Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Pharmacology and Clinical Pharmacy Research
Rianti Putri
University Of Riau
Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Anti-Bacterial and Anti-Fungal Activities from Macaranga bancana Leaves Extract Rianti Putri; Rudi Hendra; Hilwan Y. Teruna
Pharmacology and Clinical Pharmacy Research Vol 4, No 1
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (221.746 KB) | DOI: 10.15416/pcpr.v4i1.21376

Abstract

Macaranga bancana is one of the Indonesian medicinal plants that is empirically used to treat infectious disease. The aim of this study was to evaluate anti-bacterial and anti-fungal  activities of  M. bancana against human pathogenic microbes, i.e., Escherichia coli, Staphylacoccus aureus, and Candida albicans. The dried leaves of M. bancana were extracted using cold extraction method with n-hexane, dichloromethane, ethylacetate, methanol, and ethanol solvents. The evaluation of anti-microbial activity from these extracts at the concentration of  1000 µg/ml was conducted using microdilution method. Amoxicillin, cephadroxil, and ketoconazole were used as positive controls. All extracts showed 100% inhibitory activity against S. aureus, with the exception of ethanol extract which was 72.8%. Nevertheless, methanol and ethanol extracts showed 100%  inhibitory activity against E. coli, while the lowest activity was shown by n-hexane extract ( 45.2%). All extracts exhibited 100% inhibitory activity against C. albicans.  In conclusion, leaves extract of M. bancana is a potential source of anti-bacterial and anti-fungal agents.  Keywords:  anti-bacterial, anti-fungal, M. bancana, microdilution
Co-Authors Hilwan Y. Teruna Rudi Hendra