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Literature riview: Ethnoparmacognosy, chemical content, and pharmacological activity of Kirinyuh (chromolaena odorata L.) leaves Wulandari, Indri; Wirasutisna, Komar R; Mariani, Ria; Wibowo, Diki Prayugo
Journal of Midwifery and Nursing Vol. 6 No. 1 (2024): January: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v6i1.4496

Chromolaena odorata L. is a foliaceous plant that has its origins in the Americas and has since proliferated across Indonesia, Africa, and the Pacific region. Chromolaena odorata leaf is a botanical specimen that possesses alkaloids, flavonoids, tannins, saponins, and steroids, which are known for their therapeutic properties. The approach used in this article review involves conducting online literature studies. The research data consists of publications obtained from respected journal sites such as Google Scholar, PubMed, Science Direct, and Research Gate.The articles were chosen from publications that covered the time frame from 2013 and 2023. The purpose of this article is to present detailed information regarding the ethno-pharmacognosy, chemical composition, and pharmacological activity of Kirinyuh leaves (Chromomolaena odorata L.).

Physicochemical Parameters, Phytochemical Screening, and Antioxidant Activity of Capsicum annuum var. grossum Leaves From Indonesia Mariani, Ria; Perdana, Farid; Mawaddah, Linda Rabbayani; Wibowo, Diki Prayugo
Journal of Midwifery and Nursing Vol. 6 No. 2 (2024): May: Health Science
Publisher : Institute Of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/jmn.v6i2.5039

Dietary plants are believed to contain antioxidants that have positive effects on human health. Free radicals, other reactive oxygen and nitrogen spesies can be eliminated by antioxidants. The presence of flavonoids and phenol in paprika (Capsicum annuum var. grossum) fruit contributes to its antioxidant properties. The phytochemistry and antioxidant activity of paprika leaves—especially those cultivated in Indonesia—have not been extensively studied. The aim of this study to investigate psychochemical parameters, phytochemical screening and antioxidant activity of paprika leaves from Indonesia. Several physicochemical parameters and phytochemical screening test were done base on Indonesian Herbs Pharmacopoeia. Antioxidant activity test using DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Dry powder of paprika leaves have some physicochemical parameters which part of its characteristic. Dry powder and extract of paprika leaves contains flavonoid, saponin, phenol and steroid/triterpenoid. The findings of the antioxidant test indicated that the standard vitamin C exhibited an IC50 value of 6.22 µg/ml. In contrast, the extract, n-hexane fraction, ethyl acetate fraction, and water fraction demonstrated IC50 values of 6.41, 9.12, 8.96, and 10.58 µg/ml, respectively. There was potential for paprika leaves to be developed as a natural source of antioxidants.

Efektifitas Komunikasi Persuasif dalam Mendorong Perubahan Perilaku Mahasiswa Farmasi Wasngadiredja, Pupu Fujriani; Wibowo, Diki Prayugo
Journal of Education Research Vol. 5 No. 1 (2024)
Publisher : Perkumpulan Pengelola Jurnal PAUD Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37985/jer.v5i1.676

Penelitian ini bertujuan untuk mengeksplorasi dan memahami fenomena perubahan perilaku mahasiswa farmasi yang telah habis masa studi dan nyaris menghadapi Drop Out (DO). Fokus utama adalah efektifitas Komunikasi Persuasif dari Tim Pelaksana Bimbingan dan Konseling (TPBK) sebagai agen kunci dalam mendukung mahasiswa mengatasi tantangan seperti penurunan motivasi, masalah keluarga, kesulitan mengatur waktu, kendala biaya dan hambatan berkomunikasi dengan dosen pembimbing. Melalui metode penelitian kualitatif dengan pendekatan fenomenologi, hasil menunjukkan bahwa pesan persuasif TPBK memberikan dukungan moral, membangkitkan semangat, dan meningkatkan pemahaman tentang pentingnya menyelesaikan tugas akhir. Kesimpulan triangulator menegaskan bahwa komunikasi persuasif efektif digunakan dalam menciptakan perubahan positif, termasuk peningkatan motivasi dan keterbukaan untuk bekerja sama. Temuan ini memberikan kontribusi signifikan untuk meningkatkan kualitas layanan bimbingan dan konseling, memberikan pemahaman lebih dalam tentang peran strategis Komunikasi Persuasif dalam mendorong perubahan perilaku mahasiswa farmasi yang berisiko DO

Cross-Cultural Analysis of the Role of Traditional Medicine in Health Access in Indonesia Abdullah, Vera Iriani; Wahidin, Wahidin; Wibowo, Diki Prayugo; Mariani, Ria
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.279

This study investigates the contribution of traditional medicine on health care access in Indonesia through a quantitative cross-cultural approach. Utilizing a sample of 350 individuals that is diverse in terms of age, gender, and ethnic background, the study investigates the prevalence and characteristics that impact the use of traditional medicine. The findings show that traditional healing methods are heavily relied upon, especially by elderly people and members of specific ethnic groups. The necessity for culturally responsive healthcare practices is highlighted by the discovery that cultural beliefs are important determinants of health-seeking behaviour. The results add to the growing body of knowledge about the integration of traditional medicine into modern healthcare systems by highlighting the significance of customizing therapies to the many cultural settings found throughout Indonesia.

Analyzing Knowledge Networks in Health Care through Collaborative Research Exploration Wibowo, Diki Prayugo; Mariani, Ria; Aldo, Novian; Andarmoyo, Sulistyo
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.293

The exploration of collaborative research in healthcare is a dynamic and multifaceted endeavor, as evidenced by analysis of influential articles, citation patterns, and keyword frequencies. Davenport and Prusak's seminal work on knowledge management serves as a foundational foundation, emphasizing the critical role of effective knowledge utilization and sharing in collaborative healthcare research. This research explores linkages with other influential articles, including Scott's examination of social network analysis, Star and Griesemer's insights on institutional ecology, and Tranfield et al.'s methodology on evidence-based knowledge management. Further analysis extends to works on thematic analysis, inter-organizational collaboration, cancer genomics, and qualitative research methods, all of which contribute to a rich tapestry of collaborative healthcare research. Keyword analysis revealed thematic priorities, with a major focus on "Care" and "Experience", emphasizing the human dimension of healthcare. Challenges, technology and organizational aspects emerged as prominent themes, reflecting a holistic approach to collaborative exploration. The interplay between keywords such as "Dynamic", "Mechanisms", and "Performance" underscores the evolving nature of collaborative efforts and the need for strategic mechanisms to address challenges and improve performance. The analysis also highlights contemporary concerns, including the impact of the COVID-19 pandemic, barriers to collaboration, and the intersection of mental health and social media.

Determination of Phenolic and Flavonoid Total Levels and Antioxidant Activity of Ethanol, Ethyl Acetate, and n-Hexane Extracts of Citrus reticulata Blanco Fruit Peel by DPPH and ABTS Methods: Penetapan Kadar Total Fenol dan Flavonoid serta Aktivitas Antioksidan Ekstrak Etanol, Etil Asetat, dan n-Heksan Kulit Buah Citrus reticulata Blanco dengan Metode DPPH dan ABTS Fadhlillah, Faizah Min; Miranti, Mila; Wibowo, Diki Prayugo; Purkon, Dicki Bakhtiar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16399

Background: The peel of the fruit Citrus reticulata Blanco has long been used in traditional medicine due to its various properties. Traditional medicine from certain parts of medicinal plants is related to the content of bioactive compounds from the fruit's peel, such as phenolic compounds and flavonoids that can help protect the body from damage caused by free radicals. Objectives: This study aimed to evaluate the total levels of phenolics and flavonoids as well as antioxidants from ethanol, ethyl acetate, and n-hexane extracts from the skin of Citrus reticulata Blanco using DPPH (2,2-diphenyl-1-picrylhydrazil) and ABTS (2,2'-azinobis-(3-ethylbenzothiazolin-6-sulphonate))) methods. Material and Methods: The extraction process was carried out using the maceration ion method with ethanol, ethyl acetate, and n-hexane solvents at room temperature for 24 hours. Total phenolic and flavonoid levels in the extract were determined using UV-Vis spectrophotometry, and antioxidant activity testing was determined based on the extract's ability to neutralize free radicals from DPPH and ABTS. Results: The results showed that the ethanol extract of Citrus reticulata Blanco fruit peel had higher total phenolic and flavonoid levels compared to ethyl acetate and n-hexane extracts. The total phenolic levels in ethanol, ethyl acetate, and n-hexane extracts were 142.02, 74.60, and 57.17 mg GAE/g, respectively. The total flavonoid levels in ethanol, ethyl acetate, and n-hexane extracts were 45.96, 40.22, and 38.54 mg QE/g, respectively. In addition, ethanol extract has also shown the strongest antioxidant activity based on the results of testing with DPPH and ABTS methods. The inhibitory concentration (IC50) of ethanol extract against DPPH and ABTS methods was 23,490 Î¼g/mL and 31,971 Î¼g/mL, respectively, with strong category. Conclusions: This study shows that the skin of Citrus reticulata Blanco fruit contains phenolic compounds and flavonoids that have the potential as natural antioxidants, with ethanol extract being the most promising related to total phenolic and flavonoid levels and antioxidant activity. This information can be used as a basis for developing pharmaceutical dosage products and health supplements that can potentially improve antioxidant/health status in the body.

Analisis Efektivitas Program POLITERA dalam Meningkatkan Literasi Siswa Wasngadiredja, Pupu Fujriani; Purwanto, Bambang; Wibowo, Diki Prayugo
Journal of Education Research Vol. 5 No. 4 (2024)
Publisher : Perkumpulan Pengelola Jurnal PAUD Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37985/jer.v5i4.1838

Literasi adalah kemampuan dasar yang penting untuk berfungsi efektif dalam era informasi dan globalisasi. Pendidikan berperan sentral dalam mengembangkan literasi siswa, dan SMP Taruna Bakti mengimplementasikan Program Poin Literasi (POLITERA) untuk memotivasi siswa dan menilai aktivitas literasi mereka secara terukur. Penelitian ini mengevaluasi efektivitas program tersebut melalui pendekatan kualitatif deskriptif dengan observasi dan wawancara. Fokus penelitian meliputi keaktifan siswa, dukungan guru dan orang tua, serta peningkatan pengetahuan literasi. Hasil menunjukkan bahwa POLITERA meningkatkan partisipasi siswa dalam kegiatan literasi seperti membaca dan diskusi, dengan dukungan guru dan orang tua yang krusial. Program ini juga meningkatkan kemampuan membaca, menulis, dan pemahaman siswa, serta memberikan informasi yang jelas melalui laporan rapor. POLITERA dapat dijadikan model program literasi di sekolah lain, berkontribusi pada pengembangan literasi dan kualitas pendidikan di Indonesia.

Cross-Cultural Analysis of the Role of Traditional Medicine in Health Access in Indonesia Abdullah, Vera Iriani; Wahidin, Wahidin; Wibowo, Diki Prayugo; Mariani, Ria
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.279

This study investigates the contribution of traditional medicine on health care access in Indonesia through a quantitative cross-cultural approach. Utilizing a sample of 350 individuals that is diverse in terms of age, gender, and ethnic background, the study investigates the prevalence and characteristics that impact the use of traditional medicine. The findings show that traditional healing methods are heavily relied upon, especially by elderly people and members of specific ethnic groups. The necessity for culturally responsive healthcare practices is highlighted by the discovery that cultural beliefs are important determinants of health-seeking behaviour. The results add to the growing body of knowledge about the integration of traditional medicine into modern healthcare systems by highlighting the significance of customizing therapies to the many cultural settings found throughout Indonesia.

Analyzing Knowledge Networks in Health Care through Collaborative Research Exploration Wibowo, Diki Prayugo; Mariani, Ria; Aldo, Novian; Andarmoyo, Sulistyo
West Science Interdisciplinary Studies Vol. 1 No. 10 (2023): West Science Interdisciplinary Studies
Publisher : Westscience Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58812/wsis.v1i10.293

The exploration of collaborative research in healthcare is a dynamic and multifaceted endeavor, as evidenced by analysis of influential articles, citation patterns, and keyword frequencies. Davenport and Prusak's seminal work on knowledge management serves as a foundational foundation, emphasizing the critical role of effective knowledge utilization and sharing in collaborative healthcare research. This research explores linkages with other influential articles, including Scott's examination of social network analysis, Star and Griesemer's insights on institutional ecology, and Tranfield et al.'s methodology on evidence-based knowledge management. Further analysis extends to works on thematic analysis, inter-organizational collaboration, cancer genomics, and qualitative research methods, all of which contribute to a rich tapestry of collaborative healthcare research. Keyword analysis revealed thematic priorities, with a major focus on "Care" and "Experience", emphasizing the human dimension of healthcare. Challenges, technology and organizational aspects emerged as prominent themes, reflecting a holistic approach to collaborative exploration. The interplay between keywords such as "Dynamic", "Mechanisms", and "Performance" underscores the evolving nature of collaborative efforts and the need for strategic mechanisms to address challenges and improve performance. The analysis also highlights contemporary concerns, including the impact of the COVID-19 pandemic, barriers to collaboration, and the intersection of mental health and social media.

Gambaran Tingkat Pengetahuan Masyarakat Dalam Pemanfaatan Daun Sukun Pada Penyakit Degenerative di Kecamatan Cinunuk, Cileunyi Kabupaten Bandung. Riasari, Hesti; Fitriansyah, Sani Nurlaela; Wibowo, Diki Prayugo; Hasanah, Siti Uswatun; Wirasutisna, Komar Ruslan; Restiasari, Anggi
Jurnal Mandala Pengabdian Masyarakat Vol. 5 No. 1 (2024): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v5i1.337

Health is a very important aspect in human life. Degenerative diseases are a serious challenge faced by modern society. Community service aims to describe the level of knowledge of the community in Cinunuk District, Cileunyi, Bandung Regency, as well as analyzing the extent to which breadfruit leaves are used in efforts to prevent and treat degenerative diseases. This community service was carried out on October 26 2023 at the Sebaguna Building, Cinunuk Cileunyi District, Bandung Regency in collaboration with Medina Farma Pharmacy. A total of 78 people took part in counseling activities related to degenerative diseases, plants used as herbal medicines, healthy lifestyles to prevent degenerative diseases, workshops on making breadfruit leaf tea products, health checks such as blood pressure, instant blood sugar, total cholesterol levels, accompanied by health counseling and distribution of pamphlets, 45 of them filled out the questionnaire online using g-form. The results of respondents before the counseling and workshop were 45.89%, indicating that the level of knowledge of respondents was very poor, after the counseling and workshop on making herbal tea preparations there was an increase in the knowledge of the people of Cinunuk District by 81 .48% with a high category of respondents' knowledge regarding degenerative diseases, plants that can be used as herbal medicine, the use of breadfruit leaves and their processing in the form of herbal tea preparations which makes it easier for people to consume them in traditional treatment efforts as preventive and curative.

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