Article Per Year (5 Year)
p-Index From 2020 - 2025
0
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kefarmasian Indonesia
Andriliana Trihastuty
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Efek Ekstrak Petroleum Eter Daun Ara (Ficus Racemosa Linn.) pada Indeks Fagositosis Mencit (Mus musculus) Candra Dwipayana Hamdin; Andriliana Trihastuty; Siti Rahmatul Aini
JURNAL ILMU KEFARMASIAN INDONESIA Vol 17 No 2 (2019): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (436 KB) | DOI: 10.35814/jifi.v17i2.686

Abstract

Terpenoid compound from ara’s leaf is known to have immunosuppressant activity by inhibit blood cells proliferation. Immunosuppressant is a group of drugs that can suppress excessive immune responses. The aim of this research was investigated the immunosuppressant effect of petroleum ether from ara’s leaf (Ficus racemosa Linn.) on mice (Mus musculus). The immunosuppressant activity was conducted by carbon clearance method to investigate the ability of phagocytosis with carbon as an antigen that is injected intravenously, followed by determining organ index. All data was analyzed by SPSS. The result showed that at dose of 560 mg/kgbw and 1120 mg/kgbw, extract found to have immunostimulant activity with phagocytic index values respectively ​​of 1.5 and 1.1, while the dose of 1680 mg/kgbw was immunosuppressant with phagocytic index 0.7. The lymphoid organ index showed a significantly difference between petroleum ether from ara leaf extract by dose 1680 mg/kgbw with negative control (p<0.05). Based on the results of the non-specific immune response, it can be concluded that the petroleum ether ara’s leaf extract by dose 1680 mg/kgbw has immunosuppressant activity.
Co-Authors Candra Dwipayana Hamdin Siti Rahmatul Aini