and ethnic background, the study investigates the prevalence and characteristics that impact the use of traditional medicine. The findings show that traditional healing methods are heavily relied upon, especially by elderly people and members of specific ethnic groups. The necessity for culturally responsive healthcare practices is highlighted by the discovery that cultural beliefs are important determinants of health-seeking behaviour. The results add to the growing body of knowledge about the integration of traditional medicine into modern healthcare systems by highlighting the significance of customizing therapies to the many cultural settings found throughout Indonesia.
Analyzing Knowledge Networks in Health Care through Collaborative Research Exploration Wibowo, Diki Prayugo; Mariani, Ria; Aldo, Novian; Andarmoyo, Sulistyo
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.293

Abstract

The exploration of collaborative research in healthcare is a dynamic and multifaceted endeavor, as evidenced by analysis of influential articles, citation patterns, and keyword frequencies. Davenport and Prusak's seminal work on knowledge management serves as a foundational foundation, emphasizing the critical role of effective knowledge utilization and sharing in collaborative healthcare research. This research explores linkages with other influential articles, including Scott's examination of social network analysis, Star and Griesemer's insights on institutional ecology, and Tranfield et al.'s methodology on evidence-based knowledge management. Further analysis extends to works on thematic analysis, inter-organizational collaboration, cancer genomics, and qualitative research methods, all of which contribute to a rich tapestry of collaborative healthcare research. Keyword analysis revealed thematic priorities, with a major focus on "Care" and "Experience", emphasizing the human dimension of healthcare. Challenges, technology and organizational aspects emerged as prominent themes, reflecting a holistic approach to collaborative exploration. The interplay between keywords such as "Dynamic", "Mechanisms", and "Performance" underscores the evolving nature of collaborative efforts and the need for strategic mechanisms to address challenges and improve performance. The analysis also highlights contemporary concerns, including the impact of the COVID-19 pandemic, barriers to collaboration, and the intersection of mental health and social media.
Determination of Phenolic and Flavonoid Total Levels and Antioxidant Activity of Ethanol, Ethyl Acetate, and n-Hexane Extracts of Citrus reticulata Blanco Fruit Peel by DPPH and ABTS Methods: Penetapan Kadar Total Fenol dan Flavonoid serta Aktivitas Antioksidan Ekstrak Etanol, Etil Asetat, dan n-Heksan Kulit Buah Citrus reticulata Blanco dengan Metode DPPH dan ABTS Fadhlillah, Faizah Min; Miranti, Mila; Wibowo, Diki Prayugo; Purkon, Dicki Bakhtiar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16399

Abstract

Background: The peel of the fruit Citrus reticulata Blanco has long been used in traditional medicine due to its various properties. Traditional medicine from certain parts of medicinal plants is related to the content of bioactive compounds from the fruit's peel, such as phenolic compounds and flavonoids that can help protect the body from damage caused by free radicals. Objectives: This study aimed to evaluate the total levels of phenolics and flavonoids as well as antioxidants from ethanol, ethyl acetate, and n-hexane extracts from the skin of Citrus reticulata Blanco using DPPH (2,2-diphenyl-1-picrylhydrazil) and ABTS (2,2'-azinobis-(3-ethylbenzothiazolin-6-sulphonate))) methods. Material and Methods: The extraction process was carried out using the maceration ion method with ethanol, ethyl acetate, and n-hexane solvents at room temperature for 24 hours. Total phenolic and flavonoid levels in the extract were determined using UV-Vis spectrophotometry, and antioxidant activity testing was determined based on the extract's ability to neutralize free radicals from DPPH and ABTS. Results: The results showed that the ethanol extract of Citrus reticulata Blanco fruit peel had higher total phenolic and flavonoid levels compared to ethyl acetate and n-hexane extracts. The total phenolic levels in ethanol, ethyl acetate, and n-hexane extracts were 142.02, 74.60, and 57.17 mg GAE/g, respectively. The total flavonoid levels in ethanol, ethyl acetate, and n-hexane extracts were 45.96, 40.22, and 38.54 mg QE/g, respectively. In addition, ethanol extract has also shown the strongest antioxidant activity based on the results of testing with DPPH and ABTS methods. The inhibitory concentration (IC50) of ethanol extract against DPPH and ABTS methods was 23,490 μg/mL and 31,971 μg/mL, respectively, with strong category. Conclusions: This study shows that the skin of Citrus reticulata Blanco fruit contains phenolic compounds and flavonoids that have the potential as natural antioxidants, with ethanol extract being the most promising related to total phenolic and flavonoid levels and antioxidant activity. This information can be used as a basis for developing pharmaceutical dosage products and health supplements that can potentially improve antioxidant/health status in the body.
Analisis Efektivitas Program POLITERA dalam Meningkatkan Literasi Siswa Wasngadiredja, Pupu Fujriani; Purwanto, Bambang; Wibowo, Diki Prayugo
Journal of Education Research Vol. 5 No. 4 (2024)
Publisher : Perkumpulan Pengelola Jurnal PAUD Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37985/jer.v5i4.1838

Abstract

Literasi adalah kemampuan dasar yang penting untuk berfungsi efektif dalam era informasi dan globalisasi. Pendidikan berperan sentral dalam mengembangkan literasi siswa, dan SMP Taruna Bakti mengimplementasikan Program Poin Literasi (POLITERA) untuk memotivasi siswa dan menilai aktivitas literasi mereka secara terukur. Penelitian ini mengevaluasi efektivitas program tersebut melalui pendekatan kualitatif deskriptif dengan observasi dan wawancara. Fokus penelitian meliputi keaktifan siswa, dukungan guru dan orang tua, serta peningkatan pengetahuan literasi. Hasil menunjukkan bahwa POLITERA meningkatkan partisipasi siswa dalam kegiatan literasi seperti membaca dan diskusi, dengan dukungan guru dan orang tua yang krusial. Program ini juga meningkatkan kemampuan membaca, menulis, dan pemahaman siswa, serta memberikan informasi yang jelas melalui laporan rapor. POLITERA dapat dijadikan model program literasi di sekolah lain, berkontribusi pada pengembangan literasi dan kualitas pendidikan di Indonesia.
Phytochemical Screening And Antioxidant Activities Of Several Bamboo Leaves Species From Garut Indonesia Wibowo, Diki Prayugo; Muharom, Ahmad Wahid; Noviyanti, Noviyanti; Mariani, Ria
Jurnal Ners Vol. 9 No. 3 (2025): JULI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i3.46935

Abstract

Tumbuhan kaya akan senyawa antioksidan yang memberikan perlindungan terhadap berbagai penyakit yang berkaitan dengan radikal bebas. Senyawa antioksidan tersebut umumnya disintesis sebagai metabolit sekunder. Salah satu tumbuhan yang memiliki aktivitas antioksidan adalah bambu. Beberapa spesies bambu yang tumbuh di daerah Garut antara lain bambu kuning, bambu aur, dan bambu tali. Penelitian mengenai metabolit sekunder dan aktivitas antioksidan dari daun bambu yang berasal dari Garut belum ada. Oleh karena itu, penelitian ini bertujuan untuk mengkaji kandungan metabolit sekunder dan aktivitas antioksidan dari daun ketiga spesies bambu tersebut. Penapisan fitokimia dilakukan dengan menggunakan beberapa pereaksi identifikasi, sedangkan uji aktivitas antioksidan menggunakan metode DPPH (2,2-difenil-1-pikrilhidrazil). Hasil penapisan fitokimia menunjukkan bahwa serbuk simplisia dan ekstrak daun bambu kuning, bambu aur, dan bambu tali mengandung senyawa fenol, saponin, dan steroid/triterpen. Hasil uji aktivitas antioksidan menunjukkan bahwa ekstrak daun bambu kuning, bambu aur, dan bambu tali memiliki aktivitas antioksidan yang kuat, dengan nilai IC50 masing-masing sebesar 51,64; 82,04; dan 76,67 µg/ml. Penelitian ini menunjukkan bahwa daun bambu kuning, bambu aur dan bambu tali yang berasal dari Garut memiliki potensi besar sebagai sumber antioksidan alami yang dapat membantu mencegah dan mengobati penyakit yang berkaitan dengan stres oksidatif.
UPAYA PENINGKATAN PENGETAHUAN KESEHATAN MENTAL PADA REMAJA DALAM MEWUJUDKAN GENERASI Z YANG BERIMAN Lubis, Novriyanti; Annafiah, Salma; Wibowo, Diki Prayugo; Fadhilah, Salma Firyal; Sudrajat, Awang; Prasetiawati, Riska
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 3 (2025): Juni
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i3.30365

Abstract

Abstrak: Generasi Z atau Gen Z merupakan generasi yang lahir pada 1997-2012. Perkembangan pola pikir kritis adalah pada saat usia remaja. WHO menyebutkan penduduk dengan rentan usia 10-19 tahun menyumbangkan sebanyak 16% beban penyakit, cedera, dan gangguan mental emosional. Hal ini disebabkan oleh kurangnya edukasi dan kesadaran masyarakat terhadap penanggulangan kesehatan mental pada anak dan remaja. Kasus-kasus ini disebabkan oleh ketidaktahuan dan dan kurangnya kesadaran mengenai kesehatan mental. Penyuluhan ini dilakukan agar kondisi kesehatan mental remaja di MTS Babussalam yang berlokasi di Desa Barusuda Kecamatan Cigedug, Kabupaten Garut, Jawa Barat lebih baik lagi dan adanya peningkatan pengetahuan mengenai kesehatan mental. Metode penyuluhan dilakukan melalui presentasi langsung. Total siswa yang berpartisipasi dalam peenyuluhan ini sebanyak 57 siswa. Instrumen yang digunakan dalam metode ini adalah lembar kuisioner. Hasil penyuluhan menunjukkan sebanyak 77,2% siswa yang mengikuti kegiatan sosialisasi diketahui telah paham terhadap pentingnya kesehatan mental pada remaja. Selain itu, pemahaman responden terhadap perilaku tidak baik bagi kesehatan mental yakni sebanyak 82,5% siswa dan sebanyak 75,4% siswa paham akan kondisi ketika kesehatan mental tidak baik. Diharapkan penyuluhan ini dapat menjadi landasan untuk mengetahui cara penanganan dalam kesehatan mental secara preventif dan promotif pada kesehatan jiwa remaja yang di dalamnya melibatkan di lingkungan sekolah termasuk guru dan teman sebaya sehingga remaja mampu memiliki faktor protektor yang baik dan mampu mengatasi masalah yang terjadi dengan adaptif.Abstract: The development of critical thinking is during adolescence. WHO states that the vulnerable population aged 10-19 years contributes as much as 16% of the burden of disease, injury and mental-emotional disorders. This is caused by a lack of education and public awareness of mental health management in children and adolescents. These cases are caused by ignorance and lack of awareness regarding mental health. This counseling was carried out to find out how students know about adolescent mental health at MTS Babussalam which is located in Barusuda Village, Cigedug District, Garut Regency, Total participating in this counseling were 57 students. The instrument used in this method is a questionnaire sheet. Data were analyzed with descriptive analysis techniques. The results of the counseling showed that 77.2% of the students who took part in the socialization activities were known to have understood the importance of mental health in adolescents. In addition, respondents' understanding of behavior that is not good for mental health, namely as many as 82.5% of students and as many as 75.4% of students understand the conditions when mental health is not good. It is hoped that this counseling can become the basis for knowing how to deal with preventive and promotive mental health in adolescent mental health which involves the school environment including teachers and peers so that adolescents are able to have good protective factors and are able to overcome problems that occur adaptively.
Review: Antioxidant Activity Of Indonesian Banana Peels Mariani, Ria; Noviyanti, Noviyanti; Inayah, Rahifa; Wibowo, Diki Prayugo
Jurnal Ners Vol. 9 No. 4 (2025): OKTOBER 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v9i4.50701

Abstract

Pisang merupakan buah yang paling banyak dikonsumsi di dunia dan memiliki berbagai manfaat kesehatan. Kulit pisang, yang sering dianggap sebagai limbah, ternyata mengandung senyawa bioaktif dengan aktivitas antioksidan yang signifikan. Aktivitas antioksidan dari kulit pisang telah banyak dilaporkan, termasuk kulit pisang dari Indonesia. Review ini membahas aktivitas antioksidan kulit pisang Indonesia serta kandungan senyawa aktif di dalamnya. Sejumlah penelitian menunjukkan bahwa terdapat ekstrak kulit pisang dari Indonesia yang memiliki aktivitas antioksidan sangat kuat, antara lain ekstrak kulit pisang Ambon mentah, kulit pisang Barangan mentah, dan kulit pisang Muli. Penelitian juga menunjukkan bahwa kulit pisang yang masih mentah memiliki aktivitas antioksidan yang lebih tinggi dibandingkan dengan yang sudah matang, yang disebabkan oleh kandungan flavonoid dan tanin yang lebih tinggi. Potensi antioksidan dari kulit pisang terutama disebabkan oleh keberadaan flavonoid, saponin dan tanin yang berperan penting dalam menetralkan radikal bebas.
Co-Authors abdullah, vera iriani Aldo, Novian Aldo, Novian Andarmoyo, Sulistyo Annafiah, Salma Bambang Purwanto Dicki Bakhtiar Purkon Fadhilah, Salma Firyal Faizah Min Fadhlillah Fitriansyah, Sani Nurlaela Inayah, Rahifa Indri Wulandari, Indri Irma Erika Herawati Komar Ruslan Wirasutisna Mawaddah, Linda Rabbayani Miranti, Mila Muharom, Ahmad Wahid Najwa Najwa Normila Normila Noviyanti Noviyanti, Noviyanti Novriyanti Lubis, Novriyanti Perdana, Farid Putri , Yola Desnera Restiasari, Anggi Ria Mariani Riasari, Hesti Riska Prasetiawati, Riska S, Irmawati Siti Rahma Siti Uswatun Hasanah Sudrajat, Awang Sutriyawan, Agung Tristiyanti, Deby Wahidin Wahidin Wasngadiredja, Pupu Fujriani Wirasutisna, Komar R Yusuf, Aldy Fadlillah